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Ming Li
lim_im@im.ac.cn
Chinese, English
Beijing
University of Chinese Academy of Sciences
Life Sciences
  • 2008-09 to 2014-07 PhD in Science: University of Chinese Academy of Sciences
  • 2004-09 to 2008-07 Bachelor's in Science: Shandong University
  • 2022-10 to Present - Institute of Microbiology, Chinese Academy of Sciences - Researcher
  • 2020-12 to 2022-10 - Institute of Microbiology, Chinese Academy of Sciences - Project Researcher/Young Group Leader
  • 2017-09 to 2020-12 - Institute of Microbiology, Chinese Academy of Sciences - Associate Researcher
  • 2016-11 to 2017-08 - Institute of Microbiology, Chinese Academy of Sciences - Assistant Researcher
  • 2014-11 to 2016-10 - Beijing Institute of Genomics, Chinese Academy of Sciences - Postdoctoral Researcher
  • 2014: Excellent Award of the President of the Chinese Academy of Sciences
  • 2015: Excellent Doctoral Dissertation Award of the Chinese Academy of Sciences
  • 2017: Selected for the Youth Talent Support Program of the China Association for Science and Technology
  • 2020: Member of the Youth Innovation Promotion Association of the Chinese Academy of Sciences
CRISPR-Cas and microbial viral immune mechanisms and their applications
  • Widespread RNA-based cas regulation monitors crRNA abundance and anti-CRISPR proteins, Liu, Chao, Wang, Rui, Li, Jie, Cheng, Feiyue, Shu, Xian, Zhao, Huiwei, Xue, Qiong, Yu, Haiying, Wu, Aici, Wang, Lingyun, Hu, Sushu, Zhang, Yihan, Yang, Jun, Xiang, Hua, Li, Ming, 2023
  • Associate toxin-antitoxin with CRISPR-Cas to kill multidrug-resistant pathogens, Rui Wang, Xian Shu, Huiwei Zhao, Qiong Xue, Chao Liu, Aici Wu, Feiyue Cheng, Lingyun Wang, Yihan Zhang, Jie Feng, Nannan Wu, Ming Li, 2023
  • The toxin-antitoxin RNA guards of CRISPR-Cas evolved high specificity through repeat degeneration, Cheng, Feiyue, Wu, Aici, Liu, Chao, Cao, Xifeng, Wang, Rui, Shu, Xian, Wang, Lingyun, Zhang, Yihan, Xiang, Hua, Li, Ming, 2022
  • Engineered DNase-inactive Cpf1 variants to improve targeting scope for base editing in E. coli, Chen, Zehua, Sun, Jinyuan, Guan, Ying, Li, Ming, Lou, Chunbo, Wu, Bian, 2021
  • Harnessing the type ICRISPR-Cassystems for genome editing in prokaryotes, Xu, Zeling, Li, Yanran, Li, Ming, Xiang, Hua, Yan, Aixin, 2021
  • Toxin-antitoxin RNA pairs safeguard CRISPR-Cas systems, Li, Ming, Gong, Luyao, Cheng, Feiyue, Yu, Haiying, Zhao, Dahe, Wang, Rui, Wang, Tian, Zhang, Shengjie, Zhou, Jian, Shmakov, Sergey A, Koonin, Eugene V, Xiang, Hua, 2021
  • Divergent degeneration of creA antitoxin genes from minimal CRISPRs and the convergent strategy of tRNA-sequestering CreT toxins, Cheng, Feiyue, Wang, Rui, Yu, Haiying, Liu, Chao, Yang, Jun, Xiang, Hua, Li, Ming, 2021
  • Abundant Taxa and Favorable Pathways in the Microbiome of Soda-Saline Lakes in Inner Mongolia, Zhao, Dahe, Zhang, Shengjie, Xue, Qiong, Chen, Junyu, Zhou, Jian, Cheng, Feiyue, Li, Ming, Zhu, Yaxin, Yu, Haiying, Hu, Songnian, Zheng, Yanning, Liu, Shuangjiang, Xiang, Hua, 2020
  • Insights into the metabolism pathway and functional genes of long-chain aliphatic alkane degradation in haloarchaea, Kumar, Sumit, Zhou, Jian, Li, Ming, Xiang, Hua, Zhao, Dahe, 2020
  • Primed adaptation tolerates extensive structural and size variations of the CRISPR RNA guide in Haloarcula hispanica, Gong, Luyao, Li, Ming, Cheng, Feiyue, Zhao, Dahe, Chen, Yihua, Xiang, Hua, 2019
  • Native CRISPR-Cas-Mediated Genome Editing Enables Dissecting and Sensitizing Clinical Multidrug-Resistant P. aeruginosa, Xu, Zeling, Li, Ming, Li, Yanran, Cao, Huiluo, Miao, Lu, Xu, Zhaochao, Higuchi, Yusuke, Yamasaki, Seiji, Nishino, Kunihiko, Woo, Patrick C Y, Xiang, Hua, Yan, Aixin, 2019
  • 探秘生命的第三种形式--我国古菌研究之回顾与展望, 东秀珠, 李猛, 向华, 徐俊, 王风平, 申玉龙, 张臻峰, 韩静, 李洁, 李明, 黄力, 2019
  • 微生物新型防御系统的系统性发现与展望, 李明, 程飞跃, 龚路遥, 向华, 2018
  • Harnessing the native type I-B CRISPR-Cas for genome editing in a polyploid archaeon, Cheng, Feiyue, Gong, Luyao, Zhao, Dahe, Yang, Haibo, Zhou, Jian, Li, Ming, Xiang, Hua, 2017
  • Development of the first gene expression system for Salinicoccus strains with potential application in bioremediation of hypersaline wastewaters, Zhao, Dahe, Yang, Haibo, Chen, Junyu, Cheng, Feiyue, Kumar, Sumit, Han, Jing, Li, Ming, Zhou, Jian, Xiang, Hua, 2017
  • Isolation and complete genome sequence of Halorientalis hydrocarbonoclasticus sp nov., a hydrocarbon-degrading haloarchaeon, Zhao, Dahe, Kumar, Sumit, Zhou, Jian, Wang, Rui, Li, Ming, Xiang, Hua, 2017
  • The spacer size of I-B CRISPR is modulated by the terminal sequence of the protospacer, Li, Ming, Gong, Luyao, Zhao, Dahe, Zhou, Jian, Xiang, Hua, 2017
  • DNA motifs determining the accuracy of repeat duplication during CRISPR adaptation in Haloarcula hispanica, Wang, Rui, Li, Ming, Gong, Luyao, Hu, Songnian, Xiang, Hua, 2016
  • Haloarcula hispanica CRISPR authenticates PAM of a target sequence to prime discriminative adaptation, Li, Ming, Wang, Rui, Xiang, Hua, 2014
  • Adaptation of the Haloarcula hispanica CRISPR-Cas system to a purified virus strictly requires a priming process, Li, Ming, Wang, Rui, Zhao, Dahe, Xiang, Hua, 2014
  • Analysis of the Transcriptional Regulator GlpR, Promoter Elements, and Posttranscriptional Processing Involved in Fructose-Induced Activation of the Phosphoenolpyruvate-Dependent Sugar Phosphotransferase System in Haloferax mediterranei, Cai, Lei, Cai, Shuangfeng, Zhao, Dahe, Wu, Jinhua, Wang, Lei, Liu, Xiaoqing, Li, Ming, Hou, Jing, Zhou, Jian, Liu, Jingfang, Han, Jing, Xiang, Hua, 2014
  • Improving polyhydroxyalkanoate production by knocking out the genes involved in exopolysaccharide biosynthesis in Haloferax mediterranei, Zhao, Dahe, Cai, Lei, Wu, Jinhua, Li, Ming, Liu, Hailong, Han, Jing, Zhou, Jian, Xiang, Hua, 2013
  • Characterization of CRISPR RNA Biogenesis and Cas6 Cleavage-Mediated Inhibition of a Provirus in the Haloarchaeon Haloferax mediterranei, Li, Ming, Liu, Hailong, Han, Jing, Liu, Jingfang, Wang, Rui, Zhao, Dahe, Zhou, Jian, Xiang, Hua, 2013
  • Proteome Reference Map of Haloarcula hispanica and Comparative Proteomic and Transcriptomic Analysis of Polyhydroxyalkanoate Biosynthesis under Genetic and Environmental Perturbations, Liu, Hailong, Luo, Yuanming, Han, Jing, Wu, Jinhua, Wu, Zhenfang, Feng, Deqin, Cai, Shuangfeng, Li, Ming, Liu, Jingfang, Zhou, Jian, Xiang, Hua, 2013
  • Complete Genome Sequence of the Metabolically Versatile Halophilic Archaeon Haloferax mediterranei, a Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) Producer, Han, Jing, Zhang, Fan, Hou, Jing, Liu, Xiaoqing, Li, Ming, Liu, Hailong, Cai, Lei, Zhang, Bing, Chen, Yaping, Zhou, Jian, Hu, Songnian, Xiang, Hua, 2012
  • Complete Genome Sequence of Haloarcula hispanica, a Model Haloarchaeon for Studying Genetics, Metabolism, and Virus-Host Interaction, Liu, Hailong, Wu, Zhenfang, Li, Ming, Zhang, Fan, Zheng, Huajun, Han, Jing, Liu, Jingfang, Zhou, Jian, Wang, Shengyue, Xiang, Hua, 2011
  • Reprogramming the endogenous type I CRISPR‐Cas system for simultaneous gene regulation and editing in Haloarcula hispanica, Kaixin Du, Luyao Gong, Ming Li, Haiying Yu, Hua Xiang, 2021
Crispr-Cas Microbial Viral Immunity Gene Editing Toxin-Antitoxin Prokaryotic Argonaute Phage Defense Molecular Mechanisms Clinical Applications Industrial Applications

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