Professor | Yanhe Li | Asia Growth Partners

Name	Yanhe Li
Contact Information	liyanhe1212@163.com
Language ability	Chinese, English
Province	Shanghai

Name

Yanhe Li

Contact Information

liyanhe1212@163.com

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2021.3-2024.3 Tongji University, Biomedical Engineering, Postdoctoral 2017.9-2021.3 Tongji University, School of Life Sciences and Technology, PhD 2014.9-2017.6 Northwest A&F University, College of Veterinary Medicine, Master's 2010.9-2014.6 Qingdao Agricultural University, College of Animal Science and Technology, Bachelor Published in Nature Cell Biology, Nature Communications, National Science Review Hosted National Natural Science Foundation of China Youth Project, Postdoctoral Surface Project
Work Experience	2024.3 to present - Tongji University, School of Life Sciences and Technology, Associate Professor 2021.3-2024.3 - Tongji University, Biomedical Engineering, Postdoctoral Researcher 2017.9-2021.3 - Tongji University, School of Life Sciences and Technology, PhD Candidate
Awards	China Postdoctoral Innovative Talent Support Plan Shanghai 'Super Postdoctoral' Funding

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2021.3-2024.3 Tongji University, Biomedical Engineering, Postdoctoral
2017.9-2021.3 Tongji University, School of Life Sciences and Technology, PhD
2014.9-2017.6 Northwest A&F University, College of Veterinary Medicine, Master's
2010.9-2014.6 Qingdao Agricultural University, College of Animal Science and Technology, Bachelor
Published in Nature Cell Biology, Nature Communications, National Science Review
Hosted National Natural Science Foundation of China Youth Project, Postdoctoral Surface Project

Work Experience

2024.3 to present - Tongji University, School of Life Sciences and Technology, Associate Professor
2021.3-2024.3 - Tongji University, Biomedical Engineering, Postdoctoral Researcher
2017.9-2021.3 - Tongji University, School of Life Sciences and Technology, PhD Candidate

Awards

China Postdoctoral Innovative Talent Support Plan
Shanghai 'Super Postdoctoral' Funding

Areas of Focus	Epigenetic regulation mechanisms during mammalian peri-implantation embryo development Epigenetic reprogramming molecular mechanisms in cloned embryos Establishment and optimization of gene editing and epigenetic editing techniques
Publications	Inhibition of Wnt activity improves peri-implantation development of somatic cell nuclear transfer embryos, Li Y, Zheng C, Liu Y, He J, Zhang Q, Zhang Y, Kou X, Zhao Y, Liu K, Bai D, Jia Y, Han X, Sheng Y, Yin J, Wang H, Gao S, Liu W, Gao S, 2023 Precise allele-specific genome editing by spatiotemporal control of CRISPR-Cas9 via pronuclear transplantation, Li Y, Weng Y, Bai D, Jia Y, Liu Y, Zhang Y, Kou X, Zhao Y, Ruan J, Chen J, Yin J, Wang H, Teng X, Wang Z, Liu W, Gao S, 2020 Allele-specific H3K9me3 and DNA methylation co-marked CpG-rich regions serve as potential imprinting control regions in pre-implantation embryo, Yang H, Bai D, Li Y, Yu Z, Wang C, Sheng Y, Liu W, Gao S, Zhang Y, 2022 Dynamic replacement of H3.3 affects nuclear reprogramming in early bovine SCNT embryos, Wang Y, Li Y, Luan D, Kang J, He R, Zhang Y, Quan F, 2020 FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development, Wei J, Yu X, Yang L, Liu X, Gao B, Huang B, Dou X, Liu J, Zou Z, Cui XL, Zhang LS, Zhao X, Liu Q, He PC, Sepich-Poore C, Zhong N, Liu W, Li Y, Kou X, Zhao Y, Wu Y, Cheng X, Chen C, An Y, Dong X, Wang H, Shu Q, Hao Z, Duan T, He YY, Li X, Gao S, Gao Y, He C, 2022 N6-methyladenosine regulates maternal RNA maintenance in oocytes and timely RNA decay during mouse maternal-to-zygotic transition, Wu Y, Xu X, Qi M, Chen C, Li M, Yan R, Kou X, Zhao Y, Liu W, Li Y, Liu X, Zhang M, Yi C, Liu H, Xiang J, Wang H, Shen B, Gao Y, Gao S, 2022 Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos, Chen M, Zhu Q, Li C, Kou X, Zhao Y, Li Y, Xu R, Yang L, Yang L, Gu L, Wang H, Liu X, Jiang C, Gao S, 2020 Aberrant H3K4me3 modification of epiblast genes of extraembryonic tissue cause placental defects and implantation failure in mouse IVF embryos, Bai D, Sun J, Chen C, Jia Y, Li Y, Liu K, Zhang Y, Yin J, Liu Y, Han X, Ruan J, Kou X, Zhao Y, Wang H, Wang Z, Chen M, Teng X, Jiang C, Gao S, Liu W, 2022 Melatonin supplementation in the culture medium rescues impaired glucose metabolism in IVF mice offspring, Jia Y, Liu W, Bai D, Zhang Y, Li Y, Liu Y, Yin J, Chen Q, Ye M, Zhao Y, Kou X, Wang H, Gao S, Li K, Chen M, 2022

Areas of Focus

Epigenetic regulation mechanisms during mammalian peri-implantation embryo development
Epigenetic reprogramming molecular mechanisms in cloned embryos
Establishment and optimization of gene editing and epigenetic editing techniques

Publications

Inhibition of Wnt activity improves peri-implantation development of somatic cell nuclear transfer embryos, Li Y, Zheng C, Liu Y, He J, Zhang Q, Zhang Y, Kou X, Zhao Y, Liu K, Bai D, Jia Y, Han X, Sheng Y, Yin J, Wang H, Gao S, Liu W, Gao S, 2023
Precise allele-specific genome editing by spatiotemporal control of CRISPR-Cas9 via pronuclear transplantation, Li Y, Weng Y, Bai D, Jia Y, Liu Y, Zhang Y, Kou X, Zhao Y, Ruan J, Chen J, Yin J, Wang H, Teng X, Wang Z, Liu W, Gao S, 2020
Allele-specific H3K9me3 and DNA methylation co-marked CpG-rich regions serve as potential imprinting control regions in pre-implantation embryo, Yang H, Bai D, Li Y, Yu Z, Wang C, Sheng Y, Liu W, Gao S, Zhang Y, 2022
Dynamic replacement of H3.3 affects nuclear reprogramming in early bovine SCNT embryos, Wang Y, Li Y, Luan D, Kang J, He R, Zhang Y, Quan F, 2020
FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development, Wei J, Yu X, Yang L, Liu X, Gao B, Huang B, Dou X, Liu J, Zou Z, Cui XL, Zhang LS, Zhao X, Liu Q, He PC, Sepich-Poore C, Zhong N, Liu W, Li Y, Kou X, Zhao Y, Wu Y, Cheng X, Chen C, An Y, Dong X, Wang H, Shu Q, Hao Z, Duan T, He YY, Li X, Gao S, Gao Y, He C, 2022
N6-methyladenosine regulates maternal RNA maintenance in oocytes and timely RNA decay during mouse maternal-to-zygotic transition, Wu Y, Xu X, Qi M, Chen C, Li M, Yan R, Kou X, Zhao Y, Liu W, Li Y, Liu X, Zhang M, Yi C, Liu H, Xiang J, Wang H, Shen B, Gao Y, Gao S, 2022
Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos, Chen M, Zhu Q, Li C, Kou X, Zhao Y, Li Y, Xu R, Yang L, Yang L, Gu L, Wang H, Liu X, Jiang C, Gao S, 2020
Aberrant H3K4me3 modification of epiblast genes of extraembryonic tissue cause placental defects and implantation failure in mouse IVF embryos, Bai D, Sun J, Chen C, Jia Y, Li Y, Liu K, Zhang Y, Yin J, Liu Y, Han X, Ruan J, Kou X, Zhao Y, Wang H, Wang Z, Chen M, Teng X, Jiang C, Gao S, Liu W, 2022
Melatonin supplementation in the culture medium rescues impaired glucose metabolism in IVF mice offspring, Jia Y, Liu W, Bai D, Zhang Y, Li Y, Liu Y, Yin J, Chen Q, Ye M, Zhao Y, Kou X, Wang H, Gao S, Li K, Chen M, 2022

Epigenetics Embryo Development Peri-Implantation Mammalian Cloned Embryos Reprogramming Molecular Mechanisms Gene Editing Epigenetic Editing Technique Optimization

Yanhe Li - Tongji University

Jiayu Chen - Tongji University

Chong Li - Tongji University

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