2009-2014: PhD in Biochemistry and Molecular Biology, Beijing Union Medical College, Beijing Institute of Life Sciences
Published research in prestigious journals including Nature and Cell Stem Cell
2023.1-present: Tongji University, School of Life Sciences and Technology, Tenured Professor
2020.12-present: Tongji University, School of Life Sciences and Technology, Professor
2017.12-2020.12: Tongji University, School of Life Sciences and Technology, Associate Professor
2014.10-2017.11: Tongji University, School of Life Sciences and Technology, Assistant Professor
2014.2-2014.10: Tongji University, Advanced Research Institute for Translational Medicine, Assistant Researcher
2020: Second Prize of the National Natural Science Award
2019: First Prize of the Ministry of Education Natural Science Award
2022: Member of the 'National College Huang Danian Style Teacher Team'
2022: 'My Favorite Mentor in the Eyes of Graduate Students' at Tongji University
2022: 'Youth May Fourth Medal' at Tongji University
2020: Outstanding Teacher Award of Tongji University Talent Education Award
Research
Stem Cell and Cell Reprogramming Regulatory Mechanisms in Mammalian Early Embryo Development Mechanisms of Somatic Cell Reprogramming (Cloning and Induced Pluripotent Stem Cells) Regulatory Mechanisms in Human Primordial Germ Cell Development Human Placental Development and Pregnancy-Related Disease Research Disease Model Construction and Research Based on CRISPR/Cas9 Gene Editing Technology
Resetting histone modifications during human prenatal germline development, Gao R, Zeng S, Yang D, Li X, Liu W, Gao Y, Bai D, Zhang L, Chen C, Kang Y, Wang B, Hong W, Wang M, Yin J, Wang H, Deng Q, Gao S, Zhang Y, Chen J, 2023
BMP4 preserves the developmental potential of mESCs through Ube2s- and Chmp4b-mediated chromosomal stability safeguarding, Wang M, Zhao K, Liu M, Wang M, Qiao Z, Yi S, Jiang Y, Kou X, Zhao Y, Yin J, Li T, Wang H, Jiang C, Gao S, Chen J, 2022
Chromatin architecture reorganization during somatic cell reprogramming, Zhao K, Wang M, Gao S, Chen J, 2021
Dux-mediated corrections of aberrant H3K9ac during 2-cell genome activation optimized efficiency of somatic cell nuclear transfer, Guang Y, Zhang L, Liu W, Qiao Z, Shen S, Zhu Q, Gao R, Wang M, Wang M, Li C, Liu M, Sun J, Wang L, Liu W, Cui X, Zhao K, Zang R, Chen M, Liang Z, Wang L, Kou X, Zhao Y, Wang H, Wang Y, Gao S, Chen J, Jiang C, 2021
A high-throughput small molecule screen identifies farrerol as a potentiator of CRISPR/Cas9-mediated genome editing, Zhang W, Chen Y, Yang J, Zhang J, Yu J, Wang M, Zhao X, Wei K, Wan X, Xu X, Jiang Y, Chen J, Gao S, Mao Z, 2020
The SIRT6 activator MDL-800 improves genomic stability and pluripotency of old murine-derived iPS cells, Chen Y, Chen J, Sun X, Yu J, Qian Z, Wu L, Xu X, Wan X, Jiang Y, Zhang J, Gao S, Mao Z, 2020
Mammalian haploid stem cells: establishment, engineering and applications, He W, Chen J, Gao S, 2019
Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1, Li Y, Zhang Z, Chen J, Liu W, Lai W, Liu B, Li X, Liu L, Xu S, Dong Q, Wang M, Duan X, Tan J, Zheng Y, Zhang P, Fan G, Wong J, Xu G, Wang Z, Wang H, Gao S, Zhu B, 2018
Esrrb plays important roles in maintaining self-renewal of trophoblast stem cells (TSCs) and reprogramming somatic cells to induced TSCs, Gao H, Gao R, Zhang L, Xiu W, Zang R, Wang H, Zhang Y, Chen J, Gao Y, Gao S, 2019
Accurate annotation of accessible chromatin in mouse and human primordial germ cells, Li J, Shen S, Chen J, Liu W, Li X, Zhu Q, Wang B, Chen X, Wu L, Wang M, Gu L, Wang H, Yin J, Jiang C, Gao S, 2018
Reduced Self-Diploidization and Improved Survival of Semi-cloned Mice Produced from Androgenetic Haploid Embryonic Stem Cells through Overexpression of Dnmt3b, He W, Zhang X, Zhang Y, Zheng W, Xiong Z, Hu X, Wang M, Zhang L, Zhao K, Qiao Z, Lai W, Lv C, Kou X, Zhao Y, Yin J, Liu W, Jiang Y, Chen M, Xu R, Le R, Li C, Wang H, Wan X, Wang H, Han Z, Jiang C, Gao S, Chen J, 2018
Additive-effect pattern of both ZP2 and ZP3 in human and mouse, Liu W, Bai D, Chen J, Gao S, 2017
Dosage effects of ZP2 and ZP3 heterozygous mutations cause human infertility, Liu W, Li K, Bai D, Yin J, Tang Y, Chi F, Zhang L, Wang Y, Pan J, Liang S, Guo Y, Ruan J, Kou X, Zhao Y, Wang H, Chen J, Teng X, Gao S, 2017
Direct induction of neural progenitor cells transiently passes through a partially reprogrammed state, Gao R, Xiu W, Zhang L, Zang R, Yang L, Wang C, Wang M, Wang M, Yi L, Tang Y, Gao Y, Wang H, Xi J, Liu W, Wang Y, Wen X, Yu Y, Zhang Y, Chen L, Chen J, Gao S, 2017
Maternal Sall4 Is Indispensable for Epigenetic Maturation of Mouse Oocytes, Xu K, Chen X, Yang H, Xu Y, He Y, Wang C, Huang H, Liu B, Liu W, Li J, Kou X, Zhao Y, Zhao K, Zhang L, Hou Z, Wang H, Wang H, Li J, Fan H, Wang F, Gao Y, Zhang Y, Chen J, Gao S, 2017
The combination of Tet1 with Oct4 generates high-quality mouse induced pluripotent stem cells (iPSCs), Chen J, Gao Y, Huang H, Xu K, Chen X, Jiang Y, Li H, Gao S, Tao Y, Wang H, Zhang Y, Wang H, Cai T, Gao S, 2015
The fused in sarcoma protein forms cytoplasmic aggregates in motor neurons derived from integration-free induced pluripotent stem cells generated from a patient with familial amyotrophic lateral sclerosis carrying the FUS-P525L mutation, Liu X, Chen J, Liu W, Li X, Chen Q, Liu T, Gao S, Deng M, 2015
Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming, Gao Y, Chen J, Li K, Wu T, Huang B, Liu W, Kou X, Zhang Y, Huang H, Jiang Y, Yao C, Liu X, Lu Z, Xu Z, Kang L, Chen J, Wang H, Cai T, Gao S, 2013
