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Xin Li
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: English, Chinese
Computational Biology
Human Genetic Variation
Machine Learning
Artificial Intelligence
Multi-Omics
Big Data
Genomics
Bioinformatics
Genetic Research
Data Analysis
Areas of Focus
- Computational Biology - Human Genetic Variation, Machine Learning and Artificial Intelligence Methods Based on Multi-Omics Big Data
Work Experience
- 2020-04 to Present - Chinese Academy of Sciences, Shanghai Institute of Nutrition and Health - Researcher
- 2019-02 to 2020-04 - Chinese Academy of Sciences, Shanghai Institute of Life Sciences - Researcher
- 2016-05 to 2019-02 - Stanford University - Assistant Researcher
- 2012-01 to 2016-05 - Stanford University - Postdoctoral Researcher
- 2010-01 to 2011-12 - Case Western Reserve University - Postdoctoral Researcher
- 2005-08 to 2010-01 - Case Western Reserve University - Ph.D. Student
- 2001-09 to 2005-07 - Tsinghua University - Bachelor's Student
Academic Background & Achievements
- 2005-08 to 2010-01 - Ph.D.: Case Western Reserve University
- 2001-09 to 2005-07 - Bachelor's: Tsinghua University
Publications
- Whole genome sequencing enables new genetic diagnosis for inherited retinal diseases by identifying pathogenic variants, 11th Author, 2024
- Complex clinical manifestations and new insights in RNA sequencing of children with diabetes and WFS1 variants, 7th Author, 2023
- An RNA-informed dosage sensitivity map reflects the intrinsic functional nature of genes, 11th Author, 2023
- Active DHEA uptake in the prostate gland correlates with aggressive prostate cancer, 11th Author, 2023
- Integration of rare expression outlier-associated variants improves polygenic risk prediction, 10th Author, 2022
- The role of Sp140 revealed in IgE and mast cell responses in Collaborative Cross mice, 2nd Author, 2021
- Identification of rare and common regulatory variants in pluripotent cells using population-scale transcriptomics, 7th Author, 2021
- Transcriptomic signatures across human tissues identify functional rare genetic variation, 32nd Author, 2020
- Identification of rare-disease genes using blood transcriptome sequencing and large control cohorts, 5th Author, 2019
- Genetic analyses of human fetal retinal pigment epithelium gene expression suggest ocular disease mechanisms, 8th Author, 2019
- Genetic regulation of gene expression and splicing during a 10-year period of human aging, 5th Author, 2019
- The impact of structural variation on human gene expression, 5th Author, 2017
- The impact of rare variation on gene expression across tissues, 1st Author, 2017
- Population and individual effects of non-coding variants inform genetic risk factors., 4th Author, 2017
- Genetic conflict reflected in tissue-specific maps of genomic imprinting in human and mouse, 5th Author, 2015
- Quantifying RNA allelic ratios by microfluidic multiplex PCR and sequencing, 2nd Author, 2014
- Transcriptome Sequencing of a Large Human Family Identifies the Impact of Rare Noncoding Variants, 11th Author, 2014
- Haplotype Reconstruction in Large Pedigrees with Untyped Individuals through IBD Inference, 1st Author, 2011
- Efficient identification of identical-by-descent status in pedigrees with many untyped individuals, 1st Author, 2010
- AN ALMOST LINEAR TIME ALGORITHM FOR A GENERAL HAPLOTYPE SOLUTION ON TREE PEDIGREES WITH NO RECOMBINATION AND ITS EXTENSIONS, 1st Author, 2009
- EFFICIENT HAPLOTYPE INFERENCE FROM PEDIGREES WITH MISSING DATA USING LINEAR SYSTEMS WITH DISJOINT-SET DATA STRUCTURES, 1st Author, 2008
Awards
- C. W. Cotterman Award (2015): National Level, Special Prize
