Professor | Hui Mei | Asia Growth Partners

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Name	Hui Mei
Contact Information	hui.mei@siat.ac.cn
Language ability	English, Chinese, German
Province	Guangdong

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Name

Hui Mei

Contact Information

hui.mei@siat.ac.cn

Language ability

English, Chinese, German

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2009-04--2015-02 PhD: University of Osnabrück 2006-09--2008-07 Master's: Peking University 2002-09--2006-07 Bachelor's: Peking University
Work Experience	2019-09~Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher 2018-03~2019-07 - Stanford University - Postdoctoral Researcher 2015-10~2018-02 - University of California, Irvine - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2009-04--2015-02 PhD: University of Osnabrück
2006-09--2008-07 Master's: Peking University
2002-09--2006-07 Bachelor's: Peking University

Work Experience

2019-09~Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
2018-03~2019-07 - Stanford University - Postdoctoral Researcher
2015-10~2018-02 - University of California, Irvine - Postdoctoral Researcher

Areas of Focus	Nucleic Acid Chemical Biology Synthetic Biology
Publications	Angew Chem Int Ednull, Hui Mei, 2024 Nucleic Acids Res.null, Hui Mei, 2023 Chemistrynull, Hui Mei, 2022 Acta crystallographica. Section C, Structural chemistrynull, Hui Mei, 2022 Synthesis and polymerase recognition of a pyrrolocytidineTNAtriphosphate, Mei, Hui, Wang, Yajun, Yik, Eric J, Chaput, John C., 2021 以非天然核酸为遗传物质的人工生命构建, 白艳芬, 聂朋, 熊成鹤, 温骏林, 甘海云, 马晴, 胡政, 李雪飞, 于涛, 黄建东, 梅辉, 2021 Synthetic Life with Alternative Nucleic Acids as Genetic Materials, Nie, Peng, Bai, Yanfen, Mei, Hui, 2020 Expanding the chemical diversity of TNA with tUTP derivatives that are substrates for a TNA polymerase, Mei, Hui, Chaput, John C., 2018 Synthesis and Evolution of a Threose Nucleic Acid Aptamer Bearing 7-Deaza-7-Substituted Guanosine Residues, Mei, Hui, Liao, JenYu, Jimenez, Randi M, Wang, Yajun, Bala, Saikat, McCloskey, Cailen, Switzer, Christopher, Chaput, John C., 2018 Synthesis and polymerase activity of a fluorescent cytidine TNA triphosphate analogue, Mei, Hui, Shi, Changhua, Jimenez, Randi M, Wang, Yajun, Kardouh, Miramar, Chaput, John C., 2017 3-Phenyl-5,6,7,8-tetrahydropyrimido4,5-cpyridazin-7-one as nucleobase substitute in DNA: synthesis of the 2 '-deoxyribonucleoside, cyclonucleoside formation, and base pairing in oligonucleotides, Mei, Hui, Ingale, Sachin A, Seela, Frank, 2015 Robust silver-mediated imidazolo-dC base pairs in metal DNA: dinuclear silver bridges with exceptional stability in double helices with parallel and antiparallel strand orientation, Jana, Sunit Kumar, Guo, Xiurong, Mei, Hui, Seela, Frank, 2015 Pyrrolo-dC Metal Base Pairs in the Reverse Watson-Crick Double Helix: Capturing of Silver-Ions, Enhanced Stability of Parallel DNA and Impact of 6-Pyridinyl Residues on Fluorescence and Metal Ion Binding., Mei Hui, 2015 Silver Arrays Inside DNA Duplexes Constructed from Ag+-mediated Pyrrolo-dC – Pyrrolo-dC Base Pairs., Mei Hui, 2014 Imidazolo-dC Metal-Mediated Base Pairs: Purine Nucleosides Capture Two Ag+ Ions and Form a Duplex with the Stability of a Covalent DNA Cross-Link, Mei, Hui, Ingale, Sachin A, Seela, Frank, 2014 Ag+-mediated DNA Base Pairing: Extraordinary Stable Pyrrolo-dC – Pyrrolo-dC Pairs Binding Two Silver Ions., Mei Hui, 2013 Pyrene and bis-pyrene DNA nucleobase conjugates: excimer and monomer fluorescence of linear and dendronized cytosine and 7-deazaguanine click adducts, Mei, Hui, Ingale, Sachin A, Seela, Frank, 2013 Construction and Assembly of Chimeric DNA: Oligonucleotide Hybrid Molecules Composed of Parallel or Antiparallel Duplexes and Tetrameric i-Motifs, Mei, Hui, Budow, Simone, Seela, Frank, 2012 Synthesis of a Fluorescent Cytidine TNA Triphosphate Analogue, Humana Press, 2019

Areas of Focus

Nucleic Acid Chemical Biology
Synthetic Biology

Publications

Angew Chem Int Ednull, Hui Mei, 2024
Nucleic Acids Res.null, Hui Mei, 2023
Chemistrynull, Hui Mei, 2022
Acta crystallographica. Section C, Structural chemistrynull, Hui Mei, 2022
Synthesis and polymerase recognition of a pyrrolocytidineTNAtriphosphate, Mei, Hui, Wang, Yajun, Yik, Eric J, Chaput, John C., 2021
以非天然核酸为遗传物质的人工生命构建, 白艳芬, 聂朋, 熊成鹤, 温骏林, 甘海云, 马晴, 胡政, 李雪飞, 于涛, 黄建东, 梅辉, 2021
Synthetic Life with Alternative Nucleic Acids as Genetic Materials, Nie, Peng, Bai, Yanfen, Mei, Hui, 2020
Expanding the chemical diversity of TNA with tUTP derivatives that are substrates for a TNA polymerase, Mei, Hui, Chaput, John C., 2018
Synthesis and Evolution of a Threose Nucleic Acid Aptamer Bearing 7-Deaza-7-Substituted Guanosine Residues, Mei, Hui, Liao, JenYu, Jimenez, Randi M, Wang, Yajun, Bala, Saikat, McCloskey, Cailen, Switzer, Christopher, Chaput, John C., 2018
Synthesis and polymerase activity of a fluorescent cytidine TNA triphosphate analogue, Mei, Hui, Shi, Changhua, Jimenez, Randi M, Wang, Yajun, Kardouh, Miramar, Chaput, John C., 2017
3-Phenyl-5,6,7,8-tetrahydropyrimido4,5-cpyridazin-7-one as nucleobase substitute in DNA: synthesis of the 2 '-deoxyribonucleoside, cyclonucleoside formation, and base pairing in oligonucleotides, Mei, Hui, Ingale, Sachin A, Seela, Frank, 2015
Robust silver-mediated imidazolo-dC base pairs in metal DNA: dinuclear silver bridges with exceptional stability in double helices with parallel and antiparallel strand orientation, Jana, Sunit Kumar, Guo, Xiurong, Mei, Hui, Seela, Frank, 2015
Pyrrolo-dC Metal Base Pairs in the Reverse Watson-Crick Double Helix: Capturing of Silver-Ions, Enhanced Stability of Parallel DNA and Impact of 6-Pyridinyl Residues on Fluorescence and Metal Ion Binding., Mei Hui, 2015
Silver Arrays Inside DNA Duplexes Constructed from Ag+-mediated Pyrrolo-dC – Pyrrolo-dC Base Pairs., Mei Hui, 2014
Imidazolo-dC Metal-Mediated Base Pairs: Purine Nucleosides Capture Two Ag+ Ions and Form a Duplex with the Stability of a Covalent DNA Cross-Link, Mei, Hui, Ingale, Sachin A, Seela, Frank, 2014
Ag+-mediated DNA Base Pairing: Extraordinary Stable Pyrrolo-dC – Pyrrolo-dC Pairs Binding Two Silver Ions., Mei Hui, 2013
Pyrene and bis-pyrene DNA nucleobase conjugates: excimer and monomer fluorescence of linear and dendronized cytosine and 7-deazaguanine click adducts, Mei, Hui, Ingale, Sachin A, Seela, Frank, 2013
Construction and Assembly of Chimeric DNA: Oligonucleotide Hybrid Molecules Composed of Parallel or Antiparallel Duplexes and Tetrameric i-Motifs, Mei, Hui, Budow, Simone, Seela, Frank, 2012
Synthesis of a Fluorescent Cytidine TNA Triphosphate Analogue, Humana Press, 2019

Nucleic Acids Chemical Biology Synthetic Biology Genetic Materials Polymerase Tna Dna Rna Biopolymers Fluorescent Cytidine

Guo-Qiang Chen - Tsinghua University

Kang Qianjin - Shanghai Jiao Tong University

Qianjin Kang - Shanghai Jiao Tong University

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