Professor | 梅辉 | 数字化转型顾问

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Name	梅辉
Contact Information	hui.mei@siat.ac.cn
Language ability	英语, 中文, 德语
Province	广东

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Name

梅辉

Contact Information

hui.mei@siat.ac.cn

Language ability

英语, 中文, 德语

Province

广东

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2009-04--2015-02 博士: 奥斯纳布吕克大学 2006-09--2008-07 硕士: 北京大学 2002-09--2006-07 学士: 北京大学
Work Experience	2019-09~现在 - 中国科学院深圳先进技术研究院 - 副研究员 2018-03~2019-07 - 斯坦福大学 - 博士后 2015-10~2018-02 - 加州大学尔湾分校 - 博士后

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2009-04--2015-02 博士: 奥斯纳布吕克大学
2006-09--2008-07 硕士: 北京大学
2002-09--2006-07 学士: 北京大学

Work Experience

2019-09~现在 - 中国科学院深圳先进技术研究院 - 副研究员
2018-03~2019-07 - 斯坦福大学 - 博士后
2015-10~2018-02 - 加州大学尔湾分校 - 博士后

Areas of Focus	核酸化学生物学合成生物学
Publications	Angew Chem Int Ednull, 梅辉, 2024 Nucleic Acids Res.null, 梅辉, 2023 Chemistrynull, 梅辉, 2022 Acta crystallographica. Section C, Structural chemistrynull, 梅辉, 2022 Synthesis and polymerase recognition of a pyrrolocytidineTNAtriphosphate, 梅辉, 王亚军, 易克, 埃里克, 查普特, 约翰, 2021 以非天然核酸为遗传物质的人工生命构建, 白艳芬, 聂朋, 熊成鹤, 温骏林, 甘海云, 马晴, 胡政, 李雪飞, 于涛, 黄建东, 梅辉, 2021 Synthetic Life with Alternative Nucleic Acids as Genetic Materials, 聂朋, 白艳芬, 梅辉, 2020 Expanding the chemical diversity of TNA with tUTP derivatives that are substrates for a TNA polymerase, 梅辉, 查普特, 约翰, 2018 Synthesis and Evolution of a Threose Nucleic Acid Aptamer Bearing 7-Deaza-7-Substituted Guanosine Residues, 梅辉, 廖珍玉, 吉梅内斯, 兰迪, 王亚军, 巴拉, 赛卡特, 麦克洛斯基, 凯伦, 斯威策, 克里斯托弗, 查普特, 约翰, 2018 Synthesis and polymerase activity of a fluorescent cytidine TNA triphosphate analogue, 梅辉, 施昌华, 吉梅内斯, 兰迪, 王亚军, 卡尔杜, 米拉马尔, 查普特, 约翰, 2017 3-Phenyl-5,6,7,8-tetrahydropyrimido4,5-cpyridazin-7-one as nucleobase substitute in DNA: synthesis of the 2 '-deoxyribonucleoside, cyclonucleoside formation, and base pairing in oligonucleotides, 梅辉, 英加尔, 萨钦, 塞拉, 弗兰克, 2015 Robust silver-mediated imidazolo-dC base pairs in metal DNA: dinuclear silver bridges with exceptional stability in double helices with parallel and antiparallel strand orientation, 贾纳, 苏尼特, 郭秀荣, 梅辉, 塞拉, 弗兰克, 2015 Pyrrolo-dC Metal Base Pairs in the Reverse Watson-Crick Double Helix: Capturing of Silver-Ions, Enhanced Stability of Parallel DNA and Impact of 6-Pyridinyl Residues on Fluorescence and Metal Ion Binding., 梅辉, 2015 Silver Arrays Inside DNA Duplexes Constructed from Ag+-mediated Pyrrolo-dC – Pyrrolo-dC Base Pairs., 梅辉, 2014 Imidazolo-dC Metal-Mediated Base Pairs: Purine Nucleosides Capture Two Ag+ Ions and Form a Duplex with the Stability of a Covalent DNA Cross-Link, 梅辉, 英加尔, 萨钦, 塞拉, 弗兰克, 2014 Ag+-mediated DNA Base Pairing: Extraordinary Stable Pyrrolo-dC – Pyrrolo-dC Pairs Binding Two Silver Ions., 梅辉, 2013 Pyrene and bis-pyrene DNA nucleobase conjugates: excimer and monomer fluorescence of linear and dendronized cytosine and 7-deazaguanine click adducts, 梅辉, 英加尔, 萨钦, 塞拉, 弗兰克, 2013 Construction and Assembly of Chimeric DNA: Oligonucleotide Hybrid Molecules Composed of Parallel or Antiparallel Duplexes and Tetrameric i-Motifs, 梅辉, 布多, 西蒙, 塞拉, 弗兰克, 2012 Synthesis of a Fluorescent Cytidine TNA Triphosphate Analogue, Humana Press, 2019

Areas of Focus

核酸化学生物学
合成生物学

Publications

Angew Chem Int Ednull, 梅辉, 2024
Nucleic Acids Res.null, 梅辉, 2023
Chemistrynull, 梅辉, 2022
Acta crystallographica. Section C, Structural chemistrynull, 梅辉, 2022
Synthesis and polymerase recognition of a pyrrolocytidineTNAtriphosphate, 梅辉, 王亚军, 易克, 埃里克, 查普特, 约翰, 2021
以非天然核酸为遗传物质的人工生命构建, 白艳芬, 聂朋, 熊成鹤, 温骏林, 甘海云, 马晴, 胡政, 李雪飞, 于涛, 黄建东, 梅辉, 2021
Synthetic Life with Alternative Nucleic Acids as Genetic Materials, 聂朋, 白艳芬, 梅辉, 2020
Expanding the chemical diversity of TNA with tUTP derivatives that are substrates for a TNA polymerase, 梅辉, 查普特, 约翰, 2018
Synthesis and Evolution of a Threose Nucleic Acid Aptamer Bearing 7-Deaza-7-Substituted Guanosine Residues, 梅辉, 廖珍玉, 吉梅内斯, 兰迪, 王亚军, 巴拉, 赛卡特, 麦克洛斯基, 凯伦, 斯威策, 克里斯托弗, 查普特, 约翰, 2018
Synthesis and polymerase activity of a fluorescent cytidine TNA triphosphate analogue, 梅辉, 施昌华, 吉梅内斯, 兰迪, 王亚军, 卡尔杜, 米拉马尔, 查普特, 约翰, 2017
3-Phenyl-5,6,7,8-tetrahydropyrimido4,5-cpyridazin-7-one as nucleobase substitute in DNA: synthesis of the 2 '-deoxyribonucleoside, cyclonucleoside formation, and base pairing in oligonucleotides, 梅辉, 英加尔, 萨钦, 塞拉, 弗兰克, 2015
Robust silver-mediated imidazolo-dC base pairs in metal DNA: dinuclear silver bridges with exceptional stability in double helices with parallel and antiparallel strand orientation, 贾纳, 苏尼特, 郭秀荣, 梅辉, 塞拉, 弗兰克, 2015
Pyrrolo-dC Metal Base Pairs in the Reverse Watson-Crick Double Helix: Capturing of Silver-Ions, Enhanced Stability of Parallel DNA and Impact of 6-Pyridinyl Residues on Fluorescence and Metal Ion Binding., 梅辉, 2015
Silver Arrays Inside DNA Duplexes Constructed from Ag+-mediated Pyrrolo-dC – Pyrrolo-dC Base Pairs., 梅辉, 2014
Imidazolo-dC Metal-Mediated Base Pairs: Purine Nucleosides Capture Two Ag+ Ions and Form a Duplex with the Stability of a Covalent DNA Cross-Link, 梅辉, 英加尔, 萨钦, 塞拉, 弗兰克, 2014
Ag+-mediated DNA Base Pairing: Extraordinary Stable Pyrrolo-dC – Pyrrolo-dC Pairs Binding Two Silver Ions., 梅辉, 2013
Pyrene and bis-pyrene DNA nucleobase conjugates: excimer and monomer fluorescence of linear and dendronized cytosine and 7-deazaguanine click adducts, 梅辉, 英加尔, 萨钦, 塞拉, 弗兰克, 2013
Construction and Assembly of Chimeric DNA: Oligonucleotide Hybrid Molecules Composed of Parallel or Antiparallel Duplexes and Tetrameric i-Motifs, 梅辉, 布多, 西蒙, 塞拉, 弗兰克, 2012
Synthesis of a Fluorescent Cytidine TNA Triphosphate Analogue, Humana Press, 2019

核酸化学生物学合成生物学遗传物质聚合酶 Tna Dna Rna 生物聚合物荧光胞苷

冯畅 - 上海大学

Area of Focus
生物标志物 | 癌症 | 检测 | 诊断 | Dna | Rna | 放大 | 分子生物学 | 生物化学 | 临床研究

赵烨 - 浙江大学

郑梅珍 - 南方科技大学

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