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梅辉
Life Science
中国科学院大学
广东
Language: 英语, 中文, 德语
核酸
化学生物学
合成生物学
遗传物质
聚合酶
Tna
Dna
Rna
生物聚合物
荧光胞苷
Areas of Focus
- 核酸化学生物学
- 合成生物学
Work Experience
- 2019-09~现在 - 中国科学院深圳先进技术研究院 - 副研究员
- 2018-03~2019-07 - 斯坦福大学 - 博士后
- 2015-10~2018-02 - 加州大学尔湾分校 - 博士后
Academic Background & Achievements
- 2009-04--2015-02 博士: 奥斯纳布吕克大学
- 2006-09--2008-07 硕士: 北京大学
- 2002-09--2006-07 学士: 北京大学
Publications
- Angew Chem Int Ednull, 梅辉, 2024
- Nucleic Acids Res.null, 梅辉, 2023
- Chemistrynull, 梅辉, 2022
- Acta crystallographica. Section C, Structural chemistrynull, 梅辉, 2022
- Synthesis and polymerase recognition of a pyrrolocytidineTNAtriphosphate, 梅辉, 王亚军, 易克, 埃里克, 查普特, 约翰, 2021
- 以非天然核酸为遗传物质的人工生命构建, 白艳芬, 聂朋, 熊成鹤, 温骏林, 甘海云, 马晴, 胡政, 李雪飞, 于涛, 黄建东, 梅辉, 2021
- Synthetic Life with Alternative Nucleic Acids as Genetic Materials, 聂朋, 白艳芬, 梅辉, 2020
- Expanding the chemical diversity of TNA with tUTP derivatives that are substrates for a TNA polymerase, 梅辉, 查普特, 约翰, 2018
- Synthesis and Evolution of a Threose Nucleic Acid Aptamer Bearing 7-Deaza-7-Substituted Guanosine Residues, 梅辉, 廖珍玉, 吉梅内斯, 兰迪, 王亚军, 巴拉, 赛卡特, 麦克洛斯基, 凯伦, 斯威策, 克里斯托弗, 查普特, 约翰, 2018
- Synthesis and polymerase activity of a fluorescent cytidine TNA triphosphate analogue, 梅辉, 施昌华, 吉梅内斯, 兰迪, 王亚军, 卡尔杜, 米拉马尔, 查普特, 约翰, 2017
- 3-Phenyl-5,6,7,8-tetrahydropyrimido4,5-cpyridazin-7-one as nucleobase substitute in DNA: synthesis of the 2 '-deoxyribonucleoside, cyclonucleoside formation, and base pairing in oligonucleotides, 梅辉, 英加尔, 萨钦, 塞拉, 弗兰克, 2015
- Robust silver-mediated imidazolo-dC base pairs in metal DNA: dinuclear silver bridges with exceptional stability in double helices with parallel and antiparallel strand orientation, 贾纳, 苏尼特, 郭秀荣, 梅辉, 塞拉, 弗兰克, 2015
- Pyrrolo-dC Metal Base Pairs in the Reverse Watson-Crick Double Helix: Capturing of Silver-Ions, Enhanced Stability of Parallel DNA and Impact of 6-Pyridinyl Residues on Fluorescence and Metal Ion Binding., 梅辉, 2015
- Silver Arrays Inside DNA Duplexes Constructed from Ag+-mediated Pyrrolo-dC – Pyrrolo-dC Base Pairs., 梅辉, 2014
- Imidazolo-dC Metal-Mediated Base Pairs: Purine Nucleosides Capture Two Ag+ Ions and Form a Duplex with the Stability of a Covalent DNA Cross-Link, 梅辉, 英加尔, 萨钦, 塞拉, 弗兰克, 2014
- Ag+-mediated DNA Base Pairing: Extraordinary Stable Pyrrolo-dC – Pyrrolo-dC Pairs Binding Two Silver Ions., 梅辉, 2013
- Pyrene and bis-pyrene DNA nucleobase conjugates: excimer and monomer fluorescence of linear and dendronized cytosine and 7-deazaguanine click adducts, 梅辉, 英加尔, 萨钦, 塞拉, 弗兰克, 2013
- Construction and Assembly of Chimeric DNA: Oligonucleotide Hybrid Molecules Composed of Parallel or Antiparallel Duplexes and Tetrameric i-Motifs, 梅辉, 布多, 西蒙, 塞拉, 弗兰克, 2012
- Synthesis of a Fluorescent Cytidine TNA Triphosphate Analogue, Humana Press, 2019
