Upload Avatar (500 x 500)
Honglei Ma
Life Science
University of Chinese Academy of Sciences
Shandong
Language: Chinese, English
Natural Products
Synthesis Pathways
Mechanism Analysis
Microbial Physiology
Metabolic Mechanisms
Biochemistry
Molecular Biology
Genetic Engineering
Biotechnology
Bioenergy
Areas of Focus
- Natural product synthesis pathway mechanism analysis
- Microbial important physiological and metabolic molecular mechanisms
Work Experience
- 2022-05 to Present - Chinese Academy of Sciences, Qingdao Institute of Bioenergy and Bioprocess Technology - Researcher
- 2021-04 to 2022-03 - Shandong University - Researcher
- 2018-09 to 2021-03 - Shanghai Institute of Materia Medica - Associate Researcher
- 2016-07 to 2018-08 - Shanghai Institute of Materia Medica - Postdoctoral Researcher
- 2014-09 to 2016-03 - The Scripps Research Institute - Joint Training
- 2010-07 to 2011-08 - ACON Biotech (Hangzhou) Co., Ltd. - Blood Glucose R&D Engineer
- 2009-08 to 2010-06 - Zhejiang Hisun Pharmaceutical Co., Ltd. - Drug Formulation R&D Technician
Academic Background & Achievements
- 2014-09 to 2016-03 Joint Training: The Scripps Research Institute
- 2011-09 to 2016-07 Ph.D.: Shanghai Institute of Materia Medica
- 2005-09 to 2009-07 Bachelor's Degree: Jilin University
Publications
- CvkR is a MerR-type transcriptional repressor of class 2 type V-K CRISPR-associated transposase systems, Nature Communications, 2023
- Identification and mechanism of G protein-biased ligands for chemokine receptor CCR1, Nature Chemical Biology, 2022
- Molecular insights into ligand recognition and activation of chemokine receptors CCR2 and CCR3, Cell Discovery, 2022
- Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor, Nature Communications, 2021
- Structural insights into the activation of GLP-1R by a small molecule agonist, Cell Research, 2020
- C10ORF12 modulates PRC2 histone methyltransferase activity and H3K27me3 levels, Acta Pharmacologica Sinica, 2019
- A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex, Science Advances, 2017
- Structural basis for recognition of diverse transcriptional repressors by the TOPLESS family of corepressors, Science Advances, 2015
- DWARF 53 acts as a repressor of strigolactone signalling in rice, Nature, 2013
Awards
- Sanofi - Chinese Academy of Sciences Shanghai Institute of Life Sciences Outstanding Young Talent Award (2020)
- Chinese Academy of Sciences President's Excellence Award (2016)
