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Pengcheng Ma
kunmapch@163.com
Chinese, English
Yunnan

Academic Information

University of Chinese Academy of Sciences
Life Sciences
  • 2008-09--2013-06 PhD in Science: Kunming Institute of Zoology, Chinese Academy of Sciences
  • 2004-09--2008-06 Bachelor's in Science: School of Life Sciences, Ludong University
  • 2019-01~Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
  • 2013-07~2018-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher
  • 2008-09~2013-06 - Kunming Institute of Zoology, Chinese Academy of Sciences - PhD Student
  • 2004-09~2008-06 - School of Life Sciences, Ludong University - Bachelor's Student

Research

Mechanisms of Neural Development and Neurodevelopmental Diseases
  • Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma, 11th Author, 2023
  • Joint profiling of gene expression and chromatin accessibility during amphioxus development at single-cell resolution, 1st Author, 2022
  • RNF220 is an E3 ubiquitin ligase for AMPA receptors to regulate synaptic transmission, 1st Author, 2022
  • Sequential stabilization of RNF220 by RLIM and ZC4H2 during cerebellum development and Shh-group medulloblastoma progression, 0th Author, 2022
  • RNF220 mediates K63-linked polyubiquitination of STAT1 and promotes host defense, 2nd Author, 2021
  • Haploinsufficiency of the TDP43 ubiquitin E3 ligase RNF220 leads to ALS-like motor neuron defects in the mouse, 1st Author, 2021
  • RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling, 1st Author, 2020
  • ZC4H2 stabilizes RNF220 to pattern ventral spinal cord through modulating Shh/Gli signaling, 1st Author, 2020
  • Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development, 2nd Author, 2020
  • Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning, 1st Author, 2019
  • RNF220-mediated K63-linked polyubiquitination stabilizes Olig proteins during oligodendroglial development and myelination, 9th Author
Keywords
Neural Development Neurodevelopmental Diseases Mechanisms Regulation Neurobiology Developmental Biology Cell Biology Genetics Molecular Biology Neuroscience
Related Professors
Jing Xie - Tongji University
Area of Focus
Asymmetric Division | Stem Cells | Epigenetics | Cell Fate | Histone Modifications | Gene Expression | Tissue Regeneration | Disease Mechanisms | Molecular Biology | Cell Biology
Jianfeng Chang - Tongji University
Area of Focus
Dna Methylation | Histone Modification | Gene Expression | Cellular Senescence | Oncology | Chromatin Structure | Gene Regulation | Molecular Biology | Biotechnology | Cell Biology
You Wu - Tongji University
Area of Focus
Embryonic Development | Epigenetics | Rna Modifications | Transcriptomics | Sequencing Technology | Gene Regulation | Molecular Biology | Cell Biology | Genetics | Biotechnology
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