Upload Avatar (500 x 500)
Pengcheng Ma
Life Science
University of Chinese Academy of Sciences
Yunnan
Language: Chinese, English
Neural Development
Neurodevelopmental Diseases
Mechanisms
Regulation
Neurobiology
Developmental Biology
Cell Biology
Genetics
Molecular Biology
Neuroscience
Areas of Focus
- Mechanisms of Neural Development and Neurodevelopmental Diseases
Work Experience
- 2019-01~Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
- 2013-07~2018-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher
- 2008-09~2013-06 - Kunming Institute of Zoology, Chinese Academy of Sciences - PhD Student
- 2004-09~2008-06 - School of Life Sciences, Ludong University - Bachelor's Student
Academic Background & Achievements
- 2008-09--2013-06 PhD in Science: Kunming Institute of Zoology, Chinese Academy of Sciences
- 2004-09--2008-06 Bachelor's in Science: School of Life Sciences, Ludong University
Publications
- Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma, 11th Author, 2023
- Joint profiling of gene expression and chromatin accessibility during amphioxus development at single-cell resolution, 1st Author, 2022
- RNF220 is an E3 ubiquitin ligase for AMPA receptors to regulate synaptic transmission, 1st Author, 2022
- Sequential stabilization of RNF220 by RLIM and ZC4H2 during cerebellum development and Shh-group medulloblastoma progression, 0th Author, 2022
- RNF220 mediates K63-linked polyubiquitination of STAT1 and promotes host defense, 2nd Author, 2021
- Haploinsufficiency of the TDP43 ubiquitin E3 ligase RNF220 leads to ALS-like motor neuron defects in the mouse, 1st Author, 2021
- RNF220 is required for cerebellum development and regulates medulloblastoma progression through epigenetic modulation of Shh signaling, 1st Author, 2020
- ZC4H2 stabilizes RNF220 to pattern ventral spinal cord through modulating Shh/Gli signaling, 1st Author, 2020
- Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development, 2nd Author, 2020
- Fine-Tuning of Shh/Gli Signaling Gradient by Non-proteolytic Ubiquitination during Neural Patterning, 1st Author, 2019
- RNF220-mediated K63-linked polyubiquitination stabilizes Olig proteins during oligodendroglial development and myelination, 9th Author
