Areas of Focus
- Biosynthesis and Molecular Regulation of Secondary Metabolites
Work Experience
- 2018-10~Present - Institute of Microbiology, Chinese Academy of Sciences - Associate Researcher
- 2009-08~2018-10 - Institute of Microbiology, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
- 2005-09--2009-06 Ph.D. in Science: Institute of Microbiology, Chinese Academy of Sciences
- 2002-09--2005-06 M.Sc. in Science: Huazhong Agricultural University
- 1998-09--2002-06 B.Sc. in Science: Henan Agricultural University
Publications
- A Berberine Bridge Enzyme-like Oxidase Mediates the Cage-like Acresorbicillinol C Biosynthesis, Corresponding Author, 2024
- Exploring the Role of Active Functional Microbiota in Flavor Generation by Integrated Metatranscriptomics and Metabolomics during Niulanshan Baijiu Fermentation, First Author, 2023
- Sorbicillinoid Derivatives with the Radical Scavenging Activities from the Marine-Derived Fungus Acremonium chrysogenum C10, Corresponding Author, 2022
- Metatranscriptomics Unravel Composition, Drivers, and Functions of the Active Microorganisms in Light-Flavor Liquor Fermentation, First Author, 2022
- Characterization of a Prenyltransferase for Iso-A82775C Biosynthesis and Generation of New Congeners of Chloropestolides, First Author, 2018
- Enhancing the production of cephalosporin C through modulating the autophagic process of Acremonium chrysogenum, Fourth Author, 2018
- A Myb transcription factor represses conidiation and cephalosporin C production in Acremonium chrysogenum, Eighth Author, 2018
- Research advances on molecular regulation of filamentous fungal secondary metabolism in China, First Author, 2018
- Metabolic engineering of Acremonium chrysogenum for improving cephalosporin C production independent of methionine stimulation, Third Author, 2018
- A GATA-type transcription factor AcAREB for nitrogen metabolism is involved in regulation of cephalosporin biosynthesis in Acremonium chrysogenum, Second Author, 2017
- Research progresses and trends of secondary metabolites in filamentous fungi, First Author, 2015
- The autophagy-related gene Acatg1 is involved in conidiation and cephalosporin production in Acremonium chrysogenum, Second Author, 2014
- Disruption of the nitrogen regulatory gene AcareA in Acremonium chrysogenum leads to reduction of cephalosporin production and repression of nitrogen metabolism, Second Author, 2013
- Disruption of rimP-SC , encoding a ribosome assembly cofactor, markedly enhances the production of several antibiotics in Streptomyces coelicolor, First Author, 2013
- SabR enhances nikkomycin production via regulating the transcriptional level of sanG , a pathway-specific regulatory gene in Streptomyces ansochromogenes, First Author, 2011
- The pleiotropic regulator AdpA-L directly controls the pathway-specific activator of nikkomycin biosynthesis in Streptomyces ansochromogenes, First Author, 2009
