Professor | Yinhua Lu | Asia Growth Partners

Name	Yinhua Lu
Contact Information	yhlu@shnu.edu.cn
Language ability	Chinese, English
Province	Shanghai

Name

Yinhua Lu

Contact Information

yhlu@shnu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Normal University
Faculty	Life Sciences
Academic Background & Achievements	2000-2003 PhD: Nanjing Agricultural University 1997-2000 Master's: Yangzhou University 1992-1997 Bachelor's: Yangzhou University
Work Experience	2017/7-present, Shanghai Normal University - Researcher 2013/12-2017/6, Shanghai Institute of Plant Physiology and Ecology, CAS - Researcher 2009/3-2010/2, University of Erlangen, Germany - Visiting Scholar 2008/3-2013/11, Shanghai Institute of Plant Physiology and Ecology, CAS - Associate Researcher 2006/06-2008/02, Shanghai Institute of Plant Physiology and Ecology, CAS - Assistant Researcher 2003/07-2006/05, Shanghai Institute of Plant Physiology and Ecology, CAS - Postdoctoral Researcher
Awards	Sanofi-Shanghai Institute of Life Sciences Excellent Young Talent Fund, 2012

University/Lab Affiliation and Title

Shanghai Normal University

Faculty

Life Sciences

Academic Background & Achievements

2000-2003 PhD: Nanjing Agricultural University
1997-2000 Master's: Yangzhou University
1992-1997 Bachelor's: Yangzhou University

Work Experience

2017/7-present, Shanghai Normal University - Researcher
2013/12-2017/6, Shanghai Institute of Plant Physiology and Ecology, CAS - Researcher
2009/3-2010/2, University of Erlangen, Germany - Visiting Scholar
2008/3-2013/11, Shanghai Institute of Plant Physiology and Ecology, CAS - Associate Researcher
2006/06-2008/02, Shanghai Institute of Plant Physiology and Ecology, CAS - Assistant Researcher
2003/07-2006/05, Shanghai Institute of Plant Physiology and Ecology, CAS - Postdoctoral Researcher

Awards

Sanofi-Shanghai Institute of Life Sciences Excellent Young Talent Fund, 2012

Areas of Focus	Molecular regulation of microbial natural drug biosynthesis Development of microbial natural drugs based on synthetic biology strategies
Publications	A novel two-component, GluR-K, involved in glutamate sensing and uptake in Streptomyces coelicolor, Li L, Jiang WH, Lu YH, 2017 New strategies and approaches for engineering biosynthetic gene clusters of microbial natural products, Li L, Jiang WH, Lu YH, 2017 Multiplexed site-specific genome engineering for overproducing bioactive secondary metabolites in actinomycetes, Li L, Zheng GS, Chen J, Ge M, Jiang WH, Lu YH, 2017 Direct involvement of the master nitrogen metabolism regulator in antibiotic biosynthesis in Streptomyces, He JM, Zhu H, Zheng GS, Liu PP, Wang J, Zhao GP, Zhu GQ, Jiang WH, Lu YH, 2016 A stepwise increase in pristinamycin II biosynthesis by Streptomyces pristinaespiralis through combinatorial metabolic engineering, Li L, Zhao YW, Ruan LJ, Yang S, Ge M, Jiang WH, Lu YH, 2015 Involvement of the TetR-type regulator PaaR in the regulation of pristinamycin I biosynthesis through effect on precursor supply in Streptomyces pristinaespiralis, Zhao YW, Feng RR, Zheng GS, Tian JZ, Ruan LJ, Ge M, Jiang WH, Lu YH, 2015 PapR6, a putative atypical response regulator, functions as a pathway-specific activator of pristinamycin II biosynthesis in Streptomyces pristinaespiralis, Dun JL, Zhao YW, Zheng GS, Zhu H, Ruan LJ, Wang WF, Ge M, Jiang WH, Lu YH, 2015 Identification of two novel regulatory genes involved in pristinamycin biosynthesis and elucidation of the mechanism for AtrA-p-mediated regulation in Streptomyces pristinaespiralis, Wang WF, Tian JZ, Li L, Ge M, Zhu H, Zheng GS, Huang H, Ruan LJ, Jiang WH, Lu YH, 2015 Identification of two-component system AfsQ1/Q2 regulon and its cross-regulation with GlnR in Streptomyces coelicolor, Wang R, Mast Y, Wang J, Zhang WW, Zhao GP, Wohlleben W, Lu YH, Jiang WH, 2013 Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor, Yu ZY, Zhu H, Dang FJ, Zhang WW, Qin ZJ, Yang S, Tan HH, Lu YH, Jiang WH, 2012

Areas of Focus

Molecular regulation of microbial natural drug biosynthesis
Development of microbial natural drugs based on synthetic biology strategies

Publications

A novel two-component, GluR-K, involved in glutamate sensing and uptake in Streptomyces coelicolor, Li L, Jiang WH, Lu YH, 2017
New strategies and approaches for engineering biosynthetic gene clusters of microbial natural products, Li L, Jiang WH, Lu YH, 2017
Multiplexed site-specific genome engineering for overproducing bioactive secondary metabolites in actinomycetes, Li L, Zheng GS, Chen J, Ge M, Jiang WH, Lu YH, 2017
Direct involvement of the master nitrogen metabolism regulator in antibiotic biosynthesis in Streptomyces, He JM, Zhu H, Zheng GS, Liu PP, Wang J, Zhao GP, Zhu GQ, Jiang WH, Lu YH, 2016
A stepwise increase in pristinamycin II biosynthesis by Streptomyces pristinaespiralis through combinatorial metabolic engineering, Li L, Zhao YW, Ruan LJ, Yang S, Ge M, Jiang WH, Lu YH, 2015
Involvement of the TetR-type regulator PaaR in the regulation of pristinamycin I biosynthesis through effect on precursor supply in Streptomyces pristinaespiralis, Zhao YW, Feng RR, Zheng GS, Tian JZ, Ruan LJ, Ge M, Jiang WH, Lu YH, 2015
PapR6, a putative atypical response regulator, functions as a pathway-specific activator of pristinamycin II biosynthesis in Streptomyces pristinaespiralis, Dun JL, Zhao YW, Zheng GS, Zhu H, Ruan LJ, Wang WF, Ge M, Jiang WH, Lu YH, 2015
Identification of two novel regulatory genes involved in pristinamycin biosynthesis and elucidation of the mechanism for AtrA-p-mediated regulation in Streptomyces pristinaespiralis, Wang WF, Tian JZ, Li L, Ge M, Zhu H, Zheng GS, Huang H, Ruan LJ, Jiang WH, Lu YH, 2015
Identification of two-component system AfsQ1/Q2 regulon and its cross-regulation with GlnR in Streptomyces coelicolor, Wang R, Mast Y, Wang J, Zhang WW, Zhao GP, Wohlleben W, Lu YH, Jiang WH, 2013
Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor, Yu ZY, Zhu H, Dang FJ, Zhang WW, Qin ZJ, Yang S, Tan HH, Lu YH, Jiang WH, 2012

Biosynthesis Microbial Natural Drugs Molecular Regulation Synthetic Biology Gene Clusters Metabolic Engineering Secondary Metabolites Streptomyces Antibiotics

Hua Yuan - Shanghai Normal University

Linquan Bai - Shanghai Jiao Tong University

Hongbo Hu - Shanghai Jiao Tong University

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