Professor | 芦银华 | 数字化转型顾问

Name	芦银华
Contact Information	yhlu@shnu.edu.cn
Language ability	中文, 英语
Province	上海

Name

芦银华

Contact Information

yhlu@shnu.edu.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	上海师范大学
Faculty	Life Sciences
Academic Background & Achievements	2000-2003 博士：南京农业大学 1997-2000 硕士：扬州大学 1992-1997 学士：扬州大学
Work Experience	2017/7-至今，上海师范大学 - 研究员 2013/12-2017/6，中科院上海生科院植物生理生态研究所 - 研究员 2009/3-2010/2，德国埃尔朗根大学 - 访问学者 2008/3-2013/11，中科院上海生科院植物生理生态研究所 - 副研究员 2006/06-2008/02，中科院上海生科院植物生理生态研究所 - 助理研究员 2003/07-2006/05，中科院上海生科院植物生理生态研究所 - 博士后
Awards	赛诺菲—上海生命科学研究院优秀青年人才奖励基金，2012年

University/Lab Affiliation and Title

上海师范大学

Faculty

Life Sciences

Academic Background & Achievements

2000-2003 博士：南京农业大学
1997-2000 硕士：扬州大学
1992-1997 学士：扬州大学

Work Experience

2017/7-至今，上海师范大学 - 研究员
2013/12-2017/6，中科院上海生科院植物生理生态研究所 - 研究员
2009/3-2010/2，德国埃尔朗根大学 - 访问学者
2008/3-2013/11，中科院上海生科院植物生理生态研究所 - 副研究员
2006/06-2008/02，中科院上海生科院植物生理生态研究所 - 助理研究员
2003/07-2006/05，中科院上海生科院植物生理生态研究所 - 博士后

Awards

赛诺菲—上海生命科学研究院优秀青年人才奖励基金，2012年

Areas of Focus	微生物天然药物生物合成的分子调控基于合成生物学策略的微生物天然药物研发
Publications	A novel two-component, GluR-K, involved in glutamate sensing and uptake in Streptomyces coelicolor, Li L, Jiang WH, Lu YH, 2017 New strategies and approaches for engineering biosynthetic gene clusters of microbial natural products, Li L, Jiang WH, Lu YH, 2017 Multiplexed site-specific genome engineering for overproducing bioactive secondary metabolites in actinomycetes, Li L, Zheng GS, Chen J, Ge M, Jiang WH, Lu YH, 2017 Direct involvement of the master nitrogen metabolism regulator in antibiotic biosynthesis in Streptomyces, He JM, Zhu H, Zheng GS, Liu PP, Wang J, Zhao GP, Zhu GQ, Jiang WH, Lu YH, 2016 A stepwise increase in pristinamycin II biosynthesis by Streptomyces pristinaespiralis through combinatorial metabolic engineering, Li L, Zhao YW, Ruan LJ, Yang S, Ge M, Jiang WH, Lu YH, 2015 Involvement of the TetR-type regulator PaaR in the regulation of pristinamycin I biosynthesis through effect on precursor supply in Streptomyces pristinaespiralis, Zhao YW, Feng RR, Zheng GS, Tian JZ, Ruan LJ, Ge M, Jiang WH, Lu YH, 2015 PapR6, a putative atypical response regulator, functions as a pathway-specific activator of pristinamycin II biosynthesis in Streptomyces pristinaespiralis, Dun JL, Zhao YW, Zheng GS, Zhu H, Ruan LJ, Wang WF, Ge M, Jiang WH, Lu YH, 2015 Identification of two novel regulatory genes involved in pristinamycin biosynthesis and elucidation of the mechanism for AtrA-p-mediated regulation in Streptomyces pristinaespiralis, Wang WF, Tian JZ, Li L, Ge M, Zhu H, Zheng GS, Huang H, Ruan LJ, Jiang WH, Lu YH, 2015 Identification of two-component system AfsQ1/Q2 regulon and its cross-regulation with GlnR in Streptomyces coelicolor, Wang R, Mast Y, Wang J, Zhang WW, Zhao GP, Wohlleben W, Lu YH, Jiang WH, 2013 Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor, Yu ZY, Zhu H, Dang FJ, Zhang WW, Qin ZJ, Yang S, Tan HH, Lu YH, Jiang WH, 2012

Areas of Focus

微生物天然药物生物合成的分子调控
基于合成生物学策略的微生物天然药物研发

Publications

A novel two-component, GluR-K, involved in glutamate sensing and uptake in Streptomyces coelicolor, Li L, Jiang WH, Lu YH, 2017
New strategies and approaches for engineering biosynthetic gene clusters of microbial natural products, Li L, Jiang WH, Lu YH, 2017
Multiplexed site-specific genome engineering for overproducing bioactive secondary metabolites in actinomycetes, Li L, Zheng GS, Chen J, Ge M, Jiang WH, Lu YH, 2017
Direct involvement of the master nitrogen metabolism regulator in antibiotic biosynthesis in Streptomyces, He JM, Zhu H, Zheng GS, Liu PP, Wang J, Zhao GP, Zhu GQ, Jiang WH, Lu YH, 2016
A stepwise increase in pristinamycin II biosynthesis by Streptomyces pristinaespiralis through combinatorial metabolic engineering, Li L, Zhao YW, Ruan LJ, Yang S, Ge M, Jiang WH, Lu YH, 2015
Involvement of the TetR-type regulator PaaR in the regulation of pristinamycin I biosynthesis through effect on precursor supply in Streptomyces pristinaespiralis, Zhao YW, Feng RR, Zheng GS, Tian JZ, Ruan LJ, Ge M, Jiang WH, Lu YH, 2015
PapR6, a putative atypical response regulator, functions as a pathway-specific activator of pristinamycin II biosynthesis in Streptomyces pristinaespiralis, Dun JL, Zhao YW, Zheng GS, Zhu H, Ruan LJ, Wang WF, Ge M, Jiang WH, Lu YH, 2015
Identification of two novel regulatory genes involved in pristinamycin biosynthesis and elucidation of the mechanism for AtrA-p-mediated regulation in Streptomyces pristinaespiralis, Wang WF, Tian JZ, Li L, Ge M, Zhu H, Zheng GS, Huang H, Ruan LJ, Jiang WH, Lu YH, 2015
Identification of two-component system AfsQ1/Q2 regulon and its cross-regulation with GlnR in Streptomyces coelicolor, Wang R, Mast Y, Wang J, Zhang WW, Zhao GP, Wohlleben W, Lu YH, Jiang WH, 2013
Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor, Yu ZY, Zhu H, Dang FJ, Zhang WW, Qin ZJ, Yang S, Tan HH, Lu YH, Jiang WH, 2012

生物合成微生物天然药物分子调控合成生物学基因簇代谢工程次级代谢产物链霉菌抗生素

白林泉 - 上海交通大学

邓子新 - 上海交通大学

黄显清 - 上海交通大学

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