Areas of Focus
- 微生物天然药物生物合成的分子调控
- 基于合成生物学策略的微生物天然药物研发
Work Experience
- 2017/7-至今，上海师范大学 - 研究员
- 2013/12-2017/6，中科院上海生科院植物生理生态研究所 - 研究员
- 2009/3-2010/2，德国埃尔朗根大学 - 访问学者
- 2008/3-2013/11，中科院上海生科院植物生理生态研究所 - 副研究员
- 2006/06-2008/02，中科院上海生科院植物生理生态研究所 - 助理研究员
- 2003/07-2006/05，中科院上海生科院植物生理生态研究所 - 博士后
Academic Background & Achievements
- 2000-2003 博士：南京农业大学
- 1997-2000 硕士：扬州大学
- 1992-1997 学士：扬州大学
Publications
- A novel two-component, GluR-K, involved in glutamate sensing and uptake in Streptomyces coelicolor, Li L, Jiang WH, Lu YH, 2017
- New strategies and approaches for engineering biosynthetic gene clusters of microbial natural products, Li L, Jiang WH, Lu YH, 2017
- Multiplexed site-specific genome engineering for overproducing bioactive secondary metabolites in actinomycetes, Li L, Zheng GS, Chen J, Ge M, Jiang WH, Lu YH, 2017
- Direct involvement of the master nitrogen metabolism regulator in antibiotic biosynthesis in Streptomyces, He JM, Zhu H, Zheng GS, Liu PP, Wang J, Zhao GP, Zhu GQ, Jiang WH, Lu YH, 2016
- A stepwise increase in pristinamycin II biosynthesis by Streptomyces pristinaespiralis through combinatorial metabolic engineering, Li L, Zhao YW, Ruan LJ, Yang S, Ge M, Jiang WH, Lu YH, 2015
- Involvement of the TetR-type regulator PaaR in the regulation of pristinamycin I biosynthesis through effect on precursor supply in Streptomyces pristinaespiralis, Zhao YW, Feng RR, Zheng GS, Tian JZ, Ruan LJ, Ge M, Jiang WH, Lu YH, 2015
- PapR6, a putative atypical response regulator, functions as a pathway-specific activator of pristinamycin II biosynthesis in Streptomyces pristinaespiralis, Dun JL, Zhao YW, Zheng GS, Zhu H, Ruan LJ, Wang WF, Ge M, Jiang WH, Lu YH, 2015
- Identification of two novel regulatory genes involved in pristinamycin biosynthesis and elucidation of the mechanism for AtrA-p-mediated regulation in Streptomyces pristinaespiralis, Wang WF, Tian JZ, Li L, Ge M, Zhu H, Zheng GS, Huang H, Ruan LJ, Jiang WH, Lu YH, 2015
- Identification of two-component system AfsQ1/Q2 regulon and its cross-regulation with GlnR in Streptomyces coelicolor, Wang R, Mast Y, Wang J, Zhang WW, Zhao GP, Wohlleben W, Lu YH, Jiang WH, 2013
- Differential regulation of antibiotic biosynthesis by DraR-K, a novel two-component system in Streptomyces coelicolor, Yu ZY, Zhu H, Dang FJ, Zhang WW, Qin ZJ, Yang S, Tan HH, Lu YH, Jiang WH, 2012
Awards
- 赛诺菲—上海生命科学研究院优秀青年人才奖励基金，2012年
