Professor | Linquan Bai | Asia Growth Partners

Name	Linquan Bai
Contact Information	bailq@sjtu.edu.cn
Language ability	English, Chinese, German
Province	Shanghai

Name

Linquan Bai

Contact Information

bailq@sjtu.edu.cn

Language ability

English, Chinese, German

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	1992 Bachelor of Science in Microbiology, Shandong University 1995 Master of Science in Microbiology, Huazhong Agricultural University 1998 PhD in Molecular Biology, Huazhong Agricultural University
Work Experience	1999-2002 Postdoctoral Researcher, Department of Chemistry, University of Washington 2002-present Professor, School of Life Sciences and Technology, Shanghai Jiao Tong University 2006-2007 Research Collaboration on Biosynthetic Regulation, Microbiology Institute, University of Tuebingen
Awards	2006 Top Ten Scientific and Technological Progresses in Chinese Universities 2007 Second Prize of Natural Science from the Ministry of Education 2008 Second Prize of National Natural Science 2007 New Century Excellent Talents Support Plan by the Ministry of Education 2008 Shuguang Talent Plan by Shanghai Municipal Education Commission 2009 Meiji Dairy Life Science Award 2009 11th China Youth Science and Technology Award

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

1992 Bachelor of Science in Microbiology, Shandong University
1995 Master of Science in Microbiology, Huazhong Agricultural University
1998 PhD in Molecular Biology, Huazhong Agricultural University

Work Experience

1999-2002 Postdoctoral Researcher, Department of Chemistry, University of Washington
2002-present Professor, School of Life Sciences and Technology, Shanghai Jiao Tong University
2006-2007 Research Collaboration on Biosynthetic Regulation, Microbiology Institute, University of Tuebingen

Awards

2006 Top Ten Scientific and Technological Progresses in Chinese Universities
2007 Second Prize of Natural Science from the Ministry of Education
2008 Second Prize of National Natural Science
2007 New Century Excellent Talents Support Plan by the Ministry of Education
2008 Shuguang Talent Plan by Shanghai Municipal Education Commission
2009 Meiji Dairy Life Science Award
2009 11th China Youth Science and Technology Award

Areas of Focus	Biosynthesis of Jinggangmycin/Validamycin Biosynthesis mechanisms and combinatorial biosynthesis of Ansamycin antibiotics Secondary metabolite biosynthesis gene resource mining
Publications	Structural and functional analysis of validoxylamine A 7'-phosphate synthase ValL involved in validamycin A biosynthesis, Zheng L, Zhou X, Zhang H, Ji X, Li L, Huang L, Bai L, Zhang H, 2012 Unveiling the biosynthetic puzzle of destruxins in Metarhizium species, Wang B, Kang Q, Lu Y, Bai L, Wang C, 2012 Dual carbamoylations on the polyketide and glycosyl moiety by asm21 result in extended ansamitocin biosynthesis, Li Y, Zhao P, Kang Q, Ma J, Bai L, Deng Z, 2011 Biosynthesis of 3,5-AHBA-derived natural products, Kang Q, Shen Y, Bai L, 2012 Cloning and characterization of the polyether salinomycin biosynthesis gene cluster of Streptomyces albus XM211, Jiang C, Wang H, Kang Q, Liu J, Bai L, 2012 Over-expression of UDP-glucose pyrophosphorylase increases validamycin A but decreases validoxylamine A production in Streptomyces hygroscopicus var. jinggangensis 5008, Zhou X, Wu H, Li Z, Zhou X, Bai L, Deng Z, 2011 Toward steadfast growth of antibiotic research in China: From natural products to engineered biosynthesis, Kang Q, Bai L, Deng Z, 2011 Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis, Qiu J, Zhuo Y, Zhu D, Zhou X, Zhang L, Bai L, Deng Z, 2011 N-methylation of the amide bond by methyltransferase asm10 in ansamitocin biosynthesis, Wu Y, Kang Q, Shen Y, Su W, Bai L, Floss HG, 2011 Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS, Wu Y, Kang Q, Shen Y, Su W, Bai L, 2011

Areas of Focus

Biosynthesis of Jinggangmycin/Validamycin
Biosynthesis mechanisms and combinatorial biosynthesis of Ansamycin antibiotics
Secondary metabolite biosynthesis gene resource mining

Publications

Structural and functional analysis of validoxylamine A 7'-phosphate synthase ValL involved in validamycin A biosynthesis, Zheng L, Zhou X, Zhang H, Ji X, Li L, Huang L, Bai L*, Zhang H*, 2012
Unveiling the biosynthetic puzzle of destruxins in Metarhizium species, Wang B, Kang Q, Lu Y, Bai L, Wang C, 2012
Dual carbamoylations on the polyketide and glycosyl moiety by asm21 result in extended ansamitocin biosynthesis, Li Y, Zhao P, Kang Q, Ma J, Bai L*, Deng Z, 2011
Biosynthesis of 3,5-AHBA-derived natural products, Kang Q, Shen Y, Bai L*, 2012
Cloning and characterization of the polyether salinomycin biosynthesis gene cluster of Streptomyces albus XM211, Jiang C, Wang H, Kang Q, Liu J, Bai L*, 2012
Over-expression of UDP-glucose pyrophosphorylase increases validamycin A but decreases validoxylamine A production in Streptomyces hygroscopicus var. jinggangensis 5008, Zhou X, Wu H, Li Z, Zhou X, Bai L*, Deng Z, 2011
Toward steadfast growth of antibiotic research in China: From natural products to engineered biosynthesis, Kang Q, Bai L*, Deng Z, 2011
Overexpression of the ABC transporter AvtAB increases avermectin production in Streptomyces avermitilis, Qiu J, Zhuo Y, Zhu D, Zhou X, Zhang L, Bai L*, Deng Z, 2011
N-methylation of the amide bond by methyltransferase asm10 in ansamitocin biosynthesis, Wu Y, Kang Q, Shen Y, Su W, Bai L*, Floss HG, 2011
Cloning and functional analysis of the naphthomycin biosynthetic gene cluster in Streptomyces sp. CS, Wu Y, Kang Q, Shen Y, Su W, Bai L*, 2011

Antibiotics Agricultural Antibiotics Gene Clusters Genetic Systems Structural Genes Temperature Regulation Metabolic Engineering Genomics Post-Modification Biosynthetic Regulation

Huaqi Pan - University of Chinese Academy of Sciences

Yinhua Lu - Shanghai Normal University

Meifeng Tao - Shanghai Jiao Tong University

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