Professor | Meifeng Tao | Asia Growth Partners

Name	Meifeng Tao
Contact Information	tao_meifeng@sjtu.edu.cn
Language ability	English, Chinese
Province	Shanghai

Name

Meifeng Tao

Contact Information

tao_meifeng@sjtu.edu.cn

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	1992 Bachelor in Biochemistry, Wuhan University 1999 PhD in Life Science Technology, Huazhong Agricultural University
Work Experience	1992-1994 - Guilin Second Pharmaceutical Factory - Technician 1999-2008 - Huazhong Agricultural University, Life Science Technology College - Lecturer, Associate Professor, Doctoral Supervisor, PI at the National Key Laboratory of Agricultural Microbiology 1999-2001 (6 months each year) - John Innes Centre, UK - Visiting Scholar 2005-2007 - University of Wisconsin-Madison, School of Pharmacy - Research Assistant 2009-2017 - Shanghai Jiao Tong University - Special Research Fellow 2017-present - Shanghai Jiao Tong University - Professor

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

1992 Bachelor in Biochemistry, Wuhan University
1999 PhD in Life Science Technology, Huazhong Agricultural University

Work Experience

1992-1994 - Guilin Second Pharmaceutical Factory - Technician
1999-2008 - Huazhong Agricultural University, Life Science Technology College - Lecturer, Associate Professor, Doctoral Supervisor, PI at the National Key Laboratory of Agricultural Microbiology
1999-2001 (6 months each year) - John Innes Centre, UK - Visiting Scholar
2005-2007 - University of Wisconsin-Madison, School of Pharmacy - Research Assistant
2009-2017 - Shanghai Jiao Tong University - Special Research Fellow
2017-present - Shanghai Jiao Tong University - Professor

Areas of Focus	Microbial natural product drug discovery, biosynthesis, and metabolic regulation Microbial functional genomics and chassis cell optimization Antibiotic high-yield breeding technology and its production application
Publications	Genome-wide mutagenesis links multiple metabolic pathways with actinorhodin production in Streptomyces coelicolor, Xu Z, Li Y, Wang Y, Deng Z, Tao M, 2019 Engineered Streptomyces lividans strains for optimal identification and expression of cryptic biosynthetic gene clusters, Peng Q, Gao G, Lü J, Long Q, Chen X, Zhang F, Xu M, Liu K, Wang Y, Deng Z, Li Z, Tao M, 2018 Biosynthesis of tropolones in Streptomyces spp: interweaving biosynthesis and degradation of phenylacetic acid and hydroxylations on tropone ring, Chen X, Xu M, Lü J, Lin S, Deng Z, Tao M, 2018 Formation of an angular aromatic polyketide from a linear anthrene precursor via oxidative rearrangement, Gao G, Liu X, Xu M, Jiang M, Lin S, Tao M, 2017 Large-scale transposition mutagenesis of Streptomyces coelicolor identifies hundreds of genes influencing antibiotic biosynthesis, Xu Z, Wang Y, Chater K F, Ou HY, Xu HH, Deng Z, Tao M, 2017 Iteratively improving natamycin production in Streptomyces gilvosporeus by a large operon-reporter based strategy, Wang Y, Tao Z, Zheng H, Zhang F, Long Q, Deng Z, Tao M, 2016 Functional genome mining for metabolites encoded by large gene clusters through heterologous expression of a whole-genome bacterial artificial chromosome library in Streptomyces spp, Xu M, Wang Y, Zhao Z, Pang X, Deng Z, Tao M, 2016 Hybrubins: bipyrrole tetramic acids obtained by crosstalk between a truncated undecylprodigiosin pathway and heterologous tetramic acid biosynthetic genes, Zhao Z, Shi T, Xu M, Pang X, Tao M, 2016 A cellulose synthase-like protein involved in hyphal tip growth and morphological differentiation in Streptomyces, Xu H, Chater K F, Deng Z, Tao M, 2008 A genetic and bioinformatic analysis of Streptomyces coelicolor genes containing TTA codons, possible targets for regulation by a developmentally significant tRNA, Li W, Wu J, Tao W, Zhao C, Wang Y, He X, Chandra G, Zhou X, Deng Z, Chater K F, Tao M, 2007

Areas of Focus

Microbial natural product drug discovery, biosynthesis, and metabolic regulation
Microbial functional genomics and chassis cell optimization
Antibiotic high-yield breeding technology and its production application

Publications

Genome-wide mutagenesis links multiple metabolic pathways with actinorhodin production in Streptomyces coelicolor, Xu Z, Li Y, Wang Y, Deng Z, Tao M, 2019
Engineered Streptomyces lividans strains for optimal identification and expression of cryptic biosynthetic gene clusters, Peng Q, Gao G, Lü J, Long Q, Chen X, Zhang F, Xu M, Liu K, Wang Y, Deng Z, Li Z, Tao M, 2018
Biosynthesis of tropolones in Streptomyces spp: interweaving biosynthesis and degradation of phenylacetic acid and hydroxylations on tropone ring, Chen X, Xu M, Lü J, Lin S, Deng Z, Tao M, 2018
Formation of an angular aromatic polyketide from a linear anthrene precursor via oxidative rearrangement, Gao G, Liu X, Xu M, Jiang M, Lin S, Tao M, 2017
Large-scale transposition mutagenesis of Streptomyces coelicolor identifies hundreds of genes influencing antibiotic biosynthesis, Xu Z, Wang Y, Chater K F, Ou HY, Xu HH, Deng Z, Tao M, 2017
Iteratively improving natamycin production in Streptomyces gilvosporeus by a large operon-reporter based strategy, Wang Y, Tao Z, Zheng H, Zhang F, Long Q, Deng Z, Tao M, 2016
Functional genome mining for metabolites encoded by large gene clusters through heterologous expression of a whole-genome bacterial artificial chromosome library in Streptomyces spp, Xu M, Wang Y, Zhao Z, Pang X, Deng Z, Tao M, 2016
Hybrubins: bipyrrole tetramic acids obtained by crosstalk between a truncated undecylprodigiosin pathway and heterologous tetramic acid biosynthetic genes, Zhao Z, Shi T, Xu M, Pang X, Tao M, 2016
A cellulose synthase-like protein involved in hyphal tip growth and morphological differentiation in Streptomyces, Xu H, Chater K F, Deng Z, Tao M, 2008
A genetic and bioinformatic analysis of Streptomyces coelicolor genes containing TTA codons, possible targets for regulation by a developmentally significant tRNA, Li W, Wu J, Tao W, Zhao C, Wang Y, He X, Chandra G, Zhou X, Deng Z, Chater K F, Tao M, 2007

Drug Discovery Biosynthesis Metabolic Regulation Microbial Natural Products Genomics Cell Optimization Antibiotics High-Yield Breeding Production Application

Yinhua Lu - Shanghai Normal University

Hua Yuan - Shanghai Normal University

Linquan Bai - Shanghai Jiao Tong University

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