Professor | 陶美凤 | 数字化转型顾问

Name	陶美凤
Contact Information	tao_meifeng@sjtu.edu.cn
Language ability	英语, 汉语
Province	上海

Name

陶美凤

Contact Information

tao_meifeng@sjtu.edu.cn

Language ability

英语, 汉语

Province

上海

University/Lab Affiliation and Title	上海交通大学
Faculty	Life Sciences
Academic Background & Achievements	1992年生物化学学士，武汉大学 1999年生命科技学院博士，华中农业大学
Work Experience	1992-1994年 - 桂林市第二制药厂 - 技术员 1999-2008年 - 华中农业大学生命科技学院 - 讲师、副教授、博导、农业微生物学国家重点实验室PI 1999-2001年(每年6个月) - 英国约翰.英纳斯中心 - 访问学者 2005-2007年 - 美国威斯康星大学药学院 - 研究助理 2009-2017年 - 上海交通大学 - 特别研究员 2017年至今 - 上海交通大学 - 教授

University/Lab Affiliation and Title

上海交通大学

Faculty

Life Sciences

Academic Background & Achievements

1992年生物化学学士，武汉大学
1999年生命科技学院博士，华中农业大学

Work Experience

1992-1994年 - 桂林市第二制药厂 - 技术员
1999-2008年 - 华中农业大学生命科技学院 - 讲师、副教授、博导、农业微生物学国家重点实验室PI
1999-2001年(每年6个月) - 英国约翰.英纳斯中心 - 访问学者
2005-2007年 - 美国威斯康星大学药学院 - 研究助理
2009-2017年 - 上海交通大学 - 特别研究员
2017年至今 - 上海交通大学 - 教授

Areas of Focus	微生物天然产物药物的挖掘、生物合成及代谢调控微生物功能基因组及底盘细胞优化抗生素高产育种新技术及其生产应用
Publications	Genome-wide mutagenesis links multiple metabolic pathways with actinorhodin production in Streptomyces coelicolor, Xu Z, Li Y, Wang Y, Deng Z, Tao M, 2019 Engineered Streptomyces lividans strains for optimal identification and expression of cryptic biosynthetic gene clusters, Peng Q, Gao G, Lü J, Long Q, Chen X, Zhang F, Xu M, Liu K, Wang Y, Deng Z, Li Z, Tao M, 2018 Biosynthesis of tropolones in Streptomyces spp: interweaving biosynthesis and degradation of phenylacetic acid and hydroxylations on tropone ring, Chen X, Xu M, Lü J, Lin S, Deng Z, Tao M, 2018 Formation of an angular aromatic polyketide from a linear anthrene precursor via oxidative rearrangement, Gao G, Liu X, Xu M, Jiang M, Lin S, Tao M, 2017 Large-scale transposition mutagenesis of Streptomyces coelicolor identifies hundreds of genes influencing antibiotic biosynthesis, Xu Z, Wang Y, Chater K F, Ou HY, Xu HH, Deng Z, Tao M, 2017 Iteratively improving natamycin production in Streptomyces gilvosporeus by a large operon-reporter based strategy, Wang Y, Tao Z, Zheng H, Zhang F, Long Q, Deng Z, Tao M, 2016 Functional genome mining for metabolites encoded by large gene clusters through heterologous expression of a whole-genome bacterial artificial chromosome library in Streptomyces spp, Xu M, Wang Y, Zhao Z, Pang X, Deng Z, Tao M, 2016 Hybrubins: bipyrrole tetramic acids obtained by crosstalk between a truncated undecylprodigiosin pathway and heterologous tetramic acid biosynthetic genes, Zhao Z, Shi T, Xu M, Pang X, Tao M, 2016 A cellulose synthase-like protein involved in hyphal tip growth and morphological differentiation in Streptomyces, Xu H, Chater K F, Deng Z, Tao M, 2008 A genetic and bioinformatic analysis of Streptomyces coelicolor genes containing TTA codons, possible targets for regulation by a developmentally significant tRNA, Li W, Wu J, Tao W, Zhao C, Wang Y, He X, Chandra G, Zhou X, Deng Z, Chater K F, Tao M, 2007

Areas of Focus

微生物天然产物药物的挖掘、生物合成及代谢调控
微生物功能基因组及底盘细胞优化
抗生素高产育种新技术及其生产应用

Publications

Genome-wide mutagenesis links multiple metabolic pathways with actinorhodin production in Streptomyces coelicolor, Xu Z, Li Y, Wang Y, Deng Z, Tao M, 2019
Engineered Streptomyces lividans strains for optimal identification and expression of cryptic biosynthetic gene clusters, Peng Q, Gao G, Lü J, Long Q, Chen X, Zhang F, Xu M, Liu K, Wang Y, Deng Z, Li Z, Tao M, 2018
Biosynthesis of tropolones in Streptomyces spp: interweaving biosynthesis and degradation of phenylacetic acid and hydroxylations on tropone ring, Chen X, Xu M, Lü J, Lin S, Deng Z, Tao M, 2018
Formation of an angular aromatic polyketide from a linear anthrene precursor via oxidative rearrangement, Gao G, Liu X, Xu M, Jiang M, Lin S, Tao M, 2017
Large-scale transposition mutagenesis of Streptomyces coelicolor identifies hundreds of genes influencing antibiotic biosynthesis, Xu Z, Wang Y, Chater K F, Ou HY, Xu HH, Deng Z, Tao M, 2017
Iteratively improving natamycin production in Streptomyces gilvosporeus by a large operon-reporter based strategy, Wang Y, Tao Z, Zheng H, Zhang F, Long Q, Deng Z, Tao M, 2016
Functional genome mining for metabolites encoded by large gene clusters through heterologous expression of a whole-genome bacterial artificial chromosome library in Streptomyces spp, Xu M, Wang Y, Zhao Z, Pang X, Deng Z, Tao M, 2016
Hybrubins: bipyrrole tetramic acids obtained by crosstalk between a truncated undecylprodigiosin pathway and heterologous tetramic acid biosynthetic genes, Zhao Z, Shi T, Xu M, Pang X, Tao M, 2016
A cellulose synthase-like protein involved in hyphal tip growth and morphological differentiation in Streptomyces, Xu H, Chater K F, Deng Z, Tao M, 2008
A genetic and bioinformatic analysis of Streptomyces coelicolor genes containing TTA codons, possible targets for regulation by a developmentally significant tRNA, Li W, Wu J, Tao W, Zhao C, Wang Y, He X, Chandra G, Zhou X, Deng Z, Chater K F, Tao M, 2007

药物发现生物合成代谢调控微生物天然产物基因组学细胞优化抗生素高产育种生产应用

陶美凤 - 上海交通大学

杨敏 - 华中科技大学

陶庆华 - 清华大学

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