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Ge Qu
Life Science
University of Chinese Academy of Sciences
Tianjin
Language: Chinese, English
Enzyme Rational Design
Enzyme Engineering
Biocatalysis
Synthetic Biology
Catalysis
Protein Engineering
Metabolic Engineering
Biotechnology
Molecular Biology
Chemical Synthesis
Areas of Focus
- Enzyme Rational Design
- Enzyme Engineering
- Biocatalysis
- Synthetic Biology
Publications
- Engineered enzymes for the synthesis of pharmaceuticals and other high-value products, 11th Author, 2024
- Book review of 'Enzyme engineering: Selective catalysts for applications in biotechnology, organic chemistry, and life science', 3rd Author, 2023
- Catalytic Promiscuity-driven Redesign of Enzyme Functions, 1st Author, 2023
- Characterization and engineering of cephalosporin C acylases to produce 7-Aminocephalosporanic acid, 5th Author, 2023
- Substitutability of metal-binding sites in an alcohol dehydrogenase, 4th Author, 2022
- Biosynthesis of a rosavin natural product in Escherichia coli by glycosyltransferase rational design and artificial pathway construction, 2nd Author, 2022
- Whole-cell Biotransformation of Penicillin G by a Three-enzyme Co-expression System with Engineered Deacetoxycephalosporin C Synthase, 11th Author, 2022
- Unlocking the stereoselectivity and substrate acceptance of enzymes: Proline induced loop engineering test, 1st Author, 2022
- Rational design of geranylgeranyl diphosphate synthase enhances carotenoid production and improves photosynthetic efficiency in Nicotiana tabacum, 2nd Author, 2022
- Rational design and applications of industrial proteins, 1st Author, 2022
- Biosynthesis of β-lactam nuclei in yeast, 11th Author, 2022
- Carboxylic acid reductases enable intramolecular lactamization reactions, 5th Author, 2022
- Whole-cell biocatalytic synthesis of S-(4-chlorophenyl)-(pyridin-2-yl) methanol in a liquid-liquid biphasic microreaction system, 4th Author, 2021
- Unlocking the Stereoselectivity and Substrate Acceptance of Enzymes: Proline-Induced Loop Engineering Test, 1st Author, 2021
- Near-perfect control of the regioselective glucosylation enabled by rational design of glycosyltransferases, 2nd Author, 2021
- High-Throughput Fluorescence Assay for Ketone Detection and Its Applications in Enzyme Mining and Protein Engineering, 3rd Author, 2020
- Identification of Absidia orchidis steroid 11 beta-hydroxylation system and its application in engineering Saccharomyces cerevisiae for one-step biotransformation to produce hydrocortisone, 3rd Author, 2020
- Identification of Absidia orchidis steroid 11 beta-hydroxylation system and its application in engineering Saccharomyces cerevisiae for one-step biotransformation to produce hydrocortisone, 3rd Author, 2020
- The Crucial Role of Methodology Development in Directed Evolution of Selective Enzymes, 1st Author, 2020
- Data mining of amine dehydrogenases for the synthesis of enantiopure amino alcohols, 2nd Author, 2020
- Machine learning-assisted enzyme directed evolution, 2nd Author, 2020
- Identification of a novel cytochrome P450 enzyme that catalyzes the C-2 alpha hydroxylation of pentacyclic triterpenoids and its application in yeast cell factories, 5th Author, 2019
- Statistical Analysis of the Benefits of Focused Saturation Mutagenesis in Directed Evolution Based on Reduced Amino Acid Alphabets, 2nd Author, 2019
- Structure-function relationships of industrial enzymes, 2nd Author, 2019
- Protein engineering: from directed evolution to computational design, 1st Author, 2019
- Laboratory evolution of an alcohol dehydrogenase towards enantioselective reduction of difficult-to-reduce ketones, 1st Author, 2019
- The Nobel Prize in Chemistry 2018: the directed evolution of enzymes and the phage display technologies, 1st Author, 2019
- Utility of B-Factors in Protein Science: Interpreting Rigidity, Flexibility, and Internal Motion and Engineering Thermostability, 3rd Author, 2019
- Conformational Dynamics-Guided Loop Engineering of an Alcohol Dehydrogenase: Capture, Turnover and Enantioselective Transformation of Difficult-to-Reduce Ketones, 2nd Author, 2019
- Identification of a novel cytochrome P450 enzyme that catalyzes the C-2 alpha hydroxylation of pentacyclic triterpenoids and its application in yeast cell factories, 5th Author, 2019
- Computational Insights into the Catalytic Mechanism of Bacterial Carboxylic Acid Reductase, 1st Author, 2019
- Computer-assisted engineering of the catalytic activity of a carboxylic acid reductase, 1st Author, 2019
- Biocatalysis of carboxylic acid reductases: phylogenesis, catalytic mechanism and potential applications, 1st Author, 2018
- Recent advances in directed evolution, 1st Author, 2018
- Biosynthesis of dendroketose from different carbon sources using in vitro and in vivo metabolic engineering strategies, 3rd Author, 2018
- Methodology Development in Directed Evolution: Exploring Options when Applying Triple-Code Saturation Mutagenesis, 1st Author, 2018
- The transcriptome landscape of Prochlorococcus MED4 and the factors for stabilizing the core genome, 5th Author, 2014
- Transcriptome analysis of Chlamydomonas reinhardtii during the process of lipid accumulation, 2nd Author, 2013
- Book review of 'Enzyme engineering: Selective catalysts for applications in biotechnology, organic chemistry, and life science', 3rd Author
