Professor | Wei Ding | Asia Growth Partners

Name	Wei Ding
Contact Information	weiding@sjtu.edu.cn
Language ability	Chinese, English, German
Province	Shanghai

Name

Wei Ding

Contact Information

weiding@sjtu.edu.cn

Language ability

Chinese, English, German

Province

Shanghai

University/Lab Affiliation and Title	Shanghai Jiao Tong University
Faculty	Life Sciences
Academic Background & Achievements	2006-2010 PhD: Lanzhou University and Shanghai Institute of Organic Chemistry, CAS 2001-2005 Bachelor: Lanzhou University, School of Life Sciences
Work Experience	2019-present: Shanghai Jiao Tong University, School of Life Sciences and Technology, Special Research Fellow, Doctoral Supervisor 2013-2018: Lanzhou University, School of Life Sciences, Associate Professor, Master's Supervisor 2010-2012: Saarland University, Germany, Department of Pharmaceutical Biotechnology, Postdoctoral Researcher

University/Lab Affiliation and Title

Shanghai Jiao Tong University

Faculty

Life Sciences

Academic Background & Achievements

2006-2010 PhD: Lanzhou University and Shanghai Institute of Organic Chemistry, CAS
2001-2005 Bachelor: Lanzhou University, School of Life Sciences

Work Experience

2019-present: Shanghai Jiao Tong University, School of Life Sciences and Technology, Special Research Fellow, Doctoral Supervisor
2013-2018: Lanzhou University, School of Life Sciences, Associate Professor, Master's Supervisor
2010-2012: Saarland University, Germany, Department of Pharmaceutical Biotechnology, Postdoctoral Researcher

Areas of Focus	Biosynthesis mechanisms and synthetic biology of important bioactive natural products Discovery of active small molecules and efficient enzymes in extreme environmental microbes Diversity and directed evolution of enzyme catalysis mechanisms Biocatalysis and microbial industrial strains of important clinical drug intermediates
Publications	Convergent evolution of the Cys decarboxylases involved in aminovinyl-cysteine (AviCys) biosynthesis, Tianlv Mo, Dhanaraju Mandalapu, Hong Yuan, Wei Ding, Qi Zhang, 2019 Cypemycin Decarboxylase CypD Is Not Responsible for Aminovinyl–Cysteine (AviCys) Ring Formation, Wei Ding#, Ning Yuan#, Dhanaraju Mandalapu, Tianlu Mo, Suwei Dong, Qi Zhang, 2018 Substrate specificity of the cypemycin decarboxylase CypD, Wei Ding, Tianlu Mo, Dhanaraju Mandalapu, Qi Zhang, 2018 Radical SAM-dependent adenosylation catalyzed by L-tyrosine lyases, Yujie Wu, Runze Wu, Dhanaraju Mandalapu, Xinjian Ji, Tuo Chen, Wei Ding, Qi Zhang, 2018 Expanding the Chemistry of the Class C Radical SAM Methyltransferase NosN by Using an Allyl Analogue of SAM, Xinjian Ji, Dhanaraju Mandalapu, Jinduo Cheng, Wei Ding, Qi Zhang, 2018 Thioesterase-Mediated Synthesis of Teixobactin Analogues: Mechanism and Substrate Specificity, Dhanaraju Mandalapu, Xinjian Ji, Jinfeng Chen, Chuchu Guo, Wan-Qiu Liu, Wei Ding, Jiahai Zhou, Qi Zhang, 2018 Two Types of Threonine-Tagged Lipopeptides Synergize in Host Colonization by Pathogenic Burkholderia Species, Thongkongkaew Tawatchai, Ding Wei, Bratovanov Evgeni, Oueis Emilia, Garcia Altares Maria, Zaburannyi Nestor, Harmrolfs Kirsten, Zhang Youming, Scherlach Kirstin, Mueller Rolf, Hertweck Christian, 2018 Biosynthesis of the Nosiheptide Indole Side Ring Centers on a Cryptic Carrier Protein NosJ, Wei Ding, Wenjuan Ji, Yujie Wu, Runze Wu, Wan-Qiu Liu, Tianlu Mo, Junfeng Zhao, Xiaoyan Ma, Ping Xu, Boping Tang, Yi Yu, Qi Zhang, 2017 Catalytic Mechanism of the Class C radical S-Adenosylmethionine Methyltransferase, Wei Ding, Yongzhen Li, Junfeng Zhao, Xinjian Ji, Tianlu Mo, Haocheng Qianzhu, Zixin Deng, Yi Yu, Qi Zhang, 2017 Nucleoside-linked Shunt Products in the Reaction Catalyzed by the Class C Radical S-Adenosylmethionine Methyltransferase NosN, Wei Ding, Yujie Wu, Xinjian Ji, Haocheng Qianzhu, Fener Chen, Zixin Deng, Yi Yu, Qi Zhang*, 2017

Areas of Focus

Biosynthesis mechanisms and synthetic biology of important bioactive natural products
Discovery of active small molecules and efficient enzymes in extreme environmental microbes
Diversity and directed evolution of enzyme catalysis mechanisms
Biocatalysis and microbial industrial strains of important clinical drug intermediates

Publications

Convergent evolution of the Cys decarboxylases involved in aminovinyl-cysteine (AviCys) biosynthesis, Tianlv Mo, Dhanaraju Mandalapu, Hong Yuan, Wei Ding*, Qi Zhang*, 2019
Cypemycin Decarboxylase CypD Is Not Responsible for Aminovinyl–Cysteine (AviCys) Ring Formation, Wei Ding#, Ning Yuan#, Dhanaraju Mandalapu, Tianlu Mo, Suwei Dong*, Qi Zhang*, 2018
Substrate specificity of the cypemycin decarboxylase CypD, Wei Ding, Tianlu Mo, Dhanaraju Mandalapu, Qi Zhang*, 2018
Radical SAM-dependent adenosylation catalyzed by L-tyrosine lyases, Yujie Wu, Runze Wu, Dhanaraju Mandalapu, Xinjian Ji, Tuo Chen, Wei Ding, Qi Zhang, 2018
Expanding the Chemistry of the Class C Radical SAM Methyltransferase NosN by Using an Allyl Analogue of SAM, Xinjian Ji, Dhanaraju Mandalapu, Jinduo Cheng, Wei Ding, Qi Zhang*, 2018
Thioesterase-Mediated Synthesis of Teixobactin Analogues: Mechanism and Substrate Specificity, Dhanaraju Mandalapu, Xinjian Ji, Jinfeng Chen, Chuchu Guo, Wan-Qiu Liu, Wei Ding, Jiahai Zhou, Qi Zhang, 2018
Two Types of Threonine-Tagged Lipopeptides Synergize in Host Colonization by Pathogenic Burkholderia Species, Thongkongkaew Tawatchai, Ding Wei, Bratovanov Evgeni, Oueis Emilia, Garcia Altares Maria, Zaburannyi Nestor, Harmrolfs Kirsten, Zhang Youming, Scherlach Kirstin, Mueller Rolf*, Hertweck Christian*, 2018
Biosynthesis of the Nosiheptide Indole Side Ring Centers on a Cryptic Carrier Protein NosJ, Wei Ding, Wenjuan Ji, Yujie Wu, Runze Wu, Wan-Qiu Liu, Tianlu Mo, Junfeng Zhao, Xiaoyan Ma, Ping Xu, Boping Tang*, Yi Yu*, Qi Zhang*, 2017
Catalytic Mechanism of the Class C radical S-Adenosylmethionine Methyltransferase, Wei Ding, Yongzhen Li, Junfeng Zhao, Xinjian Ji, Tianlu Mo, Haocheng Qianzhu, Zixin Deng, Yi Yu, Qi Zhang*, 2017
Nucleoside-linked Shunt Products in the Reaction Catalyzed by the Class C Radical S-Adenosylmethionine Methyltransferase NosN, Wei Ding, Yujie Wu, Xinjian Ji, Haocheng Qianzhu, Fener Chen, Zixin Deng, Yi Yu, Qi Zhang*, 2017

Biosynthesis Synthetic Biology Bioactive Natural Products Extreme Environments Microbes Small Molecules Enzymes Catalysis Biocatalysis

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