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Zhe Sun
Life Science
University of Chinese Academy of Sciences
Tianjin
Language: Chinese, English
Bacterial Transcription Regulation
Gene Expression
Rna Polymerase
Sigma Factors
Transcriptional Pausing
Gre Factors
Synthetic Biology
Metabolic Pathways
Genetic Circuits
Microbial Metabolic Engineering
Areas of Focus
- Bacterial Transcription Regulation
- Synthetic Biology
- Microbial Metabolic Engineering
Work Experience
- 2021-12 to Present - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Researcher
- 2015-06 to 2021-10 - National Institutes of Health/National Cancer Institute, USA - Postdoctoral Researcher
- 2009-09 to 2022-05 - Shanghai Institute of Life Sciences, Chinese Academy of Sciences - Ph.D. Student
- 2005-09 to 2009-06 - Harbin Institute of Technology - Bachelor's Student
Academic Background & Achievements
- 2009-09 to 2022-05 Ph.D.: Shanghai Institute of Life Sciences, Chinese Academy of Sciences
- 2005-09 to 2009-06 Bachelor's: Harbin Institute of Technology
Publications
- Nascent RNA sequencing identifies a widespread sigma70-dependent pausing regulated by Gre factors in bacteria, First Author, 2021
- Escherichia coli σ38 promoters use two UP elements instead of a −35 element: resolution of a paradox and discovery that σ38 transcribes ribosomal promoters, Second Author, 2020
- Density of σ70 promoter-like sites in the intergenic regions dictates the redistribution of RNA polymerase during osmotic stress in Escherichia coli, First Author, 2019
- Imaging of transcription and replication in the bacterial chromosome with multicolor Three-Dimensional Superresolution Structured Illumination Microscopy, Third Author, 2018
- Extrachromosomal Nucleolus-Like Compartmentalization by a Plasmid-Borne Ribosomal RNA Operon and Its Role in Nucleoid Compaction, Second Author, 2018
- Nucleolus-like compartmentalization of the transcription machinery in fast-growing bacterial cells, Third Author, 2017
- Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria, Fourth Author, 2017
- A novel three-component system-based regulatory model for D-xylose sensing and transport in Clostridium beijerinckii, First Author, 2015
- Reconstruction of xylose utilization pathway and regulons in Firmicutes, Fourth Author, 2010
