Professor | 孙喆 | 数字化转型顾问

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Name

孙喆

Contact Information

sunzhe@tib.cas.cn

Language ability

中文, 英语

Province

天津

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2009-09 至 2022-05 博士: 中国科学院上海生命科学研究院 2005-09 至 2009-06 学士: 哈尔滨工业大学
Work Experience	2021-12 至今 - 中国科学院天津工业生物技术研究所 - 研究员 2015-06 至 2021-10 - 美国国立卫生研究院/国家癌症研究所 - 博士后 2009-09 至 2022-05 - 中国科学院上海生命科学研究院 - 博士生 2005-09 至 2009-06 - 哈尔滨工业大学 - 学士生

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

Work Experience

Areas of Focus	细菌转录调控合成生物学微生物代谢工程
Publications	Nascent RNA sequencing identifies a widespread sigma70-dependent pausing regulated by Gre factors in bacteria, 第一作者, 2021 Escherichia coli σ38 promoters use two UP elements instead of a −35 element: resolution of a paradox and discovery that σ38 transcribes ribosomal promoters, 第二作者, 2020 Density of σ70 promoter-like sites in the intergenic regions dictates the redistribution of RNA polymerase during osmotic stress in Escherichia coli, 第一作者, 2019 Imaging of transcription and replication in the bacterial chromosome with multicolor Three-Dimensional Superresolution Structured Illumination Microscopy, 第三作者, 2018 Extrachromosomal Nucleolus-Like Compartmentalization by a Plasmid-Borne Ribosomal RNA Operon and Its Role in Nucleoid Compaction, 第二作者, 2018 Nucleolus-like compartmentalization of the transcription machinery in fast-growing bacterial cells, 第三作者, 2017 Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria, 第四作者, 2017 A novel three-component system-based regulatory model for D-xylose sensing and transport in Clostridium beijerinckii, 第一作者, 2015 Reconstruction of xylose utilization pathway and regulons in Firmicutes, 第四作者, 2010

Areas of Focus

细菌转录调控
合成生物学
微生物代谢工程

Publications

Nascent RNA sequencing identifies a widespread sigma70-dependent pausing regulated by Gre factors in bacteria, 第一作者, 2021
Escherichia coli σ38 promoters use two UP elements instead of a −35 element: resolution of a paradox and discovery that σ38 transcribes ribosomal promoters, 第二作者, 2020
Density of σ70 promoter-like sites in the intergenic regions dictates the redistribution of RNA polymerase during osmotic stress in Escherichia coli, 第一作者, 2019
Imaging of transcription and replication in the bacterial chromosome with multicolor Three-Dimensional Superresolution Structured Illumination Microscopy, 第三作者, 2018
Extrachromosomal Nucleolus-Like Compartmentalization by a Plasmid-Borne Ribosomal RNA Operon and Its Role in Nucleoid Compaction, 第二作者, 2018
Nucleolus-like compartmentalization of the transcription machinery in fast-growing bacterial cells, 第三作者, 2017
Molecular mechanism of environmental d-xylose perception by a XylFII-LytS complex in bacteria, 第四作者, 2017
A novel three-component system-based regulatory model for D-xylose sensing and transport in Clostridium beijerinckii, 第一作者, 2015
Reconstruction of xylose utilization pathway and regulons in Firmicutes, 第四作者, 2010

细菌转录调控基因表达 Rna聚合酶 Sigma因子转录暂停 Gre因子合成生物学代谢途径遗传电路微生物代谢工程

张余 - 中国科学院大学

Area of Focus
转录 | Rna聚合酶 | 基因表达 | Dna修复 | 甲基化 | 噬菌体 | 免疫 | 叶绿体 | 酶 | 代谢途径

胡洪波 - 上海交通大学

张雪洪 - 上海交通大学

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