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Qinmiao Sun
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
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Natural Immunity Immune Response Innate Immunity Pathogen Recognition Immune Signaling Cytokines Inflammation Antiviral Defense Immune Regulation Host-Pathogen Interaction Stem Cells Pluripotency Cell Differentiation Regenerative Medicine Stem Cell Therapy Cell Reprogramming Tissue Engineering Stem Cell Niche Stem Cell Biology Stem Cell Research Cancer Biology Tumorigenesis Oncogenes Tumor Suppressors Cancer Metastasis Cancer Therapy Cancer Immunology Cancer Genetics Cancer Cell Signaling Cancer Biomarkers
Areas of Focus
  • Natural Immunity
  • Stem Cells
  • Cancer Biology
Work Experience
  • 2015-03~Present - University of Chinese Academy of Sciences - Researcher
  • 2007-05~Present - Institute of Zoology, Chinese Academy of Sciences - Researcher
  • 2006-01~2007-12 - University of Texas Southwestern Medical Center - Lecturer
  • 2001-12~2005-12 - University of Texas Southwestern Medical Center - Postdoctoral
  • 2000-02~2000-11 - University of Kentucky - Postdoctoral
  • 1996-09~1999-07 - Institute of Botany, Chinese Academy of Sciences - PhD
  • 1993-09~1996-07 - Shandong Agricultural University - Master's
  • 1989-09~1993-07 - Shandong Agricultural University - Bachelor's
Academic Background & Achievements
  • 1996-09--1999-07 PhD: Institute of Botany, Chinese Academy of Sciences
  • 1993-09--1996-07 Master's: Shandong Agricultural University
  • 1989-09--1993-07 Bachelor's: Shandong Agricultural University
Publications
  • PTK2B promotes TBK1 and STING oligomerization and enhances the STING-TBK1 signaling, NATURE COMMUNICATIONS, 2023
  • Ku proteins promote DNA binding and condensation of cyclic GMP-AMP synthase, CELL REPORTS, 2022
  • PCBP2 maintains antiviral signaling homeostasis by regulating cGAS enzymatic activity via antagonizing its condensation, NATURE COMMUNICATIONS, 2022
  • Dynamic FMR1 granule phase switch instructed by m6A modification contributes to maternal RNA decay, NATURE COMMUNICATIONS, 2022
  • KIZ/GM114 Balances the NF-κB Signaling by Antagonizing the Association of TRAF2/6 With Their Upstream Adaptors, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022
  • RNA-Seq analysis of gene expression profile of human macrophages infected by vaccinia virus, 微生物学报, 2021
  • ZDHHC11 Positively Regulates NF-κB Activation by Enhancing TRAF6 Oligomerization, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2021
  • USP27X negatively regulates antiviral signaling by deubiquitinating RIG-I, PLOS PATHOGENS, 2020
  • LC Domain-Mediated Coalescence Is Essential for Otu Enzymatic Activity to Extend Drosophila Lifespan, MOLECULAR CELL, 2019
  • 6mA-DNA-binding factor Jumu controls maternal-to-zygotic transition upstream of Zelda, NATURE COMMUNICATIONS, 2019
  • Parkin negatively regulates the antiviral signaling pathway by targeting TRAF3 for degradation, JOURNAL OF BIOLOGICAL CHEMISTRY, 2018
  • Partial loss of psychiatric risk gene miR-137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a, NATURE NEUROSCIENCE, 2018
  • Bam-dependent deubiquitinase complex can disrupt germ-line stem cell maintenance by targeting cyclin A, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017
  • Membrane Targeting of Inhibitory Smads Through Palmitoylation Controls TGF-β/BMP Signaling, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017
  • Syndecan-4 negatively regulates antiviral signaling by mediating RIG-I deubiquitination via CYLD, NATURE COMMUNICATIONS, 2016
  • Identification of miRNomes Reveals ssc-miR-30d-R_1 as a Potential Therapeutic Target for PRRS Viral Infection, SCIENTIFIC REPORTS, 2016
  • MAVS Maintains Mitochondrial Homeostasis via Autophagy, CELL DISCOVERY, 2016
  • Critical POU Domain Residues Confer Oct4 Uniqueness in Somatic Cell Reprogramming, SCIENTIFIC REPORTS, 2016
  • PPM1A Regulates Antiviral Signaling by Antagonizing TBK1-Mediated STING Phosphorylation and Aggregation, PUBLIC LIBRARY OF SCIENCE, 2015
  • N6-Methyladenine Functions as a Potential Epigenetic Mark in Eukaryotes, BIOESSAYS, 2015
  • Stucturally Diverse Sesquiterpenes Produced by a Chinese Tibet Fungus Stereum hirsutum and Their Cytotoxic and Immunosuppressant Activities, ORGANIC LETTERS, 2015
  • Cell-surface localization of Pellino antagonizes Toll-mediated innate immune signaling by controlling MyD88 turnover in Drosophila, NATURE COMMUNICATIONS, 2014
  • Coordination of Engineered Factors with TET1/2 Promotes Early-Stage Epigenetic Modification during Somatic Cell Reprogramming, STEM CELL REPORTS, 2014
  • Genome-Wide Loss of 5-hmC Is a Novel Epigenetic Feature of Huntingtons Disease, HUMAN MOLECULAR GENETICS, 2013
  • Dysregulation of Mitochondrial Calcium Signaling and Superoxide Flashes Cause Mitochondrial Genomic DNA Damage in Huntington Disease, JOURNAL OF BIOLOGICAL CHEMISTRY, 2013
  • COX5B Regulates MAVS-mediated Antiviral Signaling through Interaction with ATG5 and Repressing ROS Production, PLOS PATHOGENS, 2012
  • The Fused/Smurf Complex Controls the Fate of Drosophila Germline Stem Cells by Generating a Gradient BMP Response, CELL, 2010
  • Murine Gamma-Herpesvirus 68 Hijacks MAVS and IKK beta to Initiate Lytic Replication, PLOS PATHOGENS, 2010
  • 光照和温度对豌豆Lhcb2基因表达的影响, 植物学报:英文版, 2000
  • 豌豆Lhcb2基因在大肠杆菌中的高效表达及其表达产物与色素的重组, 中国科学(C辑), 2000
  • 高等植物光系统II捕光色素蛋白复合体结构与功能研究的新进展, 植物学通报, 2000
  • 豌豆Lhcb2 基因的克隆、表达、功能分析及其克隆化蛋白与色素体外重组系统的建立, Cloning, Expression, Functional Analysis of Pea Lhcb2 Gene and Construction of Reconstitution System with its Protein Overexpressed in E. coli and Pigment Vitro, 1999
  • 纯化膜蛋白质复合体Cytb6f的新方法, 植物学报:英文版, 1998
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