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Jibin Sun
Life Science
University of Chinese Academy of Sciences
Tianjin
Language: Chinese, German, English
Systems Biology
Industrial Microorganisms
Omics
Synthetic Biology
Industrial Strains
Microbial Engineering
Biotechnology
Genomics
Proteomics
Metabolomics
Areas of Focus
- Systems Biology of Industrial Microorganisms
- Omics Technologies
- Synthetic Biotechnology
- Design and Development of Industrial Strains
Work Experience
- 2020-08~Present - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Director of Systems Biology Center
- 2012-11~2023-11 - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Deputy Director
- 2008-03~Present - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Researcher
- 2004-10~2008-03 - Helmholtz Center for Infection Research, Germany - Postdoctoral Researcher
- 1996-07~2000-09 - State Key Laboratory of Microbial Technology, Shandong University - Lecturer
Academic Background & Achievements
- 2000-10--2004-10 PhD: Technische Universität Braunschweig/German National Research Center for Biotechnology (GBF)
- 1993-09--1996-07 Master's: Shandong University
- 1989-09--1993-07 Bachelor's: Shandong University
Publications
- Automated and integrated ultrahigh throughput industrial strain screening enabled by acoustic-droplet-ejection mass spectrometry, Jibin Sun, 2024
- Engineering allosteric inhibition of homoserine dehydrogenase by semi-rational saturation mutagenesis screening, Jibin Sun, 2024
- Novel 15N Metabolic Labeling-Based Large-Scale Absolute Quantitative Proteomics Method for Corynebacterium glutamicum, Jibin Sun, 2023
- Advances of development and application amino acid biosensors, Jibin Sun, 2023
- Systems metabolic engineering of Escherichia coli for hyper-production of 5-aminolevulinic acid, Jibin Sun, 2023
- Sustainable and high-level microbial production of plant hemoglobin in Corynebacterium glutamicum, Jibin Sun, 2023
- Genome-scale CRISPRi screening: A powerful tool in engineering microbiology, Jibin Sun, 2023
- Directed evolution of a neutrophilic and mesophilic methanol dehydrogenase based on high-throughput and accurate measurement of formaldehyde, Jibin Sun, 2023
- Genome-wide transcription landscape of citric acid producing Aspergillus niger in response to glucose gradient, Jibin Sun, 2023
- Engineering of the DNA replication and repair machinery to develop binary mutators for rapid genome evolution of Corynebacterium glutamicum, Jibin Sun, 2023
- Development of a growth-coupled selection platform for directed evolution of heme biosynthetic enzymes in Corynebacterium glutamicum, Jibin Sun, 2023
- Upgrading microbial strains for fermentation industry, Jibin Sun, 2022
- Protocol for gene characterization in Aspergillus niger using 5S rRNA-CRISPR-Cas9-mediated Tet-on inducible promoter exchange, Jibin Sun, 2022
- A Library of Aspergillus niger Chassis Strains for Morphology Engineering Connects Strain Fitness and Filamentous Growth With Submerged Macromorphology, Jibin Sun, 2022
- Evaluation of Aspergillus niger Six Constitutive Strong Promoters by Fluorescent-Auxotrophic Selection Coupled with Flow Cytometry: A Case for Citric Acid Production, Jibin Sun, 2022
- Innovation of key technologies in fermentative production of L-glutamate and industrial application, Jibin Sun, 2022
- Engineering synthetic auxotrophs for growth-coupled directed protein evolution, Jibin Sun, 2022
- Crystal structure of 5-Aminolevulinate synthase HemA from Rhodopseudomonas palustris presents multiple conformations, Jibin Sun, 2022
- Quantitative phenotypic screens of Aspergillus niger mutants in solid and liquid culture, Jibin Sun, 2022
- Engineering of the Translesion DNA Synthesis Pathway Enables Controllable C-to-G and C-to-A Base Editing in Corynebacterium glutamicum, Jibin Sun, 2022
- Directed evolution of linker helix as an efficient strategy for engineering LysR-type transcriptional regulators as whole-cell biosensors, Jibin Sun, 2022
- Developing Synthetic Methylotrophs by Metabolic Engineering-Guided Adaptive Laboratory Evolution, Jibin Sun, 2022
- Comprehensively dissecting the hub regulation of PkaC on high-productivity and pellet macromorphology in citric acid producing Aspergillus niger, Jibin Sun, 2022
- CRISPR-assisted rational flux-tuning and arrayed CRISPRi screening of an L-proline exporter for L-proline hyperproduction, Jibin Sun, 2022
- Quantitative phenotypic screens of Aspergillus niger mutants in solid and liquid culture, Jibin Sun, 2022
- Construction and application of a synthetic promoter library for Corynebacterium glutamicum, Jibin Sun, 2022
- Regulations of Small-molecules Metabolites on Hexokinase and Pyruvate Kinase in Aspergillus niger, Jibin Sun, 2021
- Development of a Hyperosmotic Stress Inducible Gene Expression System by Engineering the MtrA/MtrB-Dependent NCgl1418 Promoter in Corynebacterium glutamicum, Jibin Sun, 2021
- Isoleucyl-tRNA synthetase mutant based whole-cell biosensor for high-throughput selection of isoleucine overproducers, Jibin Sun, 2021
- Methanol dehydrogenase, a key enzyme of one-carbon metabolism: a review, Jibin Sun, 2021
- Turning Inside Out: Filamentous Fungal Secretion and Its Applications in Biotechnology, Agriculture, and the Clinic, Jibin Sun, 2021
- Transcriptome analysis reveals the roles of nitrogen metabolism and sedoheptulose bisphosphatase pathway in methanol-dependent growth of Corynebacterium glutamicum, Jibin Sun, 2021
- In-situ generation of large numbers of genetic combinations for metabolic reprogramming via CRISPR-guided base editing, Jibin Sun, 2021
- Promoting Lignin Valorization by Coping with Toxic C1 Byproducts, Jibin Sun, 2021
- CRISPR/Cas-based genome editing in Aspergillus niger, Jibin Sun, 2021
- Microbial Base Editing: A Powerful Emerging Technology for Microbial Genome Engineering, Jibin Sun, 2021
- Advances and perspective on bioproduction of 5-aminolevulinic acid, Jibin Sun, 2021
- Microbial Base Editing: A Powerful Emerging Technology for Microbial Genome Engineering, Jibin Sun, 2020
- Regulation and Guidance for Marketing of Food Ingredients from Biomanufacturing and Policy Suggestions for China, Jibin Sun, 2020
- Disruption or reduced expression of the orotidine-5′-decarboxylase gene pyrG increases citric acid production: a new discovery during recyclable genome editing in Aspergillus n
Awards
- Inner Mongolia Autonomous Region Science and Technology Progress Award (2020): First Prize
- New Technology and Industrial Application of Green Manufacturing of Citric Acid (2019): Special Prize
- Creation and Application of New Generation Industrial Strains (2019): Institute Level
- Special Researcher of the Chinese Academy of Sciences (2016): Institute Level
- State Council Government Special Allowance (2016): National Level
- Innovation of Lysine Industrial Strains (2014): Ministry Level
- Industry-University-Research Cooperation Promotion Award (2014): Ministry Level
- GBF Foundation Excellent Doctoral Dissertation Award (2005): Other
- National Science and Technology Award for Technological Invention (2005): Second Prize
- DAAD Scholarship (2000): Other
