Professor | Xinyang Song | Asia Growth Partners

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Name	Xinyang Song
Contact Information	xinyang.song@sibcb.ac.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Xinyang Song

Contact Information

xinyang.song@sibcb.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2007-09--2014-07 Ph.D. in Science: University of Chinese Academy of Sciences 2003-09--2007-07 Bachelor's in Science: China Pharmaceutical University
Work Experience	2016-06~2021-05 - Harvard Medical School - Postdoctoral Researcher 2007-09~2014-07 - University of Chinese Academy of Sciences - Ph.D. Student 2003-09~2007-07 - China Pharmaceutical University - Bachelor's Student
Awards	Outstanding Doctoral Dissertation of the Chinese Academy of Sciences (2015): First Prize President's Special Award of the Chinese Academy of Sciences (2014): First Prize Chinese Representative at the 64th Lindau Nobel Laureate Meeting (2014): First Prize Wu Rui Scholarship (2013): First Prize Johnson & Johnson Asia Outstanding Life Science Graduate Thesis Award (2012): Second Prize National Graduate Scholarship (2012): First Prize President's Excellence Award of the Chinese Academy of Sciences (2012): First Prize

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2007-09--2014-07 Ph.D. in Science: University of Chinese Academy of Sciences
2003-09--2007-07 Bachelor's in Science: China Pharmaceutical University

Work Experience

2016-06~2021-05 - Harvard Medical School - Postdoctoral Researcher
2007-09~2014-07 - University of Chinese Academy of Sciences - Ph.D. Student
2003-09~2007-07 - China Pharmaceutical University - Bachelor's Student

Awards

Outstanding Doctoral Dissertation of the Chinese Academy of Sciences (2015): First Prize
President's Special Award of the Chinese Academy of Sciences (2014): First Prize
Chinese Representative at the 64th Lindau Nobel Laureate Meeting (2014): First Prize
Wu Rui Scholarship (2013): First Prize
Johnson & Johnson Asia Outstanding Life Science Graduate Thesis Award (2012): Second Prize
National Graduate Scholarship (2012): First Prize
President's Excellence Award of the Chinese Academy of Sciences (2012): First Prize

Areas of Focus	Mucosal Immunology Microbiome
Publications	Gut complement induced by the microbiota combats pathogens and spares commensals, Cell, 2024 Intestinal epithelial dopamine receptor signaling drives sex-specific disease exacerbation in a mouse model of multiple sclerosis, Immunity, 2023 Gut microbial fatty acid isomerization modulates intraepithelial T cells, Nature, 2023 The impact of lung microbiota dysbiosis on inflammation, IMMUNOLOGY, 2020 Microbial bile acid metabolites modulate gut ROR gamma(+) regulatory T cell homeostasis, NATURE, 2020 Microbiota-targeted maternal antibodies protect neonates from enteric infection, NATURE, 2020 STAT4 activation by leukemia inhibitory factor confers a therapeutic effect on intestinal inflammation, The EMBO Journal, 2019 Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles, IMMUNITY, 2019 USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein, JOURNAL OF EXPERIMENTAL MEDICINE, 2018 c-Jun N-terminal kinases differentially regulate TNF- and TLRs-mediated necroptosis through their kinase-dependent and -independent activities, CELL DEATH AND DISEASE, 2018 Antigen-specific CD8(+) T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin, NATURE COMMUNICATIONS, 2017 FGF2 cooperates with IL-17 to promote autoimmune inflammation, SCIENTIFIC REPORTS, 2017 Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage, IMMUNITY, 2015 Intestinal microbiota mining: a Th17/Treg cell perspective, European Journal of BioMedical Research, 2015 Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis, IMMUNITY, 2014 Peli1 sets the CNS on fire, NATURE MEDICINE, 2013 The activation and regulation of IL-17 receptor mediated signaling, CYTOKINE, 2013 IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases, CELLULAR SIGNALLING, 2013 The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-β, Nature Medicine, 2012 IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens, NATURE IMMUNOLOGY, 2011 The roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunity, CELLULAR AND MOLECULAR IMMUNOLOGY, 2011 Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling, THE JOURNAL OF EXPERIMENTAL MEDICINE, 2011

Areas of Focus

Mucosal Immunology
Microbiome

Publications

Gut complement induced by the microbiota combats pathogens and spares commensals, Cell, 2024
Intestinal epithelial dopamine receptor signaling drives sex-specific disease exacerbation in a mouse model of multiple sclerosis, Immunity, 2023
Gut microbial fatty acid isomerization modulates intraepithelial T cells, Nature, 2023
The impact of lung microbiota dysbiosis on inflammation, IMMUNOLOGY, 2020
Microbial bile acid metabolites modulate gut ROR gamma(+) regulatory T cell homeostasis, NATURE, 2020
Microbiota-targeted maternal antibodies protect neonates from enteric infection, NATURE, 2020
STAT4 activation by leukemia inhibitory factor confers a therapeutic effect on intestinal inflammation, The EMBO Journal, 2019
Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles, IMMUNITY, 2019
USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein, JOURNAL OF EXPERIMENTAL MEDICINE, 2018
c-Jun N-terminal kinases differentially regulate TNF- and TLRs-mediated necroptosis through their kinase-dependent and -independent activities, CELL DEATH AND DISEASE, 2018
Antigen-specific CD8(+) T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin, NATURE COMMUNICATIONS, 2017
FGF2 cooperates with IL-17 to promote autoimmune inflammation, SCIENTIFIC REPORTS, 2017
Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage, IMMUNITY, 2015
Intestinal microbiota mining: a Th17/Treg cell perspective, European Journal of BioMedical Research, 2015
Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis, IMMUNITY, 2014
Peli1 sets the CNS on fire, NATURE MEDICINE, 2013
The activation and regulation of IL-17 receptor mediated signaling, CYTOKINE, 2013
IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases, CELLULAR SIGNALLING, 2013
The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-β, Nature Medicine, 2012
IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens, NATURE IMMUNOLOGY, 2011
The roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunity, CELLULAR AND MOLECULAR IMMUNOLOGY, 2011
Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling, THE JOURNAL OF EXPERIMENTAL MEDICINE, 2011

Mucosal Immunology Microbiome Gut Health Immune Response Pathogens Commensals Inflammation T Cells Microbial Metabolites Disease Modulation

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