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Xinyang Song
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
Mucosal Immunology
Microbiome
Gut Health
Immune Response
Pathogens
Commensals
Inflammation
T Cells
Microbial Metabolites
Disease Modulation
Areas of Focus
- Mucosal Immunology
- Microbiome
Work Experience
- 2016-06~2021-05 - Harvard Medical School - Postdoctoral Researcher
- 2007-09~2014-07 - University of Chinese Academy of Sciences - Ph.D. Student
- 2003-09~2007-07 - China Pharmaceutical University - Bachelor's Student
Academic Background & Achievements
- 2007-09--2014-07 Ph.D. in Science: University of Chinese Academy of Sciences
- 2003-09--2007-07 Bachelor's in Science: China Pharmaceutical University
Publications
- Gut complement induced by the microbiota combats pathogens and spares commensals, Cell, 2024
- Intestinal epithelial dopamine receptor signaling drives sex-specific disease exacerbation in a mouse model of multiple sclerosis, Immunity, 2023
- Gut microbial fatty acid isomerization modulates intraepithelial T cells, Nature, 2023
- The impact of lung microbiota dysbiosis on inflammation, IMMUNOLOGY, 2020
- Microbial bile acid metabolites modulate gut ROR gamma(+) regulatory T cell homeostasis, NATURE, 2020
- Microbiota-targeted maternal antibodies protect neonates from enteric infection, NATURE, 2020
- STAT4 activation by leukemia inhibitory factor confers a therapeutic effect on intestinal inflammation, The EMBO Journal, 2019
- Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles, IMMUNITY, 2019
- USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein, JOURNAL OF EXPERIMENTAL MEDICINE, 2018
- c-Jun N-terminal kinases differentially regulate TNF- and TLRs-mediated necroptosis through their kinase-dependent and -independent activities, CELL DEATH AND DISEASE, 2018
- Antigen-specific CD8(+) T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin, NATURE COMMUNICATIONS, 2017
- FGF2 cooperates with IL-17 to promote autoimmune inflammation, SCIENTIFIC REPORTS, 2017
- Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage, IMMUNITY, 2015
- Intestinal microbiota mining: a Th17/Treg cell perspective, European Journal of BioMedical Research, 2015
- Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis, IMMUNITY, 2014
- Peli1 sets the CNS on fire, NATURE MEDICINE, 2013
- The activation and regulation of IL-17 receptor mediated signaling, CYTOKINE, 2013
- IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases, CELLULAR SIGNALLING, 2013
- The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-β, Nature Medicine, 2012
- IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens, NATURE IMMUNOLOGY, 2011
- The roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunity, CELLULAR AND MOLECULAR IMMUNOLOGY, 2011
- Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling, THE JOURNAL OF EXPERIMENTAL MEDICINE, 2011
Awards
- Outstanding Doctoral Dissertation of the Chinese Academy of Sciences (2015): First Prize
- President's Special Award of the Chinese Academy of Sciences (2014): First Prize
- Chinese Representative at the 64th Lindau Nobel Laureate Meeting (2014): First Prize
- Wu Rui Scholarship (2013): First Prize
- Johnson & Johnson Asia Outstanding Life Science Graduate Thesis Award (2012): Second Prize
- National Graduate Scholarship (2012): First Prize
- President's Excellence Award of the Chinese Academy of Sciences (2012): First Prize
