Professor | 宋昕阳 | 数字化转型顾问

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Name	宋昕阳
Contact Information	xinyang.song@sibcb.ac.cn
Language ability	中文, 英语
Province	上海

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Name

宋昕阳

Contact Information

xinyang.song@sibcb.ac.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2007-09--2014-07 理学博士: 中国科学院大学 2003-09--2007-07 理学学士: 中国药科大学
Work Experience	2016-06~2021-05 - 哈佛医学院 - 博士后 2007-09~2014-07 - 中国科学院大学 - 理学博士 2003-09~2007-07 - 中国药科大学 - 理学学士
Awards	中国科学院优秀博士学位论文 (2015): 一等奖中国科学院院长特别奖 (2014): 一等奖第六十四届德国林道诺贝尔奖得主大会中方博士研究生代表 (2014): 一等奖吴瑞奖学金 (2013): 一等奖强生亚洲优秀生命科技研究生论文奖 (2012): 二等奖研究生国家奖学金获得者 (2012): 一等奖中国科学院院长优秀奖 (2012): 一等奖

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2007-09--2014-07 理学博士: 中国科学院大学
2003-09--2007-07 理学学士: 中国药科大学

Work Experience

2016-06~2021-05 - 哈佛医学院 - 博士后
2007-09~2014-07 - 中国科学院大学 - 理学博士
2003-09~2007-07 - 中国药科大学 - 理学学士

Awards

中国科学院优秀博士学位论文 (2015): 一等奖
中国科学院院长特别奖 (2014): 一等奖
第六十四届德国林道诺贝尔奖得主大会中方博士研究生代表 (2014): 一等奖
吴瑞奖学金 (2013): 一等奖
强生亚洲优秀生命科技研究生论文奖 (2012): 二等奖
研究生国家奖学金获得者 (2012): 一等奖
中国科学院院长优秀奖 (2012): 一等奖

Areas of Focus	黏膜免疫学微生物组学
Publications	Gut complement induced by the microbiota combats pathogens and spares commensals, Cell, 2024 Intestinal epithelial dopamine receptor signaling drives sex-specific disease exacerbation in a mouse model of multiple sclerosis, Immunity, 2023 Gut microbial fatty acid isomerization modulates intraepithelial T cells, Nature, 2023 The impact of lung microbiota dysbiosis on inflammation, IMMUNOLOGY, 2020 Microbial bile acid metabolites modulate gut ROR gamma(+) regulatory T cell homeostasis, NATURE, 2020 Microbiota-targeted maternal antibodies protect neonates from enteric infection, NATURE, 2020 STAT4 activation by leukemia inhibitory factor confers a therapeutic effect on intestinal inflammation, The EMBO Journal, 2019 Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles, IMMUNITY, 2019 USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein, JOURNAL OF EXPERIMENTAL MEDICINE, 2018 c-Jun N-terminal kinases differentially regulate TNF- and TLRs-mediated necroptosis through their kinase-dependent and -independent activities, CELL DEATH AND DISEASE, 2018 Antigen-specific CD8(+) T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin, NATURE COMMUNICATIONS, 2017 FGF2 cooperates with IL-17 to promote autoimmune inflammation, SCIENTIFIC REPORTS, 2017 Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage, IMMUNITY, 2015 Intestinal microbiota mining: a Th17/Treg cell perspective, European Journal of BioMedical Research, 2015 Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis, IMMUNITY, 2014 Peli1 sets the CNS on fire, NATURE MEDICINE, 2013 The activation and regulation of IL-17 receptor mediated signaling, CYTOKINE, 2013 IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases, CELLULAR SIGNALLING, 2013 The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-β, Nature Medicine, 2012 IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens, NATURE IMMUNOLOGY, 2011 The roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunity, CELLULAR AND MOLECULAR IMMUNOLOGY, 2011 Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling, THE JOURNAL OF EXPERIMENTAL MEDICINE, 2011

Areas of Focus

黏膜免疫学
微生物组学

Publications

Gut complement induced by the microbiota combats pathogens and spares commensals, Cell, 2024
Intestinal epithelial dopamine receptor signaling drives sex-specific disease exacerbation in a mouse model of multiple sclerosis, Immunity, 2023
Gut microbial fatty acid isomerization modulates intraepithelial T cells, Nature, 2023
The impact of lung microbiota dysbiosis on inflammation, IMMUNOLOGY, 2020
Microbial bile acid metabolites modulate gut ROR gamma(+) regulatory T cell homeostasis, NATURE, 2020
Microbiota-targeted maternal antibodies protect neonates from enteric infection, NATURE, 2020
STAT4 activation by leukemia inhibitory factor confers a therapeutic effect on intestinal inflammation, The EMBO Journal, 2019
Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles, IMMUNITY, 2019
USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein, JOURNAL OF EXPERIMENTAL MEDICINE, 2018
c-Jun N-terminal kinases differentially regulate TNF- and TLRs-mediated necroptosis through their kinase-dependent and -independent activities, CELL DEATH AND DISEASE, 2018
Antigen-specific CD8(+) T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin, NATURE COMMUNICATIONS, 2017
FGF2 cooperates with IL-17 to promote autoimmune inflammation, SCIENTIFIC REPORTS, 2017
Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage, IMMUNITY, 2015
Intestinal microbiota mining: a Th17/Treg cell perspective, European Journal of BioMedical Research, 2015
Alterations in the Microbiota Drive Interleukin-17C Production from Intestinal Epithelial Cells to Promote Tumorigenesis, IMMUNITY, 2014
Peli1 sets the CNS on fire, NATURE MEDICINE, 2013
The activation and regulation of IL-17 receptor mediated signaling, CYTOKINE, 2013
IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases, CELLULAR SIGNALLING, 2013
The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-β, Nature Medicine, 2012
IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens, NATURE IMMUNOLOGY, 2011
The roles and functional mechanisms of interleukin-17 family cytokines in mucosal immunity, CELLULAR AND MOLECULAR IMMUNOLOGY, 2011
Modulation of experimental autoimmune encephalomyelitis through TRAF3-mediated suppression of interleukin 17 receptor signaling, THE JOURNAL OF EXPERIMENTAL MEDICINE, 2011

黏膜免疫学微生物组学肠道健康免疫反应病原体共生菌炎症 T细胞微生物代谢物疾病调节

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