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Yidong Shen
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English, German
Aging
Age-Related Diseases
Cancer
Cardiovascular Diseases
Neurodegenerative Diseases
Obesity
Longevity Pathways
Dietary Restriction
Transcription Factors
Model Organisms
Areas of Focus
- Mechanisms of Aging and Age-Related Diseases
Work Experience
- 2014-05 to Present - Shanghai Institute of Life Sciences, Chinese Academy of Sciences - Researcher
- 2009-09 to 2014-04 - Max Planck Institute for Biology of Ageing, Germany - Postdoctoral Researcher
- 2009-04 to 2009-08 - Baylor College of Medicine, USA - Postdoctoral Researcher
- 2008-02 to 2009-03 - Shanghai Institute of Life Sciences, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
- 2002-09 to 2008-01 PhD: Shanghai Institute of Life Sciences, Chinese Academy of Sciences
- 1998-09 to 2002-07 Bachelor: Fudan University
Publications
- Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans, Xueqing Wang, Quanlong Jiang, Hongdao Zhang, Zhidong He, Yuanyuan Song, Yifan Chen, Na Tang, Yifei Zhou, Yiping Li, Adam Antebi, Ligang Wu, JingDong J Han, Yidong Shen, 2024
- Ageing induces tissue-specific transcriptomic changes in Caenorhabditis elegans, Wang, Xueqing, Jiang, Quanlong, Song, Yuanyuan, He, Zhidong, Zhang, Hongdao, Song, Mengjiao, Zhang, Xiaona, Dai, Yumin, Karalay, Oezlem, Dieterich, Christoph, Antebi, Adam, Wu, Ligang, Han, JingDong J, Shen, Yidong, 2022
- The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing, Yincong Zhang, Xiaona Zhang, Yumin Dai, Mengjiao Song, Yifei Zhou, Jun Zhou, Xiumin Yan, Yidong Shen, 2021
- A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing, Yifei Zhou, Xueqing Wang, Mengjiao Song, Zhidong He, Guizhong Cui, Guangdun Peng, Christoph Dieterich, Adam Antebi, Naihe Jing, Yidong Shen, 2019
- A microRNA switch controls dietary restriction-induced longevity through Wnt signaling, Xu, Yunpeng, He, Zhidong, Song, Mengjiao, Zhou, Yifei, Shen, Yidong, 2019
- 细胞“天线”——纤毛研究的前世今生, 张银聪, 鄢秀敏, 沈义栋, 2019
- Dietary Restriction Induced Longevity Is Mediated by Nuclear Receptor NHR-62 in Caenorhabditis elegans, Heestand, Bree N, Shen, Yidong, Liu, Wei, Magner, Daniel B, Storm, Nadia, Meharg, Caroline, Habermann, Bianca, Antebi, Adam, 2013
- The NHR-8 Nuclear Receptor Regulates Cholesterol and Bile Acid Homeostasis in C. elegans, Magner, Daniel B, Wollam, Joshua, Shen, Yidong, Hoppe, Caroline, Li, Dongling, Latza, Christian, Rottiers, Veerle, Hutter, Harald, Antebi, Adam, 2013
- A Steroid Receptor-MicroRNA Switch Regulates Life Span in Response to Signals from the Gonad, Shen, Yidong, Wollam, Joshua, Magner, Daniel, Karalay, Oezlem, Antebi, Adam, 2012
- A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity, Wollam, Joshua, Magner, Daniel B, Magomedova, Lilia, Rass, Elisabeth, Shen, Yidong, Rottiers, Veerle, Habermann, Bianca, Cummins, Carolyn L, Antebi, Adam, 2012
- miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics, Cao, Jingli, Shen, Yidong, Zhu, Lei, Xu, Yanan, Zhou, Yizhuo, Wu, Zhili, Li, Yiping, Yan, Xiumin, Zhu, Xueliang, 2012
- The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity, Wollam, Joshua, Magomedova, Lilia, Magner, Daniel B, Shen, Yidong, Rottiers, Veerle, Motola, Daniel L, Mangelsdorf, David J, Cummins, Carolyn L, Antebi, Adam, 2011
- Live Show of Rho GTPases in Cell Migration, Yan, Xiumin, Shen, Yidong, Zhu, Xueliang, 2010
- Nudel Promotes Axonal Lysosome Clearance and Endo-lysosome Formation via Dynein-Mediated Transport, Zhang, Qiangge, Wang, Fubin, Cao, Jingli, Shen, Yidong, Huang, Qiongping, Bao, Lan, Zhu, Xueliang, 2009
- Nudel binds Cdc42GAP to modulate Cdc42 activity at the leading edge of migrating cells, Shen, Yidong, Li, Ning, Wu, Shuang, Zhou, Yizhuo, Shan, Yongli, Zhang, Qiangge, Ding, Chong, Yuan, Quan, Zhao, Fukun, Zeng, Rong, Zhu, Xueliang, 2008
- Human nudel and NudE as regulators of cytoplasmic dynein in poleward protein transport along the mitotic spindle, Yan, XM, Li, F, Liang, Y, Shen, YD, Zhao, XS, Huang, QP, Zhu, XL, 2003
Awards
- National Talent Program (2015): Eleventh Batch
- Shanghai Pujiang Talent Program (2014)
- CECAD/MPI-AGE Advanced Postdoctoral Fellowship (2013)
- Shanghai Natural Science Award, First Prize (2012)
- EMBO Long-Term Fellowship (2010)
- Chinese Academy of Sciences President's Award (2008)
