Professor | 沈义栋 | 数字化转型顾问

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Name	沈义栋
Contact Information	yidong.shen@sibcb.ac.cn
Language ability	中文, 英语, 德语
Province	上海

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Name

沈义栋

Contact Information

yidong.shen@sibcb.ac.cn

Language ability

中文, 英语, 德语

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2002-09 至 2008-01 博士: 中国科学院上海生命科学研究院 1998-09 至 2002-07 学士: 复旦大学
Work Experience	2014-05 至今 - 中国科学院上海生命科学研究院 - 研究员 2009-09 至 2014-04 - 德国马普衰老研究所 - 博士后 2009-04 至 2009-08 - 美国贝勒医学院 - 博士后 2008-02 至 2009-03 - 中国科学院上海生命科学研究院 - 助理研究员
Awards	国家级人才计划项目 (2015): 第十一批上海市浦江人才计划项目 (2014) CECAD/MPI-AGE高级博士后奖学金 (2013) 上海市自然科学奖, 一等奖 (2012) 欧洲分子生物组织(EMBO)长期奖学金 (2010) 中国科学院院长奖 (2008)

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2002-09 至 2008-01 博士: 中国科学院上海生命科学研究院
1998-09 至 2002-07 学士: 复旦大学

Work Experience

2014-05 至今 - 中国科学院上海生命科学研究院 - 研究员
2009-09 至 2014-04 - 德国马普衰老研究所 - 博士后
2009-04 至 2009-08 - 美国贝勒医学院 - 博士后
2008-02 至 2009-03 - 中国科学院上海生命科学研究院 - 助理研究员

Awards

国家级人才计划项目 (2015): 第十一批
上海市浦江人才计划项目 (2014)
CECAD/MPI-AGE高级博士后奖学金 (2013)
上海市自然科学奖, 一等奖 (2012)
欧洲分子生物组织(EMBO)长期奖学金 (2010)
中国科学院院长奖 (2008)

Areas of Focus	衰老及衰老相关疾病的机理研究
Publications	Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans, Xueqing Wang, Quanlong Jiang, Hongdao Zhang, Zhidong He, Yuanyuan Song, Yifan Chen, Na Tang, Yifei Zhou, Yiping Li, Adam Antebi, Ligang Wu, JingDong J Han, Yidong Shen, 2024 Ageing induces tissue-specific transcriptomic changes in Caenorhabditis elegans, Wang, Xueqing, Jiang, Quanlong, Song, Yuanyuan, He, Zhidong, Zhang, Hongdao, Song, Mengjiao, Zhang, Xiaona, Dai, Yumin, Karalay, Oezlem, Dieterich, Christoph, Antebi, Adam, Wu, Ligang, Han, JingDong J, Shen, Yidong, 2022 The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing, Yincong Zhang, Xiaona Zhang, Yumin Dai, Mengjiao Song, Yifei Zhou, Jun Zhou, Xiumin Yan, Yidong Shen, 2021 A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing, Yifei Zhou, Xueqing Wang, Mengjiao Song, Zhidong He, Guizhong Cui, Guangdun Peng, Christoph Dieterich, Adam Antebi, Naihe Jing, Yidong Shen, 2019 A microRNA switch controls dietary restriction-induced longevity through Wnt signaling, Xu, Yunpeng, He, Zhidong, Song, Mengjiao, Zhou, Yifei, Shen, Yidong, 2019 细胞“天线”——纤毛研究的前世今生, 张银聪, 鄢秀敏, 沈义栋, 2019 Dietary Restriction Induced Longevity Is Mediated by Nuclear Receptor NHR-62 in Caenorhabditis elegans, Heestand, Bree N, Shen, Yidong, Liu, Wei, Magner, Daniel B, Storm, Nadia, Meharg, Caroline, Habermann, Bianca, Antebi, Adam, 2013 The NHR-8 Nuclear Receptor Regulates Cholesterol and Bile Acid Homeostasis in C. elegans, Magner, Daniel B, Wollam, Joshua, Shen, Yidong, Hoppe, Caroline, Li, Dongling, Latza, Christian, Rottiers, Veerle, Hutter, Harald, Antebi, Adam, 2013 A Steroid Receptor-MicroRNA Switch Regulates Life Span in Response to Signals from the Gonad, Shen, Yidong, Wollam, Joshua, Magner, Daniel, Karalay, Oezlem, Antebi, Adam, 2012 A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity, Wollam, Joshua, Magner, Daniel B, Magomedova, Lilia, Rass, Elisabeth, Shen, Yidong, Rottiers, Veerle, Habermann, Bianca, Cummins, Carolyn L, Antebi, Adam, 2012 miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics, Cao, Jingli, Shen, Yidong, Zhu, Lei, Xu, Yanan, Zhou, Yizhuo, Wu, Zhili, Li, Yiping, Yan, Xiumin, Zhu, Xueliang, 2012 The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity, Wollam, Joshua, Magomedova, Lilia, Magner, Daniel B, Shen, Yidong, Rottiers, Veerle, Motola, Daniel L, Mangelsdorf, David J, Cummins, Carolyn L, Antebi, Adam, 2011 Live Show of Rho GTPases in Cell Migration, Yan, Xiumin, Shen, Yidong, Zhu, Xueliang, 2010 Nudel Promotes Axonal Lysosome Clearance and Endo-lysosome Formation via Dynein-Mediated Transport, Zhang, Qiangge, Wang, Fubin, Cao, Jingli, Shen, Yidong, Huang, Qiongping, Bao, Lan, Zhu, Xueliang

Areas of Focus

衰老及衰老相关疾病的机理研究

Publications

Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans, Xueqing Wang, Quanlong Jiang, Hongdao Zhang, Zhidong He, Yuanyuan Song, Yifan Chen, Na Tang, Yifei Zhou, Yiping Li, Adam Antebi, Ligang Wu, JingDong J Han, Yidong Shen, 2024
Ageing induces tissue-specific transcriptomic changes in Caenorhabditis elegans, Wang, Xueqing, Jiang, Quanlong, Song, Yuanyuan, He, Zhidong, Zhang, Hongdao, Song, Mengjiao, Zhang, Xiaona, Dai, Yumin, Karalay, Oezlem, Dieterich, Christoph, Antebi, Adam, Wu, Ligang, Han, JingDong J, Shen, Yidong, 2022
The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing, Yincong Zhang, Xiaona Zhang, Yumin Dai, Mengjiao Song, Yifei Zhou, Jun Zhou, Xiumin Yan, Yidong Shen, 2021
A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing, Yifei Zhou, Xueqing Wang, Mengjiao Song, Zhidong He, Guizhong Cui, Guangdun Peng, Christoph Dieterich, Adam Antebi, Naihe Jing, Yidong Shen, 2019
A microRNA switch controls dietary restriction-induced longevity through Wnt signaling, Xu, Yunpeng, He, Zhidong, Song, Mengjiao, Zhou, Yifei, Shen, Yidong, 2019
细胞“天线”——纤毛研究的前世今生, 张银聪, 鄢秀敏, 沈义栋, 2019
Dietary Restriction Induced Longevity Is Mediated by Nuclear Receptor NHR-62 in Caenorhabditis elegans, Heestand, Bree N, Shen, Yidong, Liu, Wei, Magner, Daniel B, Storm, Nadia, Meharg, Caroline, Habermann, Bianca, Antebi, Adam, 2013
The NHR-8 Nuclear Receptor Regulates Cholesterol and Bile Acid Homeostasis in C. elegans, Magner, Daniel B, Wollam, Joshua, Shen, Yidong, Hoppe, Caroline, Li, Dongling, Latza, Christian, Rottiers, Veerle, Hutter, Harald, Antebi, Adam, 2013
A Steroid Receptor-MicroRNA Switch Regulates Life Span in Response to Signals from the Gonad, Shen, Yidong, Wollam, Joshua, Magner, Daniel, Karalay, Oezlem, Antebi, Adam, 2012
A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity, Wollam, Joshua, Magner, Daniel B, Magomedova, Lilia, Rass, Elisabeth, Shen, Yidong, Rottiers, Veerle, Habermann, Bianca, Cummins, Carolyn L, Antebi, Adam, 2012
miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics, Cao, Jingli, Shen, Yidong, Zhu, Lei, Xu, Yanan, Zhou, Yizhuo, Wu, Zhili, Li, Yiping, Yan, Xiumin, Zhu, Xueliang, 2012
The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity, Wollam, Joshua, Magomedova, Lilia, Magner, Daniel B, Shen, Yidong, Rottiers, Veerle, Motola, Daniel L, Mangelsdorf, David J, Cummins, Carolyn L, Antebi, Adam, 2011
Live Show of Rho GTPases in Cell Migration, Yan, Xiumin, Shen, Yidong, Zhu, Xueliang, 2010
Nudel Promotes Axonal Lysosome Clearance and Endo-lysosome Formation via Dynein-Mediated Transport, Zhang, Qiangge, Wang, Fubin, Cao, Jingli, Shen, Yidong, Huang, Qiongping, Bao, Lan, Zhu, Xueliang

衰老衰老相关疾病癌症心血管疾病神经退行性疾病肥胖长寿通路限制饮食转录因子模式生物

俞章盛 - 上海交通大学

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