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沈义栋
Life Science
中国科学院大学
上海
Language: 中文, 英语, 德语
衰老
衰老相关疾病
癌症
心血管疾病
神经退行性疾病
肥胖
长寿通路
限制饮食
转录因子
模式生物
Areas of Focus
- 衰老及衰老相关疾病的机理研究
Work Experience
- 2014-05 至今 - 中国科学院上海生命科学研究院 - 研究员
- 2009-09 至 2014-04 - 德国马普衰老研究所 - 博士后
- 2009-04 至 2009-08 - 美国贝勒医学院 - 博士后
- 2008-02 至 2009-03 - 中国科学院上海生命科学研究院 - 助理研究员
Academic Background & Achievements
- 2002-09 至 2008-01 博士: 中国科学院上海生命科学研究院
- 1998-09 至 2002-07 学士: 复旦大学
Publications
- Tissue-specific profiling of age-dependent miRNAomic changes in Caenorhabditis elegans, Xueqing Wang, Quanlong Jiang, Hongdao Zhang, Zhidong He, Yuanyuan Song, Yifan Chen, Na Tang, Yifei Zhou, Yiping Li, Adam Antebi, Ligang Wu, JingDong J Han, Yidong Shen, 2024
- Ageing induces tissue-specific transcriptomic changes in Caenorhabditis elegans, Wang, Xueqing, Jiang, Quanlong, Song, Yuanyuan, He, Zhidong, Zhang, Hongdao, Song, Mengjiao, Zhang, Xiaona, Dai, Yumin, Karalay, Oezlem, Dieterich, Christoph, Antebi, Adam, Wu, Ligang, Han, JingDong J, Shen, Yidong, 2022
- The decrease of intraflagellar transport impairs sensory perception and metabolism in ageing, Yincong Zhang, Xiaona Zhang, Yumin Dai, Mengjiao Song, Yifei Zhou, Jun Zhou, Xiumin Yan, Yidong Shen, 2021
- A secreted microRNA disrupts autophagy in distinct tissues of Caenorhabditis elegans upon ageing, Yifei Zhou, Xueqing Wang, Mengjiao Song, Zhidong He, Guizhong Cui, Guangdun Peng, Christoph Dieterich, Adam Antebi, Naihe Jing, Yidong Shen, 2019
- A microRNA switch controls dietary restriction-induced longevity through Wnt signaling, Xu, Yunpeng, He, Zhidong, Song, Mengjiao, Zhou, Yifei, Shen, Yidong, 2019
- 细胞“天线”——纤毛研究的前世今生, 张银聪, 鄢秀敏, 沈义栋, 2019
- Dietary Restriction Induced Longevity Is Mediated by Nuclear Receptor NHR-62 in Caenorhabditis elegans, Heestand, Bree N, Shen, Yidong, Liu, Wei, Magner, Daniel B, Storm, Nadia, Meharg, Caroline, Habermann, Bianca, Antebi, Adam, 2013
- The NHR-8 Nuclear Receptor Regulates Cholesterol and Bile Acid Homeostasis in C. elegans, Magner, Daniel B, Wollam, Joshua, Shen, Yidong, Hoppe, Caroline, Li, Dongling, Latza, Christian, Rottiers, Veerle, Hutter, Harald, Antebi, Adam, 2013
- A Steroid Receptor-MicroRNA Switch Regulates Life Span in Response to Signals from the Gonad, Shen, Yidong, Wollam, Joshua, Magner, Daniel, Karalay, Oezlem, Antebi, Adam, 2012
- A Novel 3-Hydroxysteroid Dehydrogenase That Regulates Reproductive Development and Longevity, Wollam, Joshua, Magner, Daniel B, Magomedova, Lilia, Rass, Elisabeth, Shen, Yidong, Rottiers, Veerle, Habermann, Bianca, Cummins, Carolyn L, Antebi, Adam, 2012
- miR-129-3p controls cilia assembly by regulating CP110 and actin dynamics, Cao, Jingli, Shen, Yidong, Zhu, Lei, Xu, Yanan, Zhou, Yizhuo, Wu, Zhili, Li, Yiping, Yan, Xiumin, Zhu, Xueliang, 2012
- The Rieske oxygenase DAF-36 functions as a cholesterol 7-desaturase in steroidogenic pathways governing longevity, Wollam, Joshua, Magomedova, Lilia, Magner, Daniel B, Shen, Yidong, Rottiers, Veerle, Motola, Daniel L, Mangelsdorf, David J, Cummins, Carolyn L, Antebi, Adam, 2011
- Live Show of Rho GTPases in Cell Migration, Yan, Xiumin, Shen, Yidong, Zhu, Xueliang, 2010
- Nudel Promotes Axonal Lysosome Clearance and Endo-lysosome Formation via Dynein-Mediated Transport, Zhang, Qiangge, Wang, Fubin, Cao, Jingli, Shen, Yidong, Huang, Qiongping, Bao, Lan, Zhu, Xueliang
Awards
- 国家级人才计划项目 (2015): 第十一批
- 上海市浦江人才计划项目 (2014)
- CECAD/MPI-AGE高级博士后奖学金 (2013)
- 上海市自然科学奖, 一等奖 (2012)
- 欧洲分子生物组织(EMBO)长期奖学金 (2010)
- 中国科学院院长奖 (2008)
