Professor | Lei Tan | Asia Growth Partners

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Name	Lei Tan
Contact Information	lei.tan@siat.ac.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Lei Tan

Contact Information

lei.tan@siat.ac.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2002-09 to 2010-01 PhD: Peking University 1998-09 to 2002-07 Bachelor's: Peking University
Work Experience	2019-10 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher 2012-06 to 2019-06 - Weill Cornell Medical College, New York, USA - Postdoctoral Researcher 2010-11 to 2012-06 - Moffitt Cancer Center, Tampa, Florida, USA - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2002-09 to 2010-01 PhD: Peking University
1998-09 to 2002-07 Bachelor's: Peking University

Work Experience

2019-10 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
2012-06 to 2019-06 - Weill Cornell Medical College, New York, USA - Postdoctoral Researcher
2010-11 to 2012-06 - Moffitt Cancer Center, Tampa, Florida, USA - Postdoctoral Researcher

Areas of Focus	Synthetic Biology for Virus Vaccines Synthetic Biology for Stem Cells Polysaccharide Markers in Tumor Cells
Publications	Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors, Li, Hongda, SaucedoCuevas, Laura, Yuan, Ling, Ross, Danica, Johansen, Anide, Sands, Daniel, Stanley, Valentina, GuemezGamboa, Alicia, Gregor, Anne, Evans, Todd, Chen, Shuibing, Tan, Lei, Molina, Henrik, Sheets, Nicholas, Shiryaev, Sergey A, Terskikh, Alexey, V, Gladfelter, Amy S, Shresta, Sujan, Xu, Zhiheng, Gleeson, Joseph G., 2019 Pre- and peri-implantation Zika virus infection impairs fetal development by targeting trophectoderm cells, Lei Tan, Lauretta A Lacko, Ting Zhou, Delia Tomoiaga, Romulo Hurtado, Tuo Zhang, Ana Sevilla, Aaron Zhong, Christopher E Mason, Scott Noggle, Todd Evans, Heidi Stuhlmann, Robert E Schwartz, Shuibing Chen, 2019 Derivation and characterization of a UCP1 reporter human ES cell line, Mukherjee, Suranjit, Zhang, Tuo, Lacko, Lauretta A, Tan, Lei, Xiang, Jenny Zhaoying, Butler, Jason M, Chen, Shuibing, 2018 A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival, Ting Zhou, Tae Wan Kim, Chi Nok Chong, Lei Tan, Sadaf Amin, Zohreh Sadat Badieyan, Suranjit Mukherjee, Zaniar Ghazizadeh, Hui Zeng, Min Guo, Miguel Crespo, Tuo Zhang, Reyn Kenyon, Christopher L Robinson, Effie Apostolou, Hui Wang, Jenny Zhaoying Xiang, Todd Evans, Lorenz Studer, Shuibing Chen, 2018 High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain, Zhou, Ting, Tan, Lei, Cederquist, Gustav Y, Fan, Yujie, Hartley, Brigham J, Mukherjee, Suranjit, Tomishima, Mark, Brennand, Kristen J, Zhang, Qisheng, Schwartz, Robert E, Evans, Todd, Studer, Lorenz, Chen, Shuibing, 2017 An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery, Zeng, Hui, Guo, Min, Zhou, Ting, Tan, Lei, Chong, Chi Nok, Zhang, Tuo, Dong, Xue, Xiang, Jenny Zhaoying, Yu, Albert S, Yue, Lixia, Qi, Qibin, Evans, Todd, Graumann, Johannes, Chen, Shuibing, 2016 Holoclone Forming Cells from Pancreatic Cancer Cells Enrich Tumor Initiating Cells and Represent a Novel Model for Study of Cancer Stem Cells, Tan, Lei, Sui, Xin, Deng, Hongkui, Ding, Mingxiao, 2011 Analysis of ACE2 in polarized epithelial cells: surface expression and function as receptor for severe acute respiratory syndrome-associated coronavirus, Ren, Xiaofeng, Glende, Jorg, AlFalah, Marwan, de Vries, Victor, SchwegmannWessels, Christel, Qu, Xiuxia, Tan, Lei, Tschernig, Thomas, Deng, Hongkui, Naim, Hassan Y, Herrler, Georg, 2006 Nestin(neg)CD24(low/-) population from fetal Nestin-EGFP transgenic mice enriches the pancreatic endocrine progenitor cells, Wang, XJ, Hu, JJ, Zhao, DX, Wang, GW, Tan, L, Du, LY, Yang, J, Hou, LL, Zhang, H, Yu, YS, Zhang, H, Deng, HK, Ding, MX, 2005 Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression, Nie, YC, Wang, PG, Shi, XL, Wang, GW, Chen, J, Zheng, AH, Wang, W, Wang, Z, Qu, XX, Luo, M, Tan, L, Song, XJ, Yin, XL, Chen, JG, Ding, MX, Deng, HK, 2004 Expression cloning of functional receptor used by SARS coronavirus, Wang, PG, Chen, J, Zheng, AH, Nie, YC, Shi, XL, Wang, W, Wang, GW, Luo, M, Liu, HJ, Tan, L, Song, XJ, Wang, Z, Yin, XL, Qu, XX, Wang, XJ, Qing, TT, Ding, MX, Deng, HK, 2004

Areas of Focus

Synthetic Biology for Virus Vaccines
Synthetic Biology for Stem Cells
Polysaccharide Markers in Tumor Cells

Publications

Zika Virus Protease Cleavage of Host Protein Septin-2 Mediates Mitotic Defects in Neural Progenitors, Li, Hongda, SaucedoCuevas, Laura, Yuan, Ling, Ross, Danica, Johansen, Anide, Sands, Daniel, Stanley, Valentina, GuemezGamboa, Alicia, Gregor, Anne, Evans, Todd, Chen, Shuibing, Tan, Lei, Molina, Henrik, Sheets, Nicholas, Shiryaev, Sergey A, Terskikh, Alexey, V, Gladfelter, Amy S, Shresta, Sujan, Xu, Zhiheng, Gleeson, Joseph G., 2019
Pre- and peri-implantation Zika virus infection impairs fetal development by targeting trophectoderm cells, Lei Tan, Lauretta A Lacko, Ting Zhou, Delia Tomoiaga, Romulo Hurtado, Tuo Zhang, Ana Sevilla, Aaron Zhong, Christopher E Mason, Scott Noggle, Todd Evans, Heidi Stuhlmann, Robert E Schwartz, Shuibing Chen, 2019
Derivation and characterization of a UCP1 reporter human ES cell line, Mukherjee, Suranjit, Zhang, Tuo, Lacko, Lauretta A, Tan, Lei, Xiang, Jenny Zhaoying, Butler, Jason M, Chen, Shuibing, 2018
A hPSC-based platform to discover gene-environment interactions that impact human β-cell and dopamine neuron survival, Ting Zhou, Tae Wan Kim, Chi Nok Chong, Lei Tan, Sadaf Amin, Zohreh Sadat Badieyan, Suranjit Mukherjee, Zaniar Ghazizadeh, Hui Zeng, Min Guo, Miguel Crespo, Tuo Zhang, Reyn Kenyon, Christopher L Robinson, Effie Apostolou, Hui Wang, Jenny Zhaoying Xiang, Todd Evans, Lorenz Studer, Shuibing Chen, 2018
High-Content Screening in hPSC-Neural Progenitors Identifies Drug Candidates that Inhibit Zika Virus Infection in Fetal-like Organoids and Adult Brain, Zhou, Ting, Tan, Lei, Cederquist, Gustav Y, Fan, Yujie, Hartley, Brigham J, Mukherjee, Suranjit, Tomishima, Mark, Brennand, Kristen J, Zhang, Qisheng, Schwartz, Robert E, Evans, Todd, Studer, Lorenz, Chen, Shuibing, 2017
An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery, Zeng, Hui, Guo, Min, Zhou, Ting, Tan, Lei, Chong, Chi Nok, Zhang, Tuo, Dong, Xue, Xiang, Jenny Zhaoying, Yu, Albert S, Yue, Lixia, Qi, Qibin, Evans, Todd, Graumann, Johannes, Chen, Shuibing, 2016
Holoclone Forming Cells from Pancreatic Cancer Cells Enrich Tumor Initiating Cells and Represent a Novel Model for Study of Cancer Stem Cells, Tan, Lei, Sui, Xin, Deng, Hongkui, Ding, Mingxiao, 2011
Analysis of ACE2 in polarized epithelial cells: surface expression and function as receptor for severe acute respiratory syndrome-associated coronavirus, Ren, Xiaofeng, Glende, Jorg, AlFalah, Marwan, de Vries, Victor, SchwegmannWessels, Christel, Qu, Xiuxia, Tan, Lei, Tschernig, Thomas, Deng, Hongkui, Naim, Hassan Y, Herrler, Georg, 2006
Nestin(neg)CD24(low/-) population from fetal Nestin-EGFP transgenic mice enriches the pancreatic endocrine progenitor cells, Wang, XJ, Hu, JJ, Zhao, DX, Wang, GW, Tan, L, Du, LY, Yang, J, Hou, LL, Zhang, H, Yu, YS, Zhang, H, Deng, HK, Ding, MX, 2005
Highly infectious SARS-CoV pseudotyped virus reveals the cell tropism and its correlation with receptor expression, Nie, YC, Wang, PG, Shi, XL, Wang, GW, Chen, J, Zheng, AH, Wang, W, Wang, Z, Qu, XX, Luo, M, Tan, L, Song, XJ, Yin, XL, Chen, JG, Ding, MX, Deng, HK, 2004
Expression cloning of functional receptor used by SARS coronavirus, Wang, PG, Chen, J, Zheng, AH, Nie, YC, Shi, XL, Wang, W, Wang, GW, Luo, M, Liu, HJ, Tan, L, Song, XJ, Wang, Z, Yin, XL, Qu, XX, Wang, XJ, Qing, TT, Ding, MX, Deng, HK, 2004

Synthetic Biology Virus Vaccines Codon Expansion Stem Cells Polysaccharide Markers Tumor Cells Disease Models Tumor Therapy Cell Proliferation Differentiation Control

Jiangwei Lin - University of Chinese Academy of Sciences

Zhang He - Tongji University

He Zhang - Tongji University

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