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Wei Taotao
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
Mitochondria
Homeostasis
Cell Biology
Membrane
Structural Biology
Biophysics
Proteomics
Metabolic Diseases
Tumors
Nanobiomaterials
Areas of Focus
- Mitochondrial dynamics and homeostasis
- Membrane and cell biology
- Structural biology
- Single-molecule biophysics
- Proteomics and modification omics
- Metabolic diseases
- Malignant tumors
- Nanobiomaterials targeting mitochondria
- Energy metabolism regulation
- Tumor inhibition
Work Experience
- 2008-03 to Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
- 2001-02 to 2008-03 - Institute of Biophysics, Chinese Academy of Sciences - Associate Researcher
- 1999-07 to 2001-02 - Institute of Biophysics, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
- 1996-09 to 1999-06 Ph.D.: Institute of Biophysics, Chinese Academy of Sciences
- 1993-09 to 1996-07 Master's: Hubei Institute of Chemistry
- 1989-09 to 1993-06 Bachelor's: Huazhong University of Science and Technology
- Published over 60 SCI papers as corresponding and first author
- Total citations over 10,000, H-index 35
Publications
- Structural and biochemical insights into the mechanism of the Gabija bacterial immunity system, 11th Author, 2024
- Facing the Frontier of Science and Technology, Achieving Pioneering and Leading Progress of the Major Research Plan 'Organelle Interaction Network and Mechanisms', 4th Author, 2023
- Identification of lipid droplets in gut bacteria, 13th Author, 2023
- Mitochondrial elongation factor 4 modulates energy metabolism and promotes breast cancer metastasis by orchestration of mitochondrial translation, 11th Author, 2023
- 先贤虽去，风范永存——沉痛悼念杨福愉先生, 1st Author, 2023
- Phosphatidic acid: from biophysical properties to diverse functions, 11th Author, 2023
- Dynamic intracellular exchange of nanomaterials' protein corona perturbs proteostasis and remodels cell metabolism, 4th Author, 2022
- Metastable Iron Sulfides Gram-Dependently Counteract Resistant Gardnerella Vaginalis for Bacterial Vaginosis Treatment, 7th Author, 2022
- 中国细胞器互作研究的进展和趋势, 11th Author, 2022
- Chloroquine inhibits deferoxamine-induced ferritinophagy and potentiates the cytotoxicity of chemotherapy drugs in lung cancer cells., 11th Author, 2022
- Cardioprotective Role of SIRT5 in Response to Acute Ischemia Through a Novel Liver-Cardiac Crosstalk Mechanism, 11th Author, 2021
- Quantifying the phase separation property of chromatin-associated proteins under physiological conditions using an anti-1,6-hexanediol index, 8th Author, 2021
- Aberrantly Upregulated EF4 Is Crucial for The Proliferation and Migration of Bladder Urothelial Carcinoma Cells via Orchestration of Mitochondrial Oxidative Phosphorylation, 11th Author, 2021
- PEG-GO@XN nanocomposite suppresses breast cancer metastasis via inhibition of mitochondrial oxidative phosphorylation and blockade of epithelial-to-mesenchymal transition, 11th Author, 2021
- Airway relaxation mechanisms and structural basis of osthole to improve lung function in asthma, 11th Author, 2020
- Coniferaldehyde attenuates Alzheimer's pathology via activation of Nrf2 and its targets, 10th Author, 2020
- KAP1-associated transcriptional inhibitory complex regulates C2C12 myoblasts differentiation and mitochondrial biogenesis via miR-133a repression, 11th Author, 2020
- Identification of Malonylation, Succinylation, and Glutarylation in Serum Proteins of Acute Myocardial Infarction Patients, 11th Author, 2020
- Genetically Encoded FapR-NLuc as a Biosensor to Determine Malonyl-CoA in Situ at Subcellular Scales, 11th Author, 2019
- Detection of tBid Oligomerization and Membrane Permeabilization by Graphene-Based Single-Molecule Surface-Induced Fluorescence Attenuation, 11th Author, 2019
- Targeting the functional interplay between endoplasmic reticulum oxidoreductin-1 alpha and protein disulfide isomerase suppresses the progression of cervical cancer, 12th Author, 2019
- YWHA/14-3-3 proteins recognize phosphorylated TFEB by a noncanonical mode for controlling TFEB cytoplasmic localization, 11th Author, 2019
- Transforming growth factor (TGF)-beta1-induced miR-133a inhibits myofibroblast differentiation and pulmonary fibrosis, 11th Author, 2019
- Suppression of Tumor Energy Supply by Liposomal Nanoparticle-Mediated Inhibition of Aerobic Glycolysis., 13th Author, 2018
- Tissue distribution, subcellular localization, and enzymatic activity analysis of human SIRT5 isoforms, 11th Author, 2018
- Highly Fluorescent Chiral N-S-Doped Carbon Dots from Cysteine Affect Cellular Energy Metabolism, 6th Author, 2018
- SIRT5 deacylates metabolism-related proteins and attenuates hepatic steatosis in ob/ob mice, 11th Author, 2018
- Human Elongation Factor 4 Regulates Cancer Bioenergetics by Acting as a Mitochondrial Translation Switch, 11th Author, 2018
- ESeroS-GS Protects Neuronal Cells from Oxidative Stress by Stabilizing Lysosomes, 11th Author, 2016
- Interactions of graphene with mammalian cells: Molecular mechanisms and biomedical insights, 11th Author, 2016
- Phorbol myristate acetate suppresses breast cancer cell growth via down-regulation of P-Rex1 expression, 11th Author, 2016
- Prediction of Protein Lysine Acylation by Integrating Primary Sequence Information with Multiple Functional Features, 11th Author, 2016
- Aberrantly upregulated TRAP1 is required for tumorigenesis of breast cancer, 11th Author, 2015
- Oxidovanadium(IV) sulfate-induced glucose uptake in HepG2 cells through IR/Akt pathway and hydroxyl radicals, 4th Author, 2015
Awards
- Beijing Higher Education Quality Undergraduate Teaching Material Key Project (2023): Provincial
- Li Pei Excellent Teacher Award, University of Chinese Academy of Sciences (2023): Institute
- Beijing Course Ideological and Political Teaching Master (2022): Provincial
- Yanyan Silver Award - Zhenchi Award, University of Chinese Academy of Sciences (2022): Institute
- Beijing Course Ideological and Political Demonstration Course (2022): Provincial
- Excellent Graduate Course, University of Chinese Academy of Sciences (2022): Institute
- Course Ideological and Political Demonstration Course, University of Chinese Academy of Sciences (2021): Institute
- Yanyan Gold Award - Navigation Award, University of Chinese Academy of Sciences (2021): Institute
- National First-Class Undergraduate Course (2020): National
- Jiangxi Provincial Natural Science Award, Second Prize (2020): Provincial
- Excellent Undergraduate Course, University of Chinese Academy of Sciences (2020): Institute
- Boutique Course, School of Life Sciences, University of Chinese Academy of Sciences (2019): Institute
