Professor | Ji-Qin Wu | Asia Growth Partners

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Name	Ji-Qin Wu
Contact Information	wujiqin@wh.iov.cn
Language ability	Chinese, English
Province	Hubei

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Name

Ji-Qin Wu

Contact Information

wujiqin@wh.iov.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2012-09--2017-07 PhD: Wuhan Institute of Virology, Chinese Academy of Sciences 2008-09--2012-06 Bachelor's Degree: Ocean University of China
Work Experience	2022-10~Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Young Researcher 2021-10~2022-10 - Wuhan Institute of Virology, Chinese Academy of Sciences - Associate Researcher 2020-04~2021-10 - Wuhan Institute of Virology, Chinese Academy of Sciences - Assistant Researcher 2018-05~2020-04 - Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences - Postdoctoral Researcher 2017-07~2018-05 - Wuhan Institute of Virology, Chinese Academy of Sciences - Experimentalist

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2012-09--2017-07 PhD: Wuhan Institute of Virology, Chinese Academy of Sciences
2008-09--2012-06 Bachelor's Degree: Ocean University of China

Work Experience

2022-10~Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Young Researcher
2021-10~2022-10 - Wuhan Institute of Virology, Chinese Academy of Sciences - Associate Researcher
2020-04~2021-10 - Wuhan Institute of Virology, Chinese Academy of Sciences - Assistant Researcher
2018-05~2020-04 - Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences - Postdoctoral Researcher
2017-07~2018-05 - Wuhan Institute of Virology, Chinese Academy of Sciences - Experimentalist

Areas of Focus	RNA virus genome replication mechanisms Nucleic acid and nucleoside drug intervention mechanisms
Publications	A jingmenvirus RNA-dependent RNA polymerase structurally resembles the flavivirus counterpart but with different features at the initiation phase, Ji-Qin Wu, 2024 LGP2 directly interacts with flavivirus NS5 RNA-dependent RNA polymerase and downregulates its pre-elongation activities, Ji-Qin Wu, 2023 Crystal structure of African swine fever virus pE301R reveals a ring-shaped trimeric DNA sliding clamp, Ji-Qin Wu, 2023 RNA-Dependent RNA Polymerase of the Second Human Pegivirus Exhibits a High-Fidelity Feature, Ji-Qin Wu, 2022 Assessment of nucleotide/nucleoside analog intervention in primer-dependent viral RNA-dependent RNA polymerases, Ji-Qin Wu, 2022 Structural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases, Ji-Qin Wu, 2022 Remdesivir overcomes the S861 roadblock in SARS-CoV-2 polymerase elongation complex, Ji-Qin Wu, 2021 Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase, Ji-Qin Wu, 2020 A conformation-based intra-molecular initiation factor identified in the flavivirus RNA-dependent RNA polymerase, Ji-Qin Wu, 2020 Visualizing the nucleotide addition cycle of viral rna-dependent rna polymerase, Ji-Qin Wu, 2018 A Structural Overview of RNA-Dependent RNA Polymerases from the Flaviviridae Family, Ji-Qin Wu, 2015 Perturbation in the Conserved Methyltransferase-Polymerase Interface of Flavivirus NS5 Differentially Affects Polymerase Initiation and Elongation, Ji-Qin Wu, 2015

Areas of Focus

RNA virus genome replication mechanisms
Nucleic acid and nucleoside drug intervention mechanisms

Publications

A jingmenvirus RNA-dependent RNA polymerase structurally resembles the flavivirus counterpart but with different features at the initiation phase, Ji-Qin Wu, 2024
LGP2 directly interacts with flavivirus NS5 RNA-dependent RNA polymerase and downregulates its pre-elongation activities, Ji-Qin Wu, 2023
Crystal structure of African swine fever virus pE301R reveals a ring-shaped trimeric DNA sliding clamp, Ji-Qin Wu, 2023
RNA-Dependent RNA Polymerase of the Second Human Pegivirus Exhibits a High-Fidelity Feature, Ji-Qin Wu, 2022
Assessment of nucleotide/nucleoside analog intervention in primer-dependent viral RNA-dependent RNA polymerases, Ji-Qin Wu, 2022
Structural basis of transition from initiation to elongation in de novo viral RNA-dependent RNA polymerases, Ji-Qin Wu, 2022
Remdesivir overcomes the S861 roadblock in SARS-CoV-2 polymerase elongation complex, Ji-Qin Wu, 2021
Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase, Ji-Qin Wu, 2020
A conformation-based intra-molecular initiation factor identified in the flavivirus RNA-dependent RNA polymerase, Ji-Qin Wu, 2020
Visualizing the nucleotide addition cycle of viral rna-dependent rna polymerase, Ji-Qin Wu, 2018
A Structural Overview of RNA-Dependent RNA Polymerases from the Flaviviridae Family, Ji-Qin Wu, 2015
Perturbation in the Conserved Methyltransferase-Polymerase Interface of Flavivirus NS5 Differentially Affects Polymerase Initiation and Elongation, Ji-Qin Wu, 2015

Rna Virus Genome Replication Mechanisms Nucleic Acid Nucleoside Drug Intervention Virology Molecular Biology Biochemistry Viral Replication

Yanfang Wang - Tongji University

Shaojun Dai - Shanghai Normal University

Shui Wang - Shanghai Normal University

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