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Yu Chuan Wang
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
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Metalloproteins Synthetic Biology Catalytic Activity Selenoproteins Biochemical Function Omics Drug Mechanism Proteomics Metabolomics Antimicrobial
Areas of Focus
  • Synthetic Biology Modification and Catalytic Activity Expansion of Metalloproteins
  • Expression and Biochemical Function of Selenoproteins
  • Mechanism of Drug Action Based on Omics Methods
Work Experience
  • 2019-06 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
  • 2019-01 to 2019-05 - University of Hong Kong - Postdoctoral Researcher
  • 2015-12 to 2018-12 - Sun Yat-sen University - Associate Researcher
Academic Background & Achievements
  • 2010-09 to 2015-12 PhD: University of Hong Kong
  • 2008-09 to 2010-07 Master's: Sun Yat-sen University
  • 2004-09 to 2008-07 Bachelor's: Sun Yat-sen University
Publications
  • Metalloproteomics for Unveiling the Mechanism of Action of Metallodrugs, Yu Chuan Wang, 2019
  • Combination of gallium(III) with acetate for combating antibiotic resistant Pseudomonas aeruginosa, Yu Chuan Wang, 2019
  • Deciphering molecular mechanism of silver by integrated omic approaches enables enhancing its antimicrobial efficacy in E. coli, Yu Chuan Wang, 2019
  • Predicting disease-associated mutation of metal-binding sites in proteins using a deep learning approach, Yu Chuan Wang, 2019
  • Multi-omics and temporal dynamics profiling reveal disruption of central metabolism in Helicobacter pylori on bismuth treatment, Yu Chuan Wang, 2018
  • Integrative approach for the analysis of the proteome-wide response to bismuth drugs in Helicobacter pylori, Yu Chuan Wang, 2017
  • Metallomic and metalloproteomic strategies in elucidating the molecular mechanisms of metallodrugs, Yu Chuan Wang, 2015
  • Bio-coordination of bismuth in Helicobacter pylori revealed by immobilized metal affinity chromatography, Yu Chuan Wang, 2015
  • On-line coupling of continuous-flow gel electrophoresis with inductively coupled plasma-mass spectrometry to quantitatively evaluate intracellular metal binding properties of metallochaperones HpHypA and HpHspA in E. coli cells, Yu Chuan Wang, 2015
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