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Guangchuan Wang
Life Science
University of Chinese Academy of Sciences
Shanghai
Language: Chinese, English
Cancer
Immune System
Therapy
Microenvironment
Tumor
Immunology
Research
Biology
Genetics
Crispr
Areas of Focus
- Tumor Immunology
- Immunotherapy
- Tumor Microenvironment
Work Experience
- 2021-01~Present - Chinese Academy of Sciences, Center for Excellence in Molecular Cell Science - Researcher
- 2016-05~2021-01 - Yale University School of Medicine - Postdoctoral & Associate Researcher
- 2013-09~2016-05 - Zhejiang University - Lecturer
Academic Background & Achievements
- 2007-09--2013-06 PhD: Zhejiang University
- 2003-09--2007-06 Bachelor: Zhejiang University of Technology
Publications
- CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade, Guangchuan Wang, 2020
- Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity InVivo, Guangchuan Wang, 2019
- In vivo profiling of metastatic double knockouts through CRISPR-Cpf1 screens, Guangchuan Wang, 2019
- Systematic identification of immunotherapy targets using genome-scale in vivo CRISPR screens in CD8+ cytotoxic T cells., Guangchuan Wang, 2019
- Multiplexed activation of endogenous genes by CRISPRa elicits potent anti-tumor immunity, Guangchuan Wang, 2019
- Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening, Guangchuan Wang, 2018
- AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma (vol 20, pg 1329, 2017), Guangchuan Wang, 2017
- Robust vaccine formulation produced by assembling a hybrid coating of polyethyleneimine-silica, Guangchuan Wang, 2016
- Hydrated Silica Exterior Produced by Biomimetic Silicification Confers Viral Vaccine Heat-Resistance, Guangchuan Wang, 2015
- Rational design of thermostable vaccines by engineered peptide-induced virus self-biomineralization under physiological conditions, Guangchuan Wang, 2013
- Eggshell-Inspired Biomineralization Generates Vaccines that Do Not Require Refrigeration, Guangchuan Wang, 2012
- Extracellular Silica Nanocoat Confers Thermotolerance on Individual Cells: A Case Study of Material-Based Functionalization of Living Cells, Guangchuan Wang, 2010
Awards
- CRI-Irvington Postdoctoral Fellowship (2017): Research Institute
