Professor | 王广川 | 数字化转型顾问

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Name	王广川
Contact Information	guangchuan.wang@sibcb.ac.cn
Language ability	中文, 英语
Province	上海

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Name

王广川

Contact Information

guangchuan.wang@sibcb.ac.cn

Language ability

中文, 英语

Province

上海

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2007-09--2013-06 博士: 浙江大学 2003-09--2007-06 学士: 浙江工业大学
Work Experience	2021-01~现在 - 中科院分子细胞科学卓越创新中心 - 研究员 2016-05~2021-01 - 耶鲁大学医学院 - 博士后&副研究员 2013-09~2016-05 - 浙江大学 - 讲师
Awards	CRI-Irvington博士后奖学金 (2017): 研究所

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2007-09--2013-06 博士: 浙江大学
2003-09--2007-06 学士: 浙江工业大学

Work Experience

2021-01~现在 - 中科院分子细胞科学卓越创新中心 - 研究员
2016-05~2021-01 - 耶鲁大学医学院 - 博士后&副研究员
2013-09~2016-05 - 浙江大学 - 讲师

Awards

CRI-Irvington博士后奖学金 (2017): 研究所

Areas of Focus	肿瘤免疫学免疫治疗肿瘤微环境
Publications	CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade, 王广川, 2020 Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity InVivo, 王广川, 2019 In vivo profiling of metastatic double knockouts through CRISPR-Cpf1 screens, 王广川, 2019 Systematic identification of immunotherapy targets using genome-scale in vivo CRISPR screens in CD8+ cytotoxic T cells., 王广川, 2019 Multiplexed activation of endogenous genes by CRISPRa elicits potent anti-tumor immunity, 王广川, 2019 Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening, 王广川, 2018 AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma (vol 20, pg 1329, 2017), 王广川, 2017 Robust vaccine formulation produced by assembling a hybrid coating of polyethyleneimine-silica, 王广川, 2016 Hydrated Silica Exterior Produced by Biomimetic Silicification Confers Viral Vaccine Heat-Resistance, 王广川, 2015 Rational design of thermostable vaccines by engineered peptide-induced virus self-biomineralization under physiological conditions, 王广川, 2013 Eggshell-Inspired Biomineralization Generates Vaccines that Do Not Require Refrigeration, 王广川, 2012 Extracellular Silica Nanocoat Confers Thermotolerance on Individual Cells: A Case Study of Material-Based Functionalization of Living Cells, 王广川, 2010

Areas of Focus

肿瘤免疫学
免疫治疗
肿瘤微环境

Publications

CRISPR-GEMM Pooled Mutagenic Screening Identifies KMT2D as a Major Modulator of Immune Checkpoint Blockade, 王广川, 2020
Convergent Identification and Interrogation of Tumor-Intrinsic Factors that Modulate Cancer Immunity InVivo, 王广川, 2019
In vivo profiling of metastatic double knockouts through CRISPR-Cpf1 screens, 王广川, 2019
Systematic identification of immunotherapy targets using genome-scale in vivo CRISPR screens in CD8+ cytotoxic T cells., 王广川, 2019
Multiplexed activation of endogenous genes by CRISPRa elicits potent anti-tumor immunity, 王广川, 2019
Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening, 王广川, 2018
AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma (vol 20, pg 1329, 2017), 王广川, 2017
Robust vaccine formulation produced by assembling a hybrid coating of polyethyleneimine-silica, 王广川, 2016
Hydrated Silica Exterior Produced by Biomimetic Silicification Confers Viral Vaccine Heat-Resistance, 王广川, 2015
Rational design of thermostable vaccines by engineered peptide-induced virus self-biomineralization under physiological conditions, 王广川, 2013
Eggshell-Inspired Biomineralization Generates Vaccines that Do Not Require Refrigeration, 王广川, 2012
Extracellular Silica Nanocoat Confers Thermotolerance on Individual Cells: A Case Study of Material-Based Functionalization of Living Cells, 王广川, 2010

癌症免疫系统治疗微环境肿瘤免疫学研究生物学遗传学 Crispr

康九红 - 同济大学

王海芸 - 同济大学

Area of Focus
肿瘤 | 异质性 | 精准 | 用药 | 联合 | 癌症 | 生物标志物 | 新型 | 研究 | 分子

曹志伟 - 同济大学

Area of Focus
协同 | 药物 | 计算 | 多成分 | 中医 | 癌症 | 治疗 | 生物信息学 | 网络分析 | 数据库

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