Professor | Lin Wang | Asia Growth Partners

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Name	Lin Wang
Contact Information	wanglin2015@mail.kiz.ac.cn
Language ability	Chinese, English
Province	Yunnan

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Name

Lin Wang

Contact Information

wanglin2015@mail.kiz.ac.cn

Language ability

Chinese, English

Province

Yunnan

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2006-09--2011-07 PhD: Peking Union Medical College 2001-09--2005-07 Bachelor's: Yunnan University
Work Experience	2022-01~Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher 2015-09~2021-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher 2011-09~2015-09 - Tsinghua University - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2006-09--2011-07 PhD: Peking Union Medical College
2001-09--2005-07 Bachelor's: Yunnan University

Work Experience

2022-01~Present - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
2015-09~2021-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher
2011-09~2015-09 - Tsinghua University - Postdoctoral Researcher

Areas of Focus	Pluripotent Stem Cell Genomic Stability
Publications	Characterization of long-term ex vivo expansion of tree shrew spermatogonial stem cells., ZOOLOGICAL RESEARCH, 2023 Long noncoding RNA Lnc530 localizes on R-loops and regulates R-loop formation and genomic stability in mouse embryonic stem cells, STEM CELL REPORTS, 2023 Lnc956 -TRIM28-HSP90B1 complex on replication forks promotes CMG helicase retention to ensure stem cell genomic stability and embryogenesis, SCIENCE ADVANCES, 2023 DPPA5A suppresses the mutagenic TLS and MMEJ pathways by modulating the cryptic splicing of Rev1 and Polq in mouse embryonic stem cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023 Lnc956 regulates mouse embryonic stem cell differentiation in response to DNA damage in a p53-independent pathway, SCIENCE ADVANCES, 2023 Efficient endothelial and smooth muscle cell differentiation from human pluripotent stem cells through a simplified insulin-free culture system, BIOMATERIALS, 2021 A novel lncRNA Discn fine-tunes replication protein A (RPA) availability to promote genomic stability, NATURE COMMUNICATIONS, 2021 Homozygous MESP1 knock-in reporter hESCs facilitated cardiovascular cell differentiation and myocardial infarction repair, THERANOSTICS, 2020 Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia, SCIENCE ADVANCES, 2020 In vitro culture of cynomolgus monkey embryos beyond early gastrulation, SCIENCE, 2019 Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells, SCIENCE ADVANCES, 2019 Maternal gene Ooep may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes, ZOOLOGICAL RESEARCH, 2018 Biphasic modulation of insulin signaling enables highly efficient hematopoietic differentiation from human pluripotent stem cells, STEM CELL RESEARCH & THERAPY, 2018 Dgcr8 deletion in the primitive heart uncovered novel microRNA regulating the balance of cardiac-vascular gene program, PROTEIN & CELL, 2018 Maternal gene Ooep may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes, 动物学研究, 2018 Long-term propagation of tree shrew spermatogonial stem cells in culture and successful generation of transgenic offspring, CELL RESEARCH, 2017 Optimizing mesoderm progenitor selection and three-dimensional microniche culture allows highly efficient endothelial differentiation and ischemic tissue repair from human pluripotent stem cells, STEM CELL RESEARCH & THERAPY, 2017 Adenovirus-mediated overexpression of cardiac troponin I-interacting kinase promotes cardiomyocyte hypertrophy, CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2011

Areas of Focus

Pluripotent Stem Cell Genomic Stability

Publications

Characterization of long-term ex vivo expansion of tree shrew spermatogonial stem cells., ZOOLOGICAL RESEARCH, 2023
Long noncoding RNA Lnc530 localizes on R-loops and regulates R-loop formation and genomic stability in mouse embryonic stem cells, STEM CELL REPORTS, 2023
Lnc956 -TRIM28-HSP90B1 complex on replication forks promotes CMG helicase retention to ensure stem cell genomic stability and embryogenesis, SCIENCE ADVANCES, 2023
DPPA5A suppresses the mutagenic TLS and MMEJ pathways by modulating the cryptic splicing of Rev1 and Polq in mouse embryonic stem cells, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023
Lnc956 regulates mouse embryonic stem cell differentiation in response to DNA damage in a p53-independent pathway, SCIENCE ADVANCES, 2023
Efficient endothelial and smooth muscle cell differentiation from human pluripotent stem cells through a simplified insulin-free culture system, BIOMATERIALS, 2021
A novel lncRNA Discn fine-tunes replication protein A (RPA) availability to promote genomic stability, NATURE COMMUNICATIONS, 2021
Homozygous MESP1 knock-in reporter hESCs facilitated cardiovascular cell differentiation and myocardial infarction repair, THERANOSTICS, 2020
Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia, SCIENCE ADVANCES, 2020
In vitro culture of cynomolgus monkey embryos beyond early gastrulation, SCIENCE, 2019
Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells, SCIENCE ADVANCES, 2019
Maternal gene Ooep may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes, ZOOLOGICAL RESEARCH, 2018
Biphasic modulation of insulin signaling enables highly efficient hematopoietic differentiation from human pluripotent stem cells, STEM CELL RESEARCH & THERAPY, 2018
Dgcr8 deletion in the primitive heart uncovered novel microRNA regulating the balance of cardiac-vascular gene program, PROTEIN & CELL, 2018
Maternal gene Ooep may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes, 动物学研究, 2018
Long-term propagation of tree shrew spermatogonial stem cells in culture and successful generation of transgenic offspring, CELL RESEARCH, 2017
Optimizing mesoderm progenitor selection and three-dimensional microniche culture allows highly efficient endothelial differentiation and ischemic tissue repair from human pluripotent stem cells, STEM CELL RESEARCH & THERAPY, 2017
Adenovirus-mediated overexpression of cardiac troponin I-interacting kinase promotes cardiomyocyte hypertrophy, CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2011

Pluripotent Stem Cell Genomic Stability Dna Damage Repair Embryogenesis Differentiation R-Loops Replication

Shilong Wang - Tongji University

Wenwen Jia - Tongji University

Li Baojie - Shanghai Jiao Tong University

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