2008-09 to 2012-07 Bachelor's Degree: Wuhan University
2022-11 to Present - Chinese Academy of Sciences Wuhan Institute of Virology - Researcher
2018-08 to 2022-11 - Yale University - Postdoctoral Researcher
2018-03 to 2018-08 - UT Health - Postdoctoral Researcher
Postdoctoral Scholar Registration Award (2021): American Society for Virology
Postdoctoral Scholar Travel Award (2020): American Society for Virology
Rudolph J. Anderson Postdoctoral Fellowship (2019): Yale University
Academic Innovation Award (2019): Wuhan University, Second Prize
Academic Innovation Award (2018): Wuhan University, First Prize
Research
Molecular mechanisms of virus-host interactions Development of host-based antiviral therapies
Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection., Wei, Jin, Patil, Ajinkya, Collings, Clayton K, Alfajaro, Mia Madel, Liang, Yu, Cai, Wesley L, Strine, Madison S, Filler, Renata B, DeWeirdt, Peter C, Hanna, Ruth E, Menasche, Bridget L, Okten, Arya, PenaHernandez, Mario A, Klein, Jon, McNamara, Andrew, Rosales, Romel, McGovern, Briana L, Rodriguez, M Luis, GarciaSastre, Adolfo, White, Kris M, Qin, Yiren, Doench, John G, Yan, Qin, Iwasaki, Akiko, Zwaka, Thomas P, Qi, Jun, Kadoch, Cigall, Wilen, Craig B., 2023
The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression., Jin Wei, Mia Madel Alfajaro, Wesley L Cai, Vincent R Graziano, Madison S Strine, Renata B Filler, Scott B Biering, Sylvia A Sarnik, Sonam Patel, Bridget L Menasche, Susan R Compton, Silvana Konermann, Patrick D Hsu, Robert C Orchard, Qin Yan, Craig B Wilen, Jacob S Yount., 2023
DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner., Madison S. Strine, Wesley L. Cai, Jin Wei, Mia Madel Alfajaro, Renata B. Filler, Scott B. Biering, Sylvia Sarnik, Ryan D. Chow, Ajinkya Patil, Kasey S. Cervantes, Clayton K. Collings, Peter C. DeWeirdt, Ruth E. Hanna, Kevin Schofield, Christopher Hulme, Silvana Konermann, John G. Doench, Patrick D. Hsu, Cigall Kadoch, Qin Yan, Craig B. Wilen., 2023
Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer., Fernando J de Miguel, Claudia Gentile, William W Feng, Shannon J Silva, Akshay Sankar, Francisco Exposito, Wesley L Cai, Mary Ann Melnick, Camila RoblesOteiza, Madeline M Hinkley, Jeanelle A Tsai, AntjaVoy Hartley, Jin Wei, Anna Wurtz, Fangyong Li, Maria I Toki, David L Rimm, Robert Homer, Craig B Wilen, Andrew Z Xiao, Jun Qi, Qin Yan, Don X Nguyen, Pasi A Jnne, Cigall Kadoch, Katerina A Politi., 2023
High-affinity, neutralizing antibodies to SARS-CoV-2 can be made without T follicular helper cells., Chen, Jennifer S, Chow, Ryan D, Song, Eric, Mao, Tianyang, Israelow, Benjamin, Kamath, Kathy, Bozekowski, Joel, Haynes, Winston A, Filler, Renata B, Menasche, Bridget L, Wei, Jin, Alfajaro, Mia Madel, Song, Wenzhi, Peng, Lei, Carter, Lauren, Weinstein, Jason S, Gowthaman, Uthaman, Chen, Sidi, Craft, Joe, Shon, John C, Iwasaki, Akiko, Wilen, Craig B, Eisenbarth, Stephanie C., 2022
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection., Biering, Scott B, Sarnik, Sylvia A, Wang, Eleanor, Zengel, James R, Leist, Sarah R, Schafer, Alexandra, Sathyan, Varun, Hawkins, Padraig, Okuda, Kenichi, Tau, Cyrus, Jangid, Aditya R, Duffy, Connor, V, Wei, Jin, Gilmore, Rodney C, Alfajaro, Mia Madel, Strine, Madison S, Nguyenla, Xammy, Van Dis, Erik, Catamura, Carmelle, Yamashiro, Livia H, Belk, Julia A, Begeman, Adam, Stark, Jessica C, Shon, D Judy, Fox, Douglas M, Ezzatpour, Shahrzad, Huang, Emily, Olegario, Nico, Rustagi, Arjun, Volmer, Allison S, LivraghiButrico, Alessandra, Wehri, Eddie, Behringer, Richard R, Cheon, DongJoo, Schaletzky, Julia, Aguilar, Hector C, Puschnik, Andreas S, Button, Brian, Pinsky, Benjamin A, Blish, Catherine A, Baric, Ralph S, ONeal, Wanda K, Bertozzi, Carolyn R, Wilen, Craig B, Boucher, Richard C, Carette, Jan E, Stanley, Sarah A, Harris, Eva, Konermann, Silvana, Hsu, Patrick D., 2022
Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617., Peng, Lei, Hu, Yingxia, Mankowski, Madeleine C, Ren, Ping, Chen, Rita E, Wei, Jin, Zhao, Min, Li, Tongqing, Tripler, Therese, Ye, Lupeng, Chow, Ryan D, Fang, Zhenhao, Wu, Chunxiang, Dong, Matthew B, Cook, Matthew, Wang, Guilin, Clark, Paul, Nelson, Bryce, Klein, Daryl, Sutton, Richard, Diamond, Michael S, Wilen, Craig B, Xiong, Yong, Chen, Sidi., 2022
Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection., Wei, Jin, Alfajaro, Mia Madel, DeWeirdt, Peter C, Hanna, Ruth E, LuCulligan, William J, Cai, Wesley L, Strine, Madison S, Zhang, ShangMin, Graziano, Vincent R, Schmitz, Cameron O, Chen, Jennifer S, Mankowski, Madeleine C, Filler, Renata B, Ravindra, Neal G, Gasque, Victor, de Miguel, Fernando J, Patil, Ajinkya, Chen, Huacui, Oguntuyo, Kasopefoluwa Y, Abriola, Laura, Surovtseva, Yulia, V, Orchard, Robert C, Lee, Benhur, Lindenbach, Brett D, Politi, Katerina, van Dijk, David, Kadoch, Cigall, Simon, Matthew D, Yan, Qin, Doench, John G, Wilen, Craig B., 2021
Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium identifies target cells, alterations in gene expression, and cell state changes., Ravindra, Neal G, Alfajaro, Mia Madel, Gasque, Victor, Huston, Nicholas C, Wan, Han, SzigetiBuck, Klara, Yasumoto, Yuki, Greaney, Allison M, Habet, Victoria, Chow, Ryan D, Chen, Jennifer S, Wei, Jin, Filler, Renata B, Wang, Bao, Wang, Guilin, Niklason, Laura E, Montgomery, Ruth R, Eisenbarth, Stephanie C, Chen, Sidi, Williams, Adam, Iwasaki, Akiko, Horvath, Tamas L, Foxman, Ellen F, Pierce, Richard W, Pyle, Anna Marie, van Dijk, David, Wilen, Craig B., 2021
CD300lf Conditional Knockout Mouse Reveals Strain-Specific Cellular Tropism of Murine Norovirus., Graziano, Vincent R, Alfajaro, Mia Madel, Schmitz, Cameron O, Filler, Renata B, Strine, Madison S, Wei, Jin, Hsieh, Leon L, Baldridge, Megan T, Nice, Timothy J, Lee, Sanghyun, Orchard, Robert C, Wilen, Craig B., 2021
Nonsteroidal Anti-inflammatory Drugs Dampen the Cytokine and Antibody Response to SARS-CoV-2 Infection., Chen, Jennifer S, Alfajaro, Mia Madel, Chow, Ryan D, Wei, Jin, Filler, Renata B, Eisenbarth, Stephanie C, Wilen, Craig B., 2021
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions., Flynn, Ryan A, Belk, Julia A, Qi, Yanyan, Yasumoto, Yuki, Wei, Jin, Alfajaro, Mia Madel, Shi, Quanming, Mumbach, Maxwell R, Limaye, Aditi, DeWeirdt, Peter C, Schmitz, Cameron O, Parker, Kevin R, Woo, Elizabeth, Chang, Howard Y, Horvath, Tamas L, Carette, Jan E, Bertozzi, Carolyn R, Wilen, Craig B, Satpathy, Ansuman T., 2021
CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus., Graziano, Vincent R, Walker, Forrest C, Kennedy, Elizabeth A, Wei, Jin, Ettayebi, Khalil, Strine, Madison S, Filler, Renata B, Hassan, Ebrahim, Hsieh, Leon L, Kim, Arthur S, Kolawole, Abimbola O, Wobus, Christiane E, Lindesmith, Lisa C, Baric, Ralph S, Estes, Mary K, Orchard, Robert C, Baldridge, Megan T, Wilen, Craig B., 2020
Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling., Israelow, Benjamin, Song, Eric, Mao, Tianyang, Lu, Peiwen, Meir, Amit, Liu, Feimei, Alfajaro, Mia Madel, Wei, Jin, Dong, Huiping, Homer, Robert J, Ring, Aaron, Wilen, Craig B, Iwasaki, Akiko., 2020
SNX8 modulates the innate immune response to RNA viruses by regulating the aggregation of VISA., Wei Guo, Jin Wei, Xuan Zhong, Ru Zang, Huan Lian, MingMing Hu, Shu Li, HongBing Shu, Qing Yang., 2019
Norovirus Attachment and Entry., Graziano, Vincent R, Wei, Jin, Wilen, Craig B., 2019
MARCH3 attenuates IL-1β–triggered inflammation by mediating K48-linked polyubiquitination and degradation of IL-1RI., Heng Lin, Deng Gao, MingMing Hu, Man Zhang, XiaoXia Wu, Lu Feng, WenHua Xu, Qing Yang, Xuan Zhong, Jin Wei, ZhiSheng Xu, HongXia Zhang, ZeMin Song, Qian Zhou, Wen Ye, Ying Liu, Shu Li, HongBing Shu., 2018
The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors., Lian, Huan, Zang, Ru, Wei, Jin, Ye, Wen, Hu, MingMing, Chen, YunDa, Zhang, XiaNan, Guo, Yi, Lei, CaoQi, Yang, Qing, Luo, WeiWei, Li, Shu, Shu, HongBing., 2018
