Areas of Focus
- Gene therapy technology development and optimization
- Gene editing system optimization
- Bioinformatics algorithm development
- Artificial intelligence algorithm development
Work Experience
- 2019 - Postdoctoral Researcher, Biomedical Engineering, Tongji University
- 2022 - Assistant Professor, School of Life Sciences and Technology, Tongji University
Academic Background & Achievements
- 2014 - Bachelor of Engineering in Bioinformatics, Tongji University
- 2019 - PhD in Biology, Tongji University
- Published 10 SCI papers, 6 as first or corresponding author
- Filed 1 patent, contributed to 1 book chapter
Publications
- DeepCRISPR: optimized CRISPR guide RNA design by deep learning, Chuai G, Ma H, Yan J, et al., 2018
- In Silico Meets In Vivo: Towards Computational CRISPR-Based sgRNA Design, Chuai G, Wang Q, Liu Q, 2017
- Deciphering relationship between microhomology and in-frame mutation occurrence in human CRISPR-based gene knockout, Chuai G, Yang F, Yan J, et al., 2016
- Benchmarking CRISPR on-target sgRNA design, Yan J, Chuai G, Zhou C, et al., 2018
- MetaTopics: an integration tool to analyze microbial community profile by topic model, Yan J, Chuai G, Qi T, et al., 2017
- Data imbalance in CRISPR off-target prediction, Gao Y, Chuai G, Yu W, et al., 2020
- Benchmarking and integrating genome-wide CRISPR off-target detection and prediction, Yan J, Xue D, Chuai G, et al., 2020
- Learning for single-cell assignment, Duan B, Zhu C, Chuai G, et al., 2020
- DeepReac+: deep active learning for quantitative modeling of organic chemical reactions, Gong Y, Xue D, Chuai G, et al., 2021
- FL-QSAR: a federated learning-based QSAR prototype for collaborative drug discovery, Chen S, Xue D, Chuai G, et al., 2021
