Areas of Focus
- Epigenetic regulatory mechanisms in cell fate transitions
- Development of deep learning algorithms for single-cell and spatial multi-omics
Work Experience
- 2018 - Present - Tongji University, School of Life Sciences and Technology, Associate Professor
Academic Background & Achievements
- Bachelor and Master in Computer Science and Technology from Central South University
- PhD in Bioinformatics from Technical University of Munich, 2017
- Leads multiple national research projects including the National Natural Science Foundation of China
Publications
- Unique Patterns of H3K4me3 and H3K27me3 in 2-Cell-like Embryonic Stem Cells, Y. Zhang et al., 2021
- Dcaf11 activates Zscan4-mediated alternative telomere lengthening in early embryos and embryonic stem cells, R. Le et al., 2020
- Precise temporal regulation of Dux is important for embryo development, M. Guo et al., 2019
- Distinct H3K9me3 and DNA methylation modifications during mouse spermatogenesis, Y. Liu et al., 2019
- Genome-wide analysis of somatic copy number alterations and chromosomal breakages in osteosarcoma, J. Smida et al., 2017
- Genomic determinants of somatic copy number alterations across human cancers, Y. Zhang et al., 2016
