Xiaocui Xu
Life Science
Tongji University
Shanghai
Language: Chinese, English
Contact
Epigenetics Stem Cells Embryonic Development Cell Fate Bioinformatics Algorithm Development Multi-Omics Dna Methylation Histone Modification Transcriptomics
Areas of Focus
  • Epigenetic regulation mechanisms in stem cells and embryonic development
  • Integration and algorithm development for multi-omics data
Work Experience
  • 2019.9-2020.4 - Tongji University, School of Life Sciences and Technology - Assistant Researcher
  • 2020.5-2023.2 - Tongji University, School of Life Sciences and Technology - Postdoctoral Fellow
  • 2023.3-present - Tongji University, School of Life Sciences and Technology - Associate Professor
Academic Background & Achievements
  • 2007.9-2011.6 Bachelor: China Medical University, Life Science and Technology
  • 2011.9-2019.6 PhD: Chinese Academy of Sciences, Beijing Institute of Genomics
  • Published research in Nature Cell Biology, National Science Review, Protein & Cell
Publications
  • N6-methyladenosine regulates maternal RNA maintenance in oocytes and timely RNA decay during mouse maternal-to-zygotic transition, You Wu, Xiaocui Xu, Meijie Qi, Chuan Chen, Mengying Li, Rushuang Yan, Xiaochen Kou, Yanhong Zhao, Wenqiang Liu, Yanhe Li, Xuelian Liu, Meiling Zhang, Chengqi Yi, Hongbin Liu, Junhong Xiang, Hong Wang, Bin Shen, Yawei Gao, Shaorong Gao, 2022
  • Aberrant nucleosome organization in mouse SCNT embryos revealed by ULI-MNase-seq, Lingyue Yang, Xiaocui Xu, Ruimin Xu, Chuan Chen, Xiaolei Zhang, Mo Chen, Xiaochen Kou, Yanhong Zhao, Hong Wang, Xiaoyu Liu, Shaorong Gao, Chong Li, 2022
  • Bilineage embryo-like structure from EPS cells can produce live mice with tetraploid trophectoderm, Kuisheng Liu, Xiaocui Xu, Dandan Bai, Yanhe Li, Yalin Zhang, Yanping Jia, Mingyue Guo, Xiaoxiao Han, Yingdong Liu, Yifan Sheng, Xiaochen Kou, Yanhong Zhao, Jiqing Yin, Sheng Liu, Jiayu Chen, Hong Wang, Yixuan Wang, Wenqiang Liu, Shaorong Gao, 2022
  • Evolutionary transition between invertebrates and vertebrates via methylation reprogramming in embryogenesis, Xiaocui Xu, Guoqiang Li, Congru Li, Jing Zhang, Qiang Wang, David K. Simmons, Xuepeng Chen, Naveen Wijesena, Wei Zhu, Zhanyang Wan, Zhenhua Wan, Bao Ju, Weimin Ci, Xuemei Lu, Daqi Yu, Qi an-fei Wang, Neelakanteswar Aluru, Paola Oliveri, Yong E. Zhang, Mark Q. Martindale, Jiang Liu, 2019
  • DNA methylation reprogramming of functional elements during mammalian embryonic development, Congru Li, Yong Fan, Guoqiang Li, Xiaocui Xu, Jialei Duan, Rong Li, Xiangjin Kang, Xin Ma, Xuepeng Chen, Yuwen Ke, Jie Yan, Ying Lian, Ping Liu, Yue Zhao, Hongcui Zhao, Yaoyong Chen, Yan g Yu, Jiang Liu, 2018
Awards
  • 2021.01-2023.12: National Natural Science Foundation of China, Young Scientist Fund, Principal Investigator
  • 2021.06-2023.05: China Postdoctoral Science Foundation Grant, Principal Investigator
  • 2023.01-2026.12: National Natural Science Foundation of China, Principal Investigator
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