Professor | Hao Ying | Asia Growth Partners

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Name	Hao Ying
Contact Information	yinghao@sibs.ac.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Hao Ying

Contact Information

yinghao@sibs.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	1996-09--2001-08 PhD: Shanghai Institute of Cell Biology, Chinese Academy of Sciences 1992-09--1996-07 Bachelor: East China University of Science and Technology
Work Experience	2020-04~Present - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Researcher, Group Leader 2008-07~2020-03 - Shanghai Institute of Nutrition Sciences, Chinese Academy of Sciences - Researcher, Group Leader 2006-12~2008-07 - National Institutes of Health, US - Staff Scientist 2001-12~2006-12 - National Institutes of Health, US - Postdoctoral Fellow
Awards	Hua Xia Medical Science and Technology Award (2023): Third Prize Oriental Talent Leading Project (2022): Provincial Level

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

1996-09--2001-08 PhD: Shanghai Institute of Cell Biology, Chinese Academy of Sciences
1992-09--1996-07 Bachelor: East China University of Science and Technology

Work Experience

2020-04~Present - Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences - Researcher, Group Leader
2008-07~2020-03 - Shanghai Institute of Nutrition Sciences, Chinese Academy of Sciences - Researcher, Group Leader
2006-12~2008-07 - National Institutes of Health, US - Staff Scientist
2001-12~2006-12 - National Institutes of Health, US - Postdoctoral Fellow

Awards

Hua Xia Medical Science and Technology Award (2023): Third Prize
Oriental Talent Leading Project (2022): Provincial Level

Areas of Focus	Thyroid hormone regulation of metabolism and thyroid-related diseases
Publications	Aberrant elevation of FTO levels promotes liver steatosis by decreasing the m(6)A methylation and increasing the stability of SREBF1 and ChREBP mRNAs, Hao Ying, 2023 Iodide Excess Inhibits Thyroid Hormone Synthesis Pathway Involving XBP1-Mediated Regulation, Hao Ying, 2023 Adipocyte Thyroid Hormone beta Receptor-Mediated Hormone Action Fine-tunes Intracellular Glucose and Lipid Metabolism and Systemic Homeostasis, Hao Ying, 2023 Hepatic thyroid hormone signalling modulates glucose homeostasis through the regulation of GLP-1 production via bile acid-mediated FXR antagonism, Hao Ying, 2022 Hepatic p38 Activation Modulates Systemic Metabolism Through FGF21-Mediated Interorgan Communication, Hao Ying, 2022 miR-182 targeting reprograms tumor-associated macrophages and limits breast cancer progression, Hao Ying, 2022 Triiodothyronine (T3) promotes brown fat hyperplasia via thyroid hormone receptor mediated adipocyte progenitor cell proliferation, Hao Ying, 2022 High-protein diet prevents fat mass increase after dieting by counteracting Lactobacillus-enhanced lipid absorption, Hao Ying, 2022 l-Arabinose suppresses gluconeogenesis through modulating AMP-activated protein kinase in metabolic disorder mice, Hao Ying, 2021 Saringosterol from Sargassum fusiforme Modulates Cholesterol Metabolism and Alleviates Atherosclerosis in ApoE-Deficient Mice, Hao Ying, 2021 Functional ingredients present in whole-grain foods as therapeutic tools to counteract obesity: Effects on brown and white adipose tissues, Hao Ying, 2021 Hepatic miR-378 modulates serum cholesterol levels by regulating hepatic bile acid synthesis, Hao Ying, 2021 miR-183 and miR-96 orchestrate both glucose and fat utilization in skeletal muscle, Hao Ying, 2021 miR-130b inhibits proliferation and promotes differentiation in myocytes via targeting Sp1, Hao Ying, 2021 Activation of GCN2/ATF4 signals in amygdalar PKC-delta neurons promotes WAT browning under leucine deprivation, Hao Ying, 2020 Autophagy inhibition prevents glucocorticoid-increased adiposity via suppressing BAT whitening, Hao Ying, 2020 Overexpression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling, Hao Ying, 2020 MRG15 orchestrates rhythmic epigenomic remodelling and controls hepatic lipid metabolism, Hao Ying, 2020 Sarm1 Gene Deficiency Attenuates Diabetic Peripheral Neuropathy in Mice, Hao Ying, 2019 Gain-of-Function Mutations of SLC16A11 Contribute to the Pathogenesis of Type 2 Diabetes, Hao Ying, 2019 Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis, Hao Ying, 2019 Elevated Serum Growth Differentiation Factor 15 Levels in Hyperthyroid Patients, Hao Ying, 2019 Sarm1 Gene Deficiency Attenuates Diabetic Peripheral Neuropathy in Mice, Hao Ying, 2019 Hepatic c-Jun regulates glucose metabolism via FGF21 and modulates body temperature through the neural signals, Hao Ying, 2019 Elevated serum neuregulin 4 levels in patients with hyperthyroidism, Hao Ying, 2019 Geniposide Improves Glucose Homeostasis via Regulating FoxO1/PDK4 in Skeletal Muscle, Hao Ying, 2019 Phosphorylation and Enzymatic Hydrolysis with Alcalase and Papain Effectively Reduce Allergic Reactions to Gliadins in Normal Mice, Hao Ying, 2019 SGK1/FOXO3 Signaling in Hypothalamic POMC Neurons Mediates Glucocorticoid-Increased Adiposity, Hao Ying, 2018 Effects of Geniposide from Gardenia Fruit Pomace on Skeletal-Muscle Fibrosis, Hao Ying, 2018 Effects of functional beta-glucan on proliferation, differentiation, metabolism and its anti-fibrosis properties in muscle cells, Hao Ying, 2018 Metabolic benefits of inhibition of p38 alpha in white adipose tissue in obesity, Hao Ying, 2018 Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator inHepatic Differentiation of Human Pluripotent Stem Cells, Hao Ying, 2018 miR-24 and miR-122 Negatively Regulate the Transforming Growth Factor-β/Smad Signaling Pathway in Skeletal Muscle Fibrosis, Hao Ying, 2018 microRNA-378 promotes autophagy and inhibits apoptosis in skeletal muscle, Hao Ying, 2018 Effect of V-Pits on the Property of GaN Epilayer Grown by Metalorganic Chemical Vapor Deposition, Hao Ying, 2018 Effects of functional beta-glucan on proliferation, differentiation, metabolism and its anti-fibrosis properties in muscle cells, Hao Ying, 2018 miR-24 and miR-122 Negatively Regulate the Transforming Growth Factor-beta/Smad Signaling Pathway in Skeletal Muscle Fibrosis, Hao Ying, 2018 RIPK3 Mediates Necroptosis during Embryonic Development and Postnatal Inflammation in Fadd-Deficient Mice, Hao Ying, 2017 RIP1 kinase activity-dependent roles in embryonic development of Fadd -deficient mice, Hao Ying, 2017 ATF4/ATG5 Signaling in Hypothalamic Proopiomelanocortin Neurons Regulates Fat Mass via Affecting Energy Expenditure, Hao Ying, 2017 miR-146a-5p acts as a negative regulator of TGF-β signaling in skeletal muscle after acute contusion, Hao Ying, 2017 Ligand-dependent corepressor (LCoR) represses the transcription factor C/EBPβ during early adipocyte differentiation, Hao Ying, 2017 Hemin Improves Insulin Sensitivity and Lipid Metabolism in Cultured Hepatocytes and Mice Fed a High-Fat Diet, Hao Ying, 2017 Deficiency of p38 in macrophage ameliorates d-galactosamine/TNF--induced acute liver injury in mice, Hao Ying, 2017 microRNA and thyroid hormone signaling in cardiac and skeletal muscle, Hao Ying, 2017 microRNA and thyroid hormone signaling in cardiac and skeletal muscle, Hao Ying, 2017 miR-146a-5p acts as a negative regulator of TGF-beta signaling in skeletal muscle after acute contusion, Hao Ying, 2017 Circulating microRNA-1a is a biomarker of Graves' disease patients with atrial fibrillation, Hao Ying, 2017 miR-146a-5p acts as a negative regulator of TGF-β signaling in skeletal muscle after acute contusion, Hao Ying, 2017 An ATF4-ATG5 signaling in hypothalamic POMC neurons regulates obesity, Hao Ying, 2017 AICAR enhances insulin signaling via downregulation of miR-29, Hao Ying, 2016 Prevention of Muscle Wasting by CRISPR/Cas9-mediated Disruption of Myostatin In Vivo, Hao Ying, 2016 CaMKK2 Suppresses Muscle Regeneration through the Inhibition of Myoblast Proliferation and Differentiation, Hao Ying, 0201

Areas of Focus

Thyroid hormone regulation of metabolism and thyroid-related diseases

Publications

Aberrant elevation of FTO levels promotes liver steatosis by decreasing the m(6)A methylation and increasing the stability of SREBF1 and ChREBP mRNAs, Hao Ying, 2023
Iodide Excess Inhibits Thyroid Hormone Synthesis Pathway Involving XBP1-Mediated Regulation, Hao Ying, 2023
Adipocyte Thyroid Hormone beta Receptor-Mediated Hormone Action Fine-tunes Intracellular Glucose and Lipid Metabolism and Systemic Homeostasis, Hao Ying, 2023
Hepatic thyroid hormone signalling modulates glucose homeostasis through the regulation of GLP-1 production via bile acid-mediated FXR antagonism, Hao Ying, 2022
Hepatic p38 Activation Modulates Systemic Metabolism Through FGF21-Mediated Interorgan Communication, Hao Ying, 2022
miR-182 targeting reprograms tumor-associated macrophages and limits breast cancer progression, Hao Ying, 2022
Triiodothyronine (T3) promotes brown fat hyperplasia via thyroid hormone receptor mediated adipocyte progenitor cell proliferation, Hao Ying, 2022
High-protein diet prevents fat mass increase after dieting by counteracting Lactobacillus-enhanced lipid absorption, Hao Ying, 2022
l-Arabinose suppresses gluconeogenesis through modulating AMP-activated protein kinase in metabolic disorder mice, Hao Ying, 2021
Saringosterol from Sargassum fusiforme Modulates Cholesterol Metabolism and Alleviates Atherosclerosis in ApoE-Deficient Mice, Hao Ying, 2021
Functional ingredients present in whole-grain foods as therapeutic tools to counteract obesity: Effects on brown and white adipose tissues, Hao Ying, 2021
Hepatic miR-378 modulates serum cholesterol levels by regulating hepatic bile acid synthesis, Hao Ying, 2021
miR-183 and miR-96 orchestrate both glucose and fat utilization in skeletal muscle, Hao Ying, 2021
miR-130b inhibits proliferation and promotes differentiation in myocytes via targeting Sp1, Hao Ying, 2021
Activation of GCN2/ATF4 signals in amygdalar PKC-delta neurons promotes WAT browning under leucine deprivation, Hao Ying, 2020
Autophagy inhibition prevents glucocorticoid-increased adiposity via suppressing BAT whitening, Hao Ying, 2020
Overexpression of Smad7 in hypothalamic POMC neurons disrupts glucose balance by attenuating central insulin signaling, Hao Ying, 2020
MRG15 orchestrates rhythmic epigenomic remodelling and controls hepatic lipid metabolism, Hao Ying, 2020
Sarm1 Gene Deficiency Attenuates Diabetic Peripheral Neuropathy in Mice, Hao Ying, 2019
Gain-of-Function Mutations of SLC16A11 Contribute to the Pathogenesis of Type 2 Diabetes, Hao Ying, 2019
Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis, Hao Ying, 2019
Elevated Serum Growth Differentiation Factor 15 Levels in Hyperthyroid Patients, Hao Ying, 2019
Sarm1 Gene Deficiency Attenuates Diabetic Peripheral Neuropathy in Mice, Hao Ying, 2019
Hepatic c-Jun regulates glucose metabolism via FGF21 and modulates body temperature through the neural signals, Hao Ying, 2019
Elevated serum neuregulin 4 levels in patients with hyperthyroidism, Hao Ying, 2019
Geniposide Improves Glucose Homeostasis via Regulating FoxO1/PDK4 in Skeletal Muscle, Hao Ying, 2019
Phosphorylation and Enzymatic Hydrolysis with Alcalase and Papain Effectively Reduce Allergic Reactions to Gliadins in Normal Mice, Hao Ying, 2019
SGK1/FOXO3 Signaling in Hypothalamic POMC Neurons Mediates Glucocorticoid-Increased Adiposity, Hao Ying, 2018
Effects of Geniposide from Gardenia Fruit Pomace on Skeletal-Muscle Fibrosis, Hao Ying, 2018
Effects of functional beta-glucan on proliferation, differentiation, metabolism and its anti-fibrosis properties in muscle cells, Hao Ying, 2018
Metabolic benefits of inhibition of p38 alpha in white adipose tissue in obesity, Hao Ying, 2018
Genetic and Chemical Screenings Identify HDAC3 as a Key Regulator inHepatic Differentiation of Human Pluripotent Stem Cells, Hao Ying, 2018
miR-24 and miR-122 Negatively Regulate the Transforming Growth Factor-β/Smad Signaling Pathway in Skeletal Muscle Fibrosis, Hao Ying, 2018
microRNA-378 promotes autophagy and inhibits apoptosis in skeletal muscle, Hao Ying, 2018
Effect of V-Pits on the Property of GaN Epilayer Grown by Metalorganic Chemical Vapor Deposition, Hao Ying, 2018
Effects of functional beta-glucan on proliferation, differentiation, metabolism and its anti-fibrosis properties in muscle cells, Hao Ying, 2018
miR-24 and miR-122 Negatively Regulate the Transforming Growth Factor-beta/Smad Signaling Pathway in Skeletal Muscle Fibrosis, Hao Ying, 2018
RIPK3 Mediates Necroptosis during Embryonic Development and Postnatal Inflammation in Fadd-Deficient Mice, Hao Ying, 2017
RIP1 kinase activity-dependent roles in embryonic development of Fadd -deficient mice, Hao Ying, 2017
ATF4/ATG5 Signaling in Hypothalamic Proopiomelanocortin Neurons Regulates Fat Mass via Affecting Energy Expenditure, Hao Ying, 2017
miR-146a-5p acts as a negative regulator of TGF-β signaling in skeletal muscle after acute contusion, Hao Ying, 2017
Ligand-dependent corepressor (LCoR) represses the transcription factor C/EBPβ during early adipocyte differentiation, Hao Ying, 2017
Hemin Improves Insulin Sensitivity and Lipid Metabolism in Cultured Hepatocytes and Mice Fed a High-Fat Diet, Hao Ying, 2017
Deficiency of p38 in macrophage ameliorates d-galactosamine/TNF--induced acute liver injury in mice, Hao Ying, 2017
microRNA and thyroid hormone signaling in cardiac and skeletal muscle, Hao Ying, 2017
microRNA and thyroid hormone signaling in cardiac and skeletal muscle, Hao Ying, 2017
miR-146a-5p acts as a negative regulator of TGF-beta signaling in skeletal muscle after acute contusion, Hao Ying, 2017
Circulating microRNA-1a is a biomarker of Graves' disease patients with atrial fibrillation, Hao Ying, 2017
miR-146a-5p acts as a negative regulator of TGF-β signaling in skeletal muscle after acute contusion, Hao Ying, 2017
An ATF4-ATG5 signaling in hypothalamic POMC neurons regulates obesity, Hao Ying, 2017
AICAR enhances insulin signaling via downregulation of miR-29, Hao Ying, 2016
Prevention of Muscle Wasting by CRISPR/Cas9-mediated Disruption of Myostatin In Vivo, Hao Ying, 2016
CaMKK2 Suppresses Muscle Regeneration through the Inhibition of Myoblast Proliferation and Differentiation, Hao Ying, 0201

Thyroid Hormone Metabolism Thyroid Diseases Regulation Research Health Endocrinology Pathophysiology Biochemistry Cell Biology

Fanglin Sun - Tongji University

Wen Chen - Tongji University

Xiling Du - Tongji University

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