Professor | Zhuang Yibin | Asia Growth Partners

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Name	Zhuang Yibin
Contact Information	zhuang_yb@tib.cas.cn
Language ability	Chinese, English
Province	Tianjin

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Name

Zhuang Yibin

Contact Information

zhuang_yb@tib.cas.cn

Language ability

Chinese, English

Province

Tianjin

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2006-09--2011-06 PhD: Ocean University of China 2002-09--2006-06 Bachelor's: Yantai University
Work Experience	2011-08~Present - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Assistant Researcher, Associate Researcher 2006-09~2011-06 - Ocean University of China - PhD Student 2002-09~2006-06 - Yantai University - Bachelor's Student

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2006-09--2011-06 PhD: Ocean University of China
2002-09--2006-06 Bachelor's: Yantai University

Work Experience

2011-08~Present - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Assistant Researcher, Associate Researcher
2006-09~2011-06 - Ocean University of China - PhD Student
2002-09~2006-06 - Yantai University - Bachelor's Student

Areas of Focus	Biotechnology Genetic Engineering Microbial Synthesis Natural Product Biosynthesis Metabolic Engineering Synthetic Biology Enzyme Engineering Fermentation Technology Protein Engineering Bioinformatics
Publications	Identification of a highly promiscuous glucosyltransferase from Penstemon barbatus for natural product glycodiversification, Third Author, 2023 Anti-fouling tight ultrafiltration membrane for gastrodin purification, Third Author, 2023 Two O-Methyltransferases Mediate Multiple Methylation Steps in the Biosynthesis of Coumarins in Cnidium monnieri, Third Author, 2022 Biosynthesis of a rosavin natural product in Escherichia coli by glycosyltransferase rational design and artificial pathway construction, Fourth Author, 2022 Advances in microbial synthesis of plant natural products, Fifth Author, 2022 Biosynthesis of cinnamyl acetate by three plant-derived benzyl acyltransferases in engineered Escherichia coli, Fifth Author, 2021 CYP82AR Subfamily Proteins Catalyze C-1 ' Hydroxylations of Deoxyshikonin in the Biosynthesis of Shikonin and Alkannin, Second Author, 2021 Advances in microbial synthesis of plant natural products, First Author, 2021 Production of caffeyl alcohol glucosides by mixed fermentation with different Escherichia coli recombinants, Second Author, 2020 Potential role of two cytochrome P450s obtained from Lithospermum erythrorhizon in catalyzing the oxidation of geranylhydroquinone during Shikonin biosynthesis, Second Author, 2020 Metabolic engineering of Saccharomyces cerevisiae for high-level production of gastrodin from glucose, Third Author, 2020 Raising the production of phloretin by alleviation of by-product of chalcone synthase in the engineered yeast, Fifth Author, 2020 Producing Gram-Scale Unnatural Rosavin Analogues from Glucose by Engineered Escherichia coli, Fourth Author, 2019 Production of caffeoylmalic acid from glucose in engineered Escherichia coli, Fourth Author, 2018 Metabolic Engineering of Saccharomyces cerevisiae for High-Level Production of Salidroside from Glucose, Fourth Author, 2018 Production of Cinnamyl Alcohol Glucoside from Glucose in Escherichia coli, Third Author, 2017 Biosynthesis of 3-(4-Hydroxyphenyl)Propionic Acid in Saccharomyces cerevisiae, Second Author, 2017 Fermentative Production of Phenolic Glucosides by Escherichia coli with an Engineered Glucosyltransferase from Rhodiola sachalinensis, Seventh Author, 2017 Biocatalysis of Phenolic Glycosides Natural Products in Escherichia coli Strain Using UGT73B6, Sixth Author, 2017 Biosynthesis of Valerena-4,7(11)-diene in an Engineered Escherichia coli Strain, Third Author, 2017 Biosynthesis of 3,4-dihydroxymandelic Acid in an Engineered Escherichia coli Strain, Third Author, 2017 De novo biosynthesis of Gastrodin in Escherichia coli, Fourth Author, 2016 Synthesis of rosmarinic acid analogues in Escherichia coli, First Author, 2016 Biosynthesis of phlorisovalerophenone and 4-hydroxy-6-isobutyl-2-pyrone in Escherichia coli from glucose, Second Author, 2016 Engineered synthesis of rosmarinic acid in Escherichia coli resulting production of a new intermediate, caffeoyl-phenyllactate, Third Author, 2016 Heterologous expression of bottromycin biosynthetic gene cluster and increase of yield, Seventh Author, 2015 Heterologous biosynthesis of costunolide in Escherichia coli and yield improvement, Second Author, 2015 Three New Xanthones from the Fungus Penicillium sp NH-7-1, First Author, 2015 The preliminary identification of piloquinone biosynthetic gene cluster, Fourth Author, 2014 Production of salidroside in metabolically engineered Escherichia coli, Third Author, 2014 Draft Genome Sequence of Streptomyces bottropensisATCC 25435, a Bottromycin-Producing Actinomycete, Third Author, 2013 Engineered short branched-chain acyl-CoA synthesis inE. coliand acylation of chloramphenicol to branched-chain derivatives, Fourth Author, 2013 Engineered short branched-chain acyl-CoA synthesis in E-coli and acylation of chloramphenicol to branched-chain derivatives, Fourth Author, 2013

Areas of Focus

Biotechnology
Genetic Engineering
Microbial Synthesis
Natural Product Biosynthesis
Metabolic Engineering
Synthetic Biology
Enzyme Engineering
Fermentation Technology
Protein Engineering
Bioinformatics

Publications

Identification of a highly promiscuous glucosyltransferase from Penstemon barbatus for natural product glycodiversification, Third Author, 2023
Anti-fouling tight ultrafiltration membrane for gastrodin purification, Third Author, 2023
Two O-Methyltransferases Mediate Multiple Methylation Steps in the Biosynthesis of Coumarins in Cnidium monnieri, Third Author, 2022
Biosynthesis of a rosavin natural product in Escherichia coli by glycosyltransferase rational design and artificial pathway construction, Fourth Author, 2022
Advances in microbial synthesis of plant natural products, Fifth Author, 2022
Biosynthesis of cinnamyl acetate by three plant-derived benzyl acyltransferases in engineered Escherichia coli, Fifth Author, 2021
CYP82AR Subfamily Proteins Catalyze C-1 ' Hydroxylations of Deoxyshikonin in the Biosynthesis of Shikonin and Alkannin, Second Author, 2021
Advances in microbial synthesis of plant natural products, First Author, 2021
Production of caffeyl alcohol glucosides by mixed fermentation with different Escherichia coli recombinants, Second Author, 2020
Potential role of two cytochrome P450s obtained from Lithospermum erythrorhizon in catalyzing the oxidation of geranylhydroquinone during Shikonin biosynthesis, Second Author, 2020
Metabolic engineering of Saccharomyces cerevisiae for high-level production of gastrodin from glucose, Third Author, 2020
Raising the production of phloretin by alleviation of by-product of chalcone synthase in the engineered yeast, Fifth Author, 2020
Producing Gram-Scale Unnatural Rosavin Analogues from Glucose by Engineered Escherichia coli, Fourth Author, 2019
Production of caffeoylmalic acid from glucose in engineered Escherichia coli, Fourth Author, 2018
Metabolic Engineering of Saccharomyces cerevisiae for High-Level Production of Salidroside from Glucose, Fourth Author, 2018
Production of Cinnamyl Alcohol Glucoside from Glucose in Escherichia coli, Third Author, 2017
Biosynthesis of 3-(4-Hydroxyphenyl)Propionic Acid in Saccharomyces cerevisiae, Second Author, 2017
Fermentative Production of Phenolic Glucosides by Escherichia coli with an Engineered Glucosyltransferase from Rhodiola sachalinensis, Seventh Author, 2017
Biocatalysis of Phenolic Glycosides Natural Products in Escherichia coli Strain Using UGT73B6, Sixth Author, 2017
Biosynthesis of Valerena-4,7(11)-diene in an Engineered Escherichia coli Strain, Third Author, 2017
Biosynthesis of 3,4-dihydroxymandelic Acid in an Engineered Escherichia coli Strain, Third Author, 2017
De novo biosynthesis of Gastrodin in Escherichia coli, Fourth Author, 2016
Synthesis of rosmarinic acid analogues in Escherichia coli, First Author, 2016
Biosynthesis of phlorisovalerophenone and 4-hydroxy-6-isobutyl-2-pyrone in Escherichia coli from glucose, Second Author, 2016
Engineered synthesis of rosmarinic acid in Escherichia coli resulting production of a new intermediate, caffeoyl-phenyllactate, Third Author, 2016
Heterologous expression of bottromycin biosynthetic gene cluster and increase of yield, Seventh Author, 2015
Heterologous biosynthesis of costunolide in Escherichia coli and yield improvement, Second Author, 2015
Three New Xanthones from the Fungus Penicillium sp NH-7-1, First Author, 2015
The preliminary identification of piloquinone biosynthetic gene cluster, Fourth Author, 2014
Production of salidroside in metabolically engineered Escherichia coli, Third Author, 2014
Draft Genome Sequence of Streptomyces bottropensisATCC 25435, a Bottromycin-Producing Actinomycete, Third Author, 2013
Engineered short branched-chain acyl-CoA synthesis inE. coliand acylation of chloramphenicol to branched-chain derivatives, Fourth Author, 2013
Engineered short branched-chain acyl-CoA synthesis in E-coli and acylation of chloramphenicol to branched-chain derivatives, Fourth Author, 2013

Biotechnology Genetic Engineering Microbial Synthesis Natural Products Metabolic Pathways Synthetic Biology Enzymes Fermentation Proteins Bioinformatics

Guifen Liu - Tongji University

Song Lei - Shanghai Normal University

Ruilian Yao - Shanghai Jiao Tong University

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