Upload Avatar (500 x 500)
Zhuang Yibin
Life Science
University of Chinese Academy of Sciences
Tianjin
Language: Chinese, English
Biotechnology
Genetic Engineering
Microbial Synthesis
Natural Products
Metabolic Pathways
Synthetic Biology
Enzymes
Fermentation
Proteins
Bioinformatics
Areas of Focus
- Biotechnology
- Genetic Engineering
- Microbial Synthesis
- Natural Product Biosynthesis
- Metabolic Engineering
- Synthetic Biology
- Enzyme Engineering
- Fermentation Technology
- Protein Engineering
- Bioinformatics
Work Experience
- 2011-08~Present - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Assistant Researcher, Associate Researcher
- 2006-09~2011-06 - Ocean University of China - PhD Student
- 2002-09~2006-06 - Yantai University - Bachelor's Student
Academic Background & Achievements
- 2006-09--2011-06 PhD: Ocean University of China
- 2002-09--2006-06 Bachelor's: Yantai University
Publications
- Identification of a highly promiscuous glucosyltransferase from Penstemon barbatus for natural product glycodiversification, Third Author, 2023
- Anti-fouling tight ultrafiltration membrane for gastrodin purification, Third Author, 2023
- Two O-Methyltransferases Mediate Multiple Methylation Steps in the Biosynthesis of Coumarins in Cnidium monnieri, Third Author, 2022
- Biosynthesis of a rosavin natural product in Escherichia coli by glycosyltransferase rational design and artificial pathway construction, Fourth Author, 2022
- Advances in microbial synthesis of plant natural products, Fifth Author, 2022
- Biosynthesis of cinnamyl acetate by three plant-derived benzyl acyltransferases in engineered Escherichia coli, Fifth Author, 2021
- CYP82AR Subfamily Proteins Catalyze C-1 ' Hydroxylations of Deoxyshikonin in the Biosynthesis of Shikonin and Alkannin, Second Author, 2021
- Advances in microbial synthesis of plant natural products, First Author, 2021
- Production of caffeyl alcohol glucosides by mixed fermentation with different Escherichia coli recombinants, Second Author, 2020
- Potential role of two cytochrome P450s obtained from Lithospermum erythrorhizon in catalyzing the oxidation of geranylhydroquinone during Shikonin biosynthesis, Second Author, 2020
- Metabolic engineering of Saccharomyces cerevisiae for high-level production of gastrodin from glucose, Third Author, 2020
- Raising the production of phloretin by alleviation of by-product of chalcone synthase in the engineered yeast, Fifth Author, 2020
- Producing Gram-Scale Unnatural Rosavin Analogues from Glucose by Engineered Escherichia coli, Fourth Author, 2019
- Production of caffeoylmalic acid from glucose in engineered Escherichia coli, Fourth Author, 2018
- Metabolic Engineering of Saccharomyces cerevisiae for High-Level Production of Salidroside from Glucose, Fourth Author, 2018
- Production of Cinnamyl Alcohol Glucoside from Glucose in Escherichia coli, Third Author, 2017
- Biosynthesis of 3-(4-Hydroxyphenyl)Propionic Acid in Saccharomyces cerevisiae, Second Author, 2017
- Fermentative Production of Phenolic Glucosides by Escherichia coli with an Engineered Glucosyltransferase from Rhodiola sachalinensis, Seventh Author, 2017
- Biocatalysis of Phenolic Glycosides Natural Products in Escherichia coli Strain Using UGT73B6, Sixth Author, 2017
- Biosynthesis of Valerena-4,7(11)-diene in an Engineered Escherichia coli Strain, Third Author, 2017
- Biosynthesis of 3,4-dihydroxymandelic Acid in an Engineered Escherichia coli Strain, Third Author, 2017
- De novo biosynthesis of Gastrodin in Escherichia coli, Fourth Author, 2016
- Synthesis of rosmarinic acid analogues in Escherichia coli, First Author, 2016
- Biosynthesis of phlorisovalerophenone and 4-hydroxy-6-isobutyl-2-pyrone in Escherichia coli from glucose, Second Author, 2016
- Engineered synthesis of rosmarinic acid in Escherichia coli resulting production of a new intermediate, caffeoyl-phenyllactate, Third Author, 2016
- Heterologous expression of bottromycin biosynthetic gene cluster and increase of yield, Seventh Author, 2015
- Heterologous biosynthesis of costunolide in Escherichia coli and yield improvement, Second Author, 2015
- Three New Xanthones from the Fungus Penicillium sp NH-7-1, First Author, 2015
- The preliminary identification of piloquinone biosynthetic gene cluster, Fourth Author, 2014
- Production of salidroside in metabolically engineered Escherichia coli, Third Author, 2014
- Draft Genome Sequence of Streptomyces bottropensisATCC 25435, a Bottromycin-Producing Actinomycete, Third Author, 2013
- Engineered short branched-chain acyl-CoA synthesis inE. coliand acylation of chloramphenicol to branched-chain derivatives, Fourth Author, 2013
- Engineered short branched-chain acyl-CoA synthesis in E-coli and acylation of chloramphenicol to branched-chain derivatives, Fourth Author, 2013
