Professor | Xiaokang Zhang | Asia Growth Partners

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Name	Xiaokang Zhang
Contact Information	xk.zhang@siat.ac.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Xiaokang Zhang

Contact Information

xk.zhang@siat.ac.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2001-09--2005-07 Bachelor's Degree: Sun Yat-sen University 2005-09--2009-03 Master's Degree: Sun Yat-sen University 2009-09--2012-07 PhD: University of Science and Technology of China
Work Experience	2021-01~Present - Chinese Academy of Sciences Shenzhen Institute of Advanced Technology - Professor 2020-04~2021-01 - Chinese Academy of Sciences Shenzhen Institute of Advanced Technology - Group Leader 2016-01~2020-04 - Zhejiang University - Associate Professor 2013-10~2016-01 - Pasteur Institute (Paris) - Postdoctoral Researcher 2012-10~2013-06 - European Molecular Biology Laboratory - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2001-09--2005-07 Bachelor's Degree: Sun Yat-sen University
2005-09--2009-03 Master's Degree: Sun Yat-sen University
2009-09--2012-07 PhD: University of Science and Technology of China

Work Experience

2021-01~Present - Chinese Academy of Sciences Shenzhen Institute of Advanced Technology - Professor
2020-04~2021-01 - Chinese Academy of Sciences Shenzhen Institute of Advanced Technology - Group Leader
2016-01~2020-04 - Zhejiang University - Associate Professor
2013-10~2016-01 - Pasteur Institute (Paris) - Postdoctoral Researcher
2012-10~2013-06 - European Molecular Biology Laboratory - Postdoctoral Researcher

Areas of Focus	In-situ study of protein conformation dynamics and their interactions with ligands and natural phospholipids Cryo-electron microscopy technology
Publications	Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis, Wang, Jiangqin, Yu, Xiafei, Ding, Zhong Jie, Zhang, Xiaokang, Luo, Yanping, Xu, Ximing, Xie, Yuan, Li, Xiaoxiao, Yuan, Tian, Zheng, Shao Jian, Yang, Wei, Guo, Jiangtao, 2021 The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses, Sharma, Arvind, Zhang, Xiaokang, Dejnirattisai, Wanwisa, Dai, Xinghong, Gong, Danyang, Wongwiwat, Wiyada, Duquerroy, Stephane, Rouvinski, Alexander, Vaney, MarieChristine, GuardadoCalvo, Pablo, Haouz, Ahmed, England, Patrick, Sun, Ren, Zhou, Z Hong, Mongkolsapaya, Juthathip, Screaton, Gavin R, Rey, Felix A, 2021 Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel, Yu, Xiafe, Xie, Yuan, Zhang, Xiaokang, Ma, Cheng, Liu, Likun, Zhen, Wenxuan, Xu, Lingyi, Zhang, Jianmin, Liang, Yan, Zhao, Lixia, Gao, Xiuxia, Yu, Peilin, Luo, Jianhong, Jiang, LinHua, Nie, Yan, Yang, Fan, Guo, Jiangtao, Yang, Wei, 2021 Molecular basis of ligand recognition and activation of human V2 vasopressin receptor, Fulai Zhou, Chenyu Ye, Xiaomin Ma, Wanchao Yin, Tristan ICroll, Qingtong Zhou, Xinheng He, Xiaokang Zhang, Dehua Yang, Peiyi Wang, HEric Xu, MingWei Wang, Yi Jiang, 2021 Mesophasic organization of GABA(A) receptors in hippocampal inhibitory synapses, Liu, YunTao, Tao, ChangLu, Zhang, Xiaokang, Xia, Wenjun, Shi, DongQing, Qi, Lei, Xu, Cheng, Sun, Rong, Li, XiaoWei, Lau, PakMing, Zhou, Z Hong, Bi, GuoQiang, 2020 Cooperative transport mechanism of human monocarboxylate transporter 2, Zhang, Bo, Jin, Qiuheng, Xu, Lizhen, Li, Ningning, Meng, Ying, Chang, Shenghai, Zheng, Xiang, Wang, Jiangqin, Chen, Yuan, Neculai, Dante, Gao, Ning, Zhang, Xiaokang, Yang, Fan, Guo, Jiangtao, Ye, Sheng, 2020 Cryo-EM structures of human pannexin 1 channel, Jin, Qiuheng, Zhang, Bo, Zheng, Xiang, Li, Ningning, Xu, Lingyi, Xie, Yuan, Song, Fangjun, Bhat, Eijaz Ahmed, Chen, Yuan, Gao, Ning, Guo, Jiangtao, Zhang, Xiaokang, Ye, Sheng, 2020 Cryo-EM Structure of a Begomovirus Geminate Particle, Xu, Xiongbiao, Zhang, Qing, Hong, Jian, Li, Zhenghe, Zhang, Xiaokang, Zhou, Xueping, 2019 Cryo-EM structure of the human α5β3 GABAA receptor, Liu Si, Xu Lingyi, Guan Fenghui, Liu Yuntao, Cui Yanxiang, Zhang Qing, Zheng Xiang, Bi Guoqiang, Zhou Hong Z, Zhang Xiaokang, Ye Sheng, 2018 Cryo-EM structure of the mature dengue virus at 3.5-Å resolution, Xiaokang Zhang, Peng Ge, Xuekui Yu, Jennifer M Brannan, Guoqiang Bi, Qinfen Zhang, Stan Schein, Z Hong Zhou, 2013 Low cost, high performance GPU computing solution for atomic resolution cryoEM single-particle reconstruction, Zhang, Xiaokang, Zhang, Xing, Zhou, Z Hong, 2010

Areas of Focus

In-situ study of protein conformation dynamics and their interactions with ligands and natural phospholipids
Cryo-electron microscopy technology

Publications

Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis, Wang, Jiangqin, Yu, Xiafei, Ding, Zhong Jie, Zhang, Xiaokang, Luo, Yanping, Xu, Ximing, Xie, Yuan, Li, Xiaoxiao, Yuan, Tian, Zheng, Shao Jian, Yang, Wei, Guo, Jiangtao, 2021
The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses, Sharma, Arvind, Zhang, Xiaokang, Dejnirattisai, Wanwisa, Dai, Xinghong, Gong, Danyang, Wongwiwat, Wiyada, Duquerroy, Stephane, Rouvinski, Alexander, Vaney, MarieChristine, GuardadoCalvo, Pablo, Haouz, Ahmed, England, Patrick, Sun, Ren, Zhou, Z Hong, Mongkolsapaya, Juthathip, Screaton, Gavin R, Rey, Felix A, 2021
Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel, Yu, Xiafe, Xie, Yuan, Zhang, Xiaokang, Ma, Cheng, Liu, Likun, Zhen, Wenxuan, Xu, Lingyi, Zhang, Jianmin, Liang, Yan, Zhao, Lixia, Gao, Xiuxia, Yu, Peilin, Luo, Jianhong, Jiang, LinHua, Nie, Yan, Yang, Fan, Guo, Jiangtao, Yang, Wei, 2021
Molecular basis of ligand recognition and activation of human V2 vasopressin receptor, Fulai Zhou, Chenyu Ye, Xiaomin Ma, Wanchao Yin, Tristan ICroll, Qingtong Zhou, Xinheng He, Xiaokang Zhang, Dehua Yang, Peiyi Wang, HEric Xu, MingWei Wang, Yi Jiang, 2021
Mesophasic organization of GABA(A) receptors in hippocampal inhibitory synapses, Liu, YunTao, Tao, ChangLu, Zhang, Xiaokang, Xia, Wenjun, Shi, DongQing, Qi, Lei, Xu, Cheng, Sun, Rong, Li, XiaoWei, Lau, PakMing, Zhou, Z Hong, Bi, GuoQiang, 2020
Cooperative transport mechanism of human monocarboxylate transporter 2, Zhang, Bo, Jin, Qiuheng, Xu, Lizhen, Li, Ningning, Meng, Ying, Chang, Shenghai, Zheng, Xiang, Wang, Jiangqin, Chen, Yuan, Neculai, Dante, Gao, Ning, Zhang, Xiaokang, Yang, Fan, Guo, Jiangtao, Ye, Sheng, 2020
Cryo-EM structures of human pannexin 1 channel, Jin, Qiuheng, Zhang, Bo, Zheng, Xiang, Li, Ningning, Xu, Lingyi, Xie, Yuan, Song, Fangjun, Bhat, Eijaz Ahmed, Chen, Yuan, Gao, Ning, Guo, Jiangtao, Zhang, Xiaokang, Ye, Sheng, 2020
Cryo-EM Structure of a Begomovirus Geminate Particle, Xu, Xiongbiao, Zhang, Qing, Hong, Jian, Li, Zhenghe, Zhang, Xiaokang, Zhou, Xueping, 2019
Cryo-EM structure of the human α5β3 GABAA receptor, Liu Si, Xu Lingyi, Guan Fenghui, Liu Yuntao, Cui Yanxiang, Zhang Qing, Zheng Xiang, Bi Guoqiang, Zhou Hong Z, Zhang Xiaokang, Ye Sheng, 2018
Cryo-EM structure of the mature dengue virus at 3.5-Å resolution, Xiaokang Zhang, Peng Ge, Xuekui Yu, Jennifer M Brannan, Guoqiang Bi, Qinfen Zhang, Stan Schein, Z Hong Zhou, 2013
Low cost, high performance GPU computing solution for atomic resolution cryoEM single-particle reconstruction, Zhang, Xiaokang, Zhang, Xing, Zhou, Z Hong, 2010

Protein Conformation Dynamics Ligands Phospholipids Biophysics Membrane Proteins Structure Function Cryo-Electron Microscopy Synaptic Proteins

Senfang Sui - Tsinghua University

Yong Wang - Zhejiang University

Shen Wang - Huazhong University of Science and Technology

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