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Xiaokang Zhang
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Protein Conformation
Dynamics
Ligands
Phospholipids
Biophysics
Membrane Proteins
Structure
Function
Cryo-Electron Microscopy
Synaptic Proteins
Areas of Focus
- In-situ study of protein conformation dynamics and their interactions with ligands and natural phospholipids
- Cryo-electron microscopy technology
Work Experience
- 2021-01~Present - Chinese Academy of Sciences Shenzhen Institute of Advanced Technology - Professor
- 2020-04~2021-01 - Chinese Academy of Sciences Shenzhen Institute of Advanced Technology - Group Leader
- 2016-01~2020-04 - Zhejiang University - Associate Professor
- 2013-10~2016-01 - Pasteur Institute (Paris) - Postdoctoral Researcher
- 2012-10~2013-06 - European Molecular Biology Laboratory - Postdoctoral Researcher
Academic Background & Achievements
- 2001-09--2005-07 Bachelor's Degree: Sun Yat-sen University
- 2005-09--2009-03 Master's Degree: Sun Yat-sen University
- 2009-09--2012-07 PhD: University of Science and Technology of China
Publications
- Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis, Wang, Jiangqin, Yu, Xiafei, Ding, Zhong Jie, Zhang, Xiaokang, Luo, Yanping, Xu, Ximing, Xie, Yuan, Li, Xiaoxiao, Yuan, Tian, Zheng, Shao Jian, Yang, Wei, Guo, Jiangtao, 2021
- The epitope arrangement on flavivirus particles contributes to Mab C10's extraordinary neutralization breadth across Zika and dengue viruses, Sharma, Arvind, Zhang, Xiaokang, Dejnirattisai, Wanwisa, Dai, Xinghong, Gong, Danyang, Wongwiwat, Wiyada, Duquerroy, Stephane, Rouvinski, Alexander, Vaney, MarieChristine, GuardadoCalvo, Pablo, Haouz, Ahmed, England, Patrick, Sun, Ren, Zhou, Z Hong, Mongkolsapaya, Juthathip, Screaton, Gavin R, Rey, Felix A, 2021
- Structural and functional basis of the selectivity filter as a gate in human TRPM2 channel, Yu, Xiafe, Xie, Yuan, Zhang, Xiaokang, Ma, Cheng, Liu, Likun, Zhen, Wenxuan, Xu, Lingyi, Zhang, Jianmin, Liang, Yan, Zhao, Lixia, Gao, Xiuxia, Yu, Peilin, Luo, Jianhong, Jiang, LinHua, Nie, Yan, Yang, Fan, Guo, Jiangtao, Yang, Wei, 2021
- Molecular basis of ligand recognition and activation of human V2 vasopressin receptor, Fulai Zhou, Chenyu Ye, Xiaomin Ma, Wanchao Yin, Tristan ICroll, Qingtong Zhou, Xinheng He, Xiaokang Zhang, Dehua Yang, Peiyi Wang, HEric Xu, MingWei Wang, Yi Jiang, 2021
- Mesophasic organization of GABA(A) receptors in hippocampal inhibitory synapses, Liu, YunTao, Tao, ChangLu, Zhang, Xiaokang, Xia, Wenjun, Shi, DongQing, Qi, Lei, Xu, Cheng, Sun, Rong, Li, XiaoWei, Lau, PakMing, Zhou, Z Hong, Bi, GuoQiang, 2020
- Cooperative transport mechanism of human monocarboxylate transporter 2, Zhang, Bo, Jin, Qiuheng, Xu, Lizhen, Li, Ningning, Meng, Ying, Chang, Shenghai, Zheng, Xiang, Wang, Jiangqin, Chen, Yuan, Neculai, Dante, Gao, Ning, Zhang, Xiaokang, Yang, Fan, Guo, Jiangtao, Ye, Sheng, 2020
- Cryo-EM structures of human pannexin 1 channel, Jin, Qiuheng, Zhang, Bo, Zheng, Xiang, Li, Ningning, Xu, Lingyi, Xie, Yuan, Song, Fangjun, Bhat, Eijaz Ahmed, Chen, Yuan, Gao, Ning, Guo, Jiangtao, Zhang, Xiaokang, Ye, Sheng, 2020
- Cryo-EM Structure of a Begomovirus Geminate Particle, Xu, Xiongbiao, Zhang, Qing, Hong, Jian, Li, Zhenghe, Zhang, Xiaokang, Zhou, Xueping, 2019
- Cryo-EM structure of the human α5β3 GABAA receptor, Liu Si, Xu Lingyi, Guan Fenghui, Liu Yuntao, Cui Yanxiang, Zhang Qing, Zheng Xiang, Bi Guoqiang, Zhou Hong Z, Zhang Xiaokang, Ye Sheng, 2018
- Cryo-EM structure of the mature dengue virus at 3.5-Å resolution, Xiaokang Zhang, Peng Ge, Xuekui Yu, Jennifer M Brannan, Guoqiang Bi, Qinfen Zhang, Stan Schein, Z Hong Zhou, 2013
- Low cost, high performance GPU computing solution for atomic resolution cryoEM single-particle reconstruction, Zhang, Xiaokang, Zhang, Xing, Zhou, Z Hong, 2010
