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张小康
Life Science
中国科学院大学
广东
Language: 中文, 英语
蛋白质构象
动态
配体
磷脂
生物物理学
膜蛋白
结构
功能
冷冻电镜
突触蛋白
Areas of Focus
- 原位研究蛋白构象动态及其与配体和天然磷脂的相互作用
- 冷冻电镜技术
Work Experience
- 2021-01~现在 - 中国科学院深圳先进技术研究院 - 教授
- 2020-04~2021-01 - 中国科学院深圳先进技术研究院 - 课题组长
- 2016-01~2020-04 - 浙江大学 - 副教授
- 2013-10~2016-01 - 巴斯德研究所（巴黎） - 博士后
- 2012-10~2013-06 - 欧洲分子生物学实验室 - 博士后
Academic Background & Achievements
- 2001-09--2005-07 学士学位: 中山大学
- 2005-09--2009-03 硕士学位: 中山大学
- 2009-09--2012-07 博士学位: 中国科学技术大学
Publications
- ALMT1介导的拟南芥铝抗性结构基础, Wang, Jiangqin, Yu, Xiafei, Ding, Zhong Jie, Zhang, Xiaokang, Luo, Yanping, Xu, Ximing, Xie, Yuan, Li, Xiaoxiao, Yuan, Tian, Zheng, Shao Jian, Yang, Wei, Guo, Jiangtao, 2021
- 黄病毒颗粒上的表位排列有助于Mab C10在寨卡和登革热病毒中的非凡中和广度, Sharma, Arvind, Zhang, Xiaokang, Dejnirattisai, Wanwisa, Dai, Xinghong, Gong, Danyang, Wongwiwat, Wiyada, Duquerroy, Stephane, Rouvinski, Alexander, Vaney, MarieChristine, GuardadoCalvo, Pablo, Haouz, Ahmed, England, Patrick, Sun, Ren, Zhou, Z Hong, Mongkolsapaya, Juthathip, Screaton, Gavin R, Rey, Felix A, 2021
- 人类TRPM2通道中选择性过滤器作为门的结构和功能基础, Yu, Xiafe, Xie, Yuan, Zhang, Xiaokang, Ma, Cheng, Liu, Likun, Zhen, Wenxuan, Xu, Lingyi, Zhang, Jianmin, Liang, Yan, Zhao, Lixia, Gao, Xiuxia, Yu, Peilin, Luo, Jianhong, Jiang, LinHua, Nie, Yan, Yang, Fan, Guo, Jiangtao, Yang, Wei, 2021
- 人类V2加压素受体配体识别和激活的分子基础, Fulai Zhou, Chenyu Ye, Xiaomin Ma, Wanchao Yin, Tristan ICroll, Qingtong Zhou, Xinheng He, Xiaokang Zhang, Dehua Yang, Peiyi Wang, HEric Xu, MingWei Wang, Yi Jiang, 2021
- 海马抑制性突触中GABA(A)受体的中相组织, Liu, YunTao, Tao, ChangLu, Zhang, Xiaokang, Xia, Wenjun, Shi, DongQing, Qi, Lei, Xu, Cheng, Sun, Rong, Li, XiaoWei, Lau, PakMing, Zhou, Z Hong, Bi, GuoQiang, 2020
- 人类单羧酸转运蛋白2的协同运输机制, Zhang, Bo, Jin, Qiuheng, Xu, Lizhen, Li, Ningning, Meng, Ying, Chang, Shenghai, Zheng, Xiang, Wang, Jiangqin, Chen, Yuan, Neculai, Dante, Gao, Ning, Zhang, Xiaokang, Yang, Fan, Guo, Jiangtao, Ye, Sheng, 2020
- 人类Pannexin 1通道的冷冻电镜结构, Jin, Qiuheng, Zhang, Bo, Zheng, Xiang, Li, Ningning, Xu, Lingyi, Xie, Yuan, Song, Fangjun, Bhat, Eijaz Ahmed, Chen, Yuan, Gao, Ning, Guo, Jiangtao, Zhang, Xiaokang, Ye, Sheng, 2020
- Begomovirus双生病毒颗粒的冷冻电镜结构, Xu, Xiongbiao, Zhang, Qing, Hong, Jian, Li, Zhenghe, Zhang, Xiaokang, Zhou, Xueping, 2019
- 人类α5β3 GABAA受体的冷冻电镜结构, Liu Si, Xu Lingyi, Guan Fenghui, Liu Yuntao, Cui Yanxiang, Zhang Qing, Zheng Xiang, Bi Guoqiang, Zhou Hong Z, Zhang Xiaokang, Ye Sheng, 2018
- 成熟登革热病毒的3.5-Å分辨率冷冻电镜结构, Xiaokang Zhang, Peng Ge, Xuekui Yu, Jennifer M Brannan, Guoqiang Bi, Qinfen Zhang, Stan Schein, Z Hong Zhou, 2013
- 低成本高性能GPU计算解决方案用于原子分辨率冷冻电镜单颗粒重建, Zhang, Xiaokang, Zhang, Xing, Zhou, Z Hong, 2010
