Professor | Yuan Zhang | Asia Growth Partners

Name	Yuan Zhang
Contact Information	zhangyuan@wh.iov.cn
Language ability	Chinese, English
Province	Hubei

Name

Yuan Zhang

Contact Information

zhangyuan@wh.iov.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2009-09--2014-07 PhD: Wuhan Institute of Virology, Chinese Academy of Sciences 2005-09--2009-06 Bachelor's Degree: Wuhan University
Work Experience	2017-09~Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Associate Researcher 2014-07~2017-08 - Wuhan Institute of Virology, Chinese Academy of Sciences - Assistant Researcher 2009-09~2014-07 - Wuhan Institute of Virology, Chinese Academy of Sciences - PhD 2005-09~2009-06 - Wuhan University - Bachelor's Degree

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2009-09--2014-07 PhD: Wuhan Institute of Virology, Chinese Academy of Sciences
2005-09--2009-06 Bachelor's Degree: Wuhan University

Work Experience

2017-09~Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Associate Researcher
2014-07~2017-08 - Wuhan Institute of Virology, Chinese Academy of Sciences - Assistant Researcher
2009-09~2014-07 - Wuhan Institute of Virology, Chinese Academy of Sciences - PhD
2005-09~2009-06 - Wuhan University - Bachelor's Degree

Areas of Focus	Virus Infection and Host Immunity Fluorescent Labeling and Real-time Tracking of Viruses Virus Vaccine Development
Publications	Development of a biosensor assessing SARS-CoV-2 main protease proteolytic activity in living cells for antiviral drugs screening, Yuan Zhang, 2022 Metabolic labeling of enterovirus 71 with quantum dots for the study of virus receptor usage, Yuan Zhang, 2021 A Single Mutation in the VP1 Gene of Enterovirus 71 Enhances Viral Binding to Heparan Sulfate and Impairs Viral Pathogenicity in Mice, Yuan Zhang, 2020 Epidemiological, Clinical and Serological Characteristics of Children with Coronavirus Disease 2019 in Wuhan: A Single-centered, Retrospective Study, Yuan Zhang, 2020 Baculovirus Surface Display of Zika Virus Envelope Protein Protects against Virus Challenge in Mouse Model, Yuan Zhang, 2020 In vivo imaging of Zika virus reveals dynamics of viral invasion in immune-sheltered tissues and vertical propagation during pregnancy, Yuan Zhang, 2020 Zika virus promotes CCN1 expression via the CaMKII alpha-CREB pathway in astrocytes, Yuan Zhang, 2020 Viperin Inhibits Enterovirus A71 Replication by Interacting with Viral 2C Protein, Yuan Zhang, 2019 ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells, Yuan Zhang, 2018 Spycatcher-spytag mediated in situ labelling of progeny baculovirus with quantum dots for tracking viral infection in living cells, Yuan Zhang, 2018 Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models, Yuan Zhang, 2018 The 3C protease of enterovirus A71 counteracts the activity of host zinc-finger antiviral protein (ZAP), Yuan Zhang, 2018 An improved method for identifying SUMOylation sites of viral proteins, Yuan Zhang, 2017 Mir-16-5p mediates a positive feedback loop in ev71-induced apoptosis and suppresses virus replication, Yuan Zhang, 2017 Fast and sensitive quantification of protein sumoylation using a dual luciferase biosensor, Yuan Zhang, 2017 Development of a luciferase-based biosensor to assess enterovirus 71 3C protease activity in living cells, Yuan Zhang, 2017 SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D To Facilitate Viral Replication, Yuan Zhang, 2016 Identification of AcMNPV GP64-binding proteins through a combinational use of a self-biotinylated virus and the cross-linking method, Yuan Zhang, 2015 Self-biotinylation and site-specific double labeling of baculovirus using quantum dots for single-virus in-situ tracking, Yuan Zhang, 2013 Encapsulating Quantum Dots into Enveloped Virus in Living Cells for Tracking Virus Infection, Yuan Zhang, 2013 One-Pot Synthesized Aptamer-Functionalized CdTe:Zn2+ Quantum Dots for Tumor-Targeted Fluorescence Imaging in Vitro and in Vivo, Yuan Zhang, 2013 Differential stepwise evolution of SARS coronavirus functional proteins in different host species, Yuan Zhang, 2009

Areas of Focus

Virus Infection and Host Immunity
Fluorescent Labeling and Real-time Tracking of Viruses
Virus Vaccine Development

Publications

Development of a biosensor assessing SARS-CoV-2 main protease proteolytic activity in living cells for antiviral drugs screening, Yuan Zhang, 2022
Metabolic labeling of enterovirus 71 with quantum dots for the study of virus receptor usage, Yuan Zhang, 2021
A Single Mutation in the VP1 Gene of Enterovirus 71 Enhances Viral Binding to Heparan Sulfate and Impairs Viral Pathogenicity in Mice, Yuan Zhang, 2020
Epidemiological, Clinical and Serological Characteristics of Children with Coronavirus Disease 2019 in Wuhan: A Single-centered, Retrospective Study, Yuan Zhang, 2020
Baculovirus Surface Display of Zika Virus Envelope Protein Protects against Virus Challenge in Mouse Model, Yuan Zhang, 2020
In vivo imaging of Zika virus reveals dynamics of viral invasion in immune-sheltered tissues and vertical propagation during pregnancy, Yuan Zhang, 2020
Zika virus promotes CCN1 expression via the CaMKII alpha-CREB pathway in astrocytes, Yuan Zhang, 2020
Viperin Inhibits Enterovirus A71 Replication by Interacting with Viral 2C Protein, Yuan Zhang, 2019
ZIKV infection activates the IRE1-XBP1 and ATF6 pathways of unfolded protein response in neural cells, Yuan Zhang, 2018
Spycatcher-spytag mediated in situ labelling of progeny baculovirus with quantum dots for tracking viral infection in living cells, Yuan Zhang, 2018
Zika Virus Attenuation by Codon Pair Deoptimization Induces Sterilizing Immunity in Mouse Models, Yuan Zhang, 2018
The 3C protease of enterovirus A71 counteracts the activity of host zinc-finger antiviral protein (ZAP), Yuan Zhang, 2018
An improved method for identifying SUMOylation sites of viral proteins, Yuan Zhang, 2017
Mir-16-5p mediates a positive feedback loop in ev71-induced apoptosis and suppresses virus replication, Yuan Zhang, 2017
Fast and sensitive quantification of protein sumoylation using a dual luciferase biosensor, Yuan Zhang, 2017
Development of a luciferase-based biosensor to assess enterovirus 71 3C protease activity in living cells, Yuan Zhang, 2017
SUMO Modification Stabilizes Enterovirus 71 Polymerase 3D To Facilitate Viral Replication, Yuan Zhang, 2016
Identification of AcMNPV GP64-binding proteins through a combinational use of a self-biotinylated virus and the cross-linking method, Yuan Zhang, 2015
Self-biotinylation and site-specific double labeling of baculovirus using quantum dots for single-virus in-situ tracking, Yuan Zhang, 2013
Encapsulating Quantum Dots into Enveloped Virus in Living Cells for Tracking Virus Infection, Yuan Zhang, 2013
One-Pot Synthesized Aptamer-Functionalized CdTe:Zn2+ Quantum Dots for Tumor-Targeted Fluorescence Imaging in Vitro and in Vivo, Yuan Zhang, 2013
Differential stepwise evolution of SARS coronavirus functional proteins in different host species, Yuan Zhang, 2009

Virus Infection Host Immunity Fluorescent Labeling Tracking Vaccine Development Research

Changdong Lin - Tongji University

Jian-Guo Cao - Shanghai Normal University

Xiaoli Wang - Shanghai Normal University

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