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Yue Zhang
Life Science
University of Chinese Academy of Sciences
Tianjin
Language: Chinese, English
Screening
Erythromycin
Crispr
Microfluidics
Biosensors
Streptomyces
Genetics
Metabolic
Synthetic
Biotechnology
Areas of Focus
- High-throughput screening methods
- Erythromycin production
- CRISPR/Cas9 technology
- Microfluidic platforms
- Biosensors
- Streptomyces genetics
- Metabolic engineering
- Synthetic biology
- Biotechnology
- Industrial microbiology
Work Experience
- 2021-06 to Present - Chinese Academy of Sciences, Tianjin Institute of Industrial Biotechnology - Associate Researcher
- 2017-07 to 2021-06 - Chinese Academy of Sciences, Tianjin Institute of Industrial Biotechnology - Assistant Researcher
- 2011-09 to 2017-06 - Tianjin University - PhD
- 2007-09 to 2011-06 - Nankai University - Bachelor
Academic Background & Achievements
- 2011-09 to 2017-06 PhD: Tianjin University
- 2007-09 to 2011-06 Bachelor: Nankai University
Publications
- CRISPR/Cas9-Mediated Multi-Locus Promoter Engineering in ery Cluster to Improve Erythromycin Production in Saccharopolyspora erythraea, 11th Author, 2023
- Product-driven high-throughput screening of industrial filamentous actinomycetes, 11th Author, 2023
- Modulating Sensitivity of an Erythromycin Biosensor for Precise High-Throughput Screening of Strains with Different Characteristics, 11th Author, 2023
- Repurposing conformational changes in ANL superfamily enzymes to rapidly generate biosensors for organic and amino acids, 6th Author, 2023
- Whole-cell biosensor and producer co-cultivation based microfludic platform for screening Saccharopolyspora erythraea with hyper erythromycin production, 11th Author, 2022
- Droplet-Microfluidic-Based Promoter Engineering and Expression Fine-Tuning for Improved Erythromycin Production in Saccharopolyspora erythraea NRRL 23338, 2nd Author, 2022
- A CRISPR/dCas9-assisted system to clone toxic genes in Escherichia coli, 2nd Author, 2021
- Antisense RNA Interference-Enhanced CRISPR/Cas9 Base Editing Method for Improving Base Editing Efficiency in Streptomyces lividans 66, 1st Author, 2021
- Droplet-based microfluidic platform for high-throughput screening of Streptomyces, 2nd Author, 2021
- Regulatory Patterns of Crp on Monensin Biosynthesis in Streptomyces cinnamonensis, 2nd Author, 2020
- Discovery and Engineering of Cytochrome P450s for Terpenoid Biosynthesis, 2nd Author, 2019
- Characterization of three pathway-specific regulators for high production of monensin in Streptomyces cinnamonensis, 5th Author, 2017
- DasR positively controls monensin production at two-level regulation in Streptomyces cinnamonensis, 1st Author, 2016
- Preparation of Glycyrrhetinic Acid-modified PEG-PLGA Nanoparticles and the Affinity Evaluation on Hepatoma Cells, 4th Author, 2011
- 甘草次酸修饰海藻酸钠纳米给药系统的肝靶向性评估, 5th Author, 2011
