Areas of Focus
- 高通量筛选方法
- 红霉素生产
- CRISPR/Cas9技术
- 微流控平台
- 生物传感器
- 链霉菌遗传学
- 代谢工程
- 合成生物学
- 生物技术
- 工业微生物学
Work Experience
- 2021-06到现在 - 中国科学院天津工业生物技术研究所 - 副研究员
- 2017-07到2021-06 - 中国科学院天津工业生物技术研究所 - 助理研究员
- 2011-09到2017-06 - 天津大学 - 博士
- 2007-09到2011-06 - 南开大学 - 学士
Academic Background & Achievements
- 2011-09到2017-06 博士: 天津大学
- 2007-09到2011-06 学士: 南开大学
Publications
- CRISPR/Cas9-Mediated Multi-Locus Promoter Engineering in ery Cluster to Improve Erythromycin Production in Saccharopolyspora erythraea, 第11作者, 2023
- Product-driven high-throughput screening of industrial filamentous actinomycetes, 第11作者, 2023
- Modulating Sensitivity of an Erythromycin Biosensor for Precise High-Throughput Screening of Strains with Different Characteristics, 第11作者, 2023
- Repurposing conformational changes in ANL superfamily enzymes to rapidly generate biosensors for organic and amino acids, 第6作者, 2023
- Whole-cell biosensor and producer co-cultivation based microfludic platform for screening Saccharopolyspora erythraea with hyper erythromycin production, 第11作者, 2022
- Droplet-Microfluidic-Based Promoter Engineering and Expression Fine-Tuning for Improved Erythromycin Production in Saccharopolyspora erythraea NRRL 23338, 第2作者, 2022
- A CRISPR/dCas9-assisted system to clone toxic genes in Escherichia coli, 第2作者, 2021
- Antisense RNA Interference-Enhanced CRISPR/Cas9 Base Editing Method for Improving Base Editing Efficiency in Streptomyces lividans 66, 第1作者, 2021
- Droplet-based microfluidic platform for high-throughput screening of Streptomyces, 第2作者, 2021
- Regulatory Patterns of Crp on Monensin Biosynthesis in Streptomyces cinnamonensis, 第2作者, 2020
- Discovery and Engineering of Cytochrome P450s for Terpenoid Biosynthesis, 第2作者, 2019
- Characterization of three pathway-specific regulators for high production of monensin in Streptomyces cinnamonensis, 第5作者, 2017
- DasR positively controls monensin production at two-level regulation in Streptomyces cinnamonensis, 第1作者, 2016
- Preparation of Glycyrrhetinic Acid-modified PEG-PLGA Nanoparticles and the Affinity Evaluation on Hepatoma Cells, 第4作者, 2011
- 甘草次酸修饰海藻酸钠纳米给药系统的肝靶向性评估, 第5作者, 2011