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- Novel and potent inhibitors targeting DHODH are broad-spectrum antivirals against RNA viruses including newly-emerged coronavirus SARS-CoV-2 (vol 11, pg 723, 2020), Xiong, Rui, Zhang, Leike, Li, Shiliang, Sun, Yuan, Ding, Minyi, Wang, Yong, Zhao, Yongliang, Wu, Yan, Shang, Weijuan, Jiang, Xiaming, Shan, Jiwei, Shen, Zihao, Tong, Yi, Xu, Liuxin, Chen, Yu, Liu, Yingle, Zou, Gang, Lavillete, Dimitri, Zhao, Zhenjiang, Wang, Rui, Zhu, Lili, Xiao, Gengfu, Lan, Ke, Li, Honglin, Xu, Ke, 2022
- CoVac501, a self-adjuvanting peptide vaccine conjugated with TLR7 agonists, against SARS-CoV-2 induces protective immunity, Long, Yiru, Sun, Jianhua, Song, TianZhang, Liu, Tingting, Tang, Feng, Zhang, Xinxin, Ding, Longfei, Miao, Yunqiu, Zhu, Weiliang, Pan, Xiaoyan, An, Qi, Qin, Mian, Tong, Xiankun, Peng, Xionghua, Yu, Pan, Zhu, Peng, Xu, Jianqing, Zhang, Xiaoyan, Zhang, Yachun, Liu, Datao, Chen, Ben, Chen, Huilin, Zhang, Leike, Xiao, Gengfu, Zuo, Jianping, Tang, Wei, Zhou, Ji, Li, Heng, Xu, Zhijian, Zheng, HongYi, Long, XinYan, Qin, Qiuping, Gan, Yong, Ren, Jin, Huang, Wei, Zheng, YongTang, Jin, Guangyi, Gong, Likun, 2022
- A multi-targeting drug design strategy for identifying potent anti-SARS-CoV-2 inhibitors, Ren, Pengxuan, Shang, Weijuan, Yin, Wanchao, Ge, Huan, Wang, Lin, Zhang, Xianglei, Li, Bingqian, Li, Honglin, Xu, Yechun, Xu, Eric H, Jiang, Hualiang, Zhu, Lili, Zhang, Leike, Bai, Fang, 2022
- Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2, Dai, Wenhao, Jochmans, Dirk, Xie, Hang, Yang, Hang, Li, Jian, Su, Haixia, Chang, Di, Wang, Jiang, Peng, Jingjing, Zhu, Lili, Nian, Yong, Hilgenfeld, Rolf, Jiang, Hualiang, Chen, Kaixian, Zhang, Leike, Xu, Yechun, Neyts, Johan, Liu, Hong, 2022
- Oral remdesivir derivative VV116 is a potent inhibitor of respiratory syncytial virus with efficacy in mouse model, Zhang, Ruxue, Zhang, Yumin, Zheng, Wei, Shang, Weijuan, Wu, Yan, Li, Ning, Xiong, Jun, Jiang, Hualiang, Shen, Jingshan, Xiao, Gengfu, Xie, Yuanchao, Zhang, Leike, 2022
- Identification of pyrogallol as a warhead in design of covalent inhibitors for the SARS-CoV-2 3CL protease, Su, Haixia, Yao, Sheng, Zhao, Wenfeng, Zhang, Yumin, Liu, Jia, Shao, Qiang, Wang, Qingxing, Li, Minjun, Xie, Hang, Shang, Weijuan, Ke, Changqiang, Feng, Lu, Jiang, Xiangrui, Shen, Jingshan, Xiao, Gengfu, Jiang, Hualiang, Zhang, Leike, Ye, Yang, Xu, Yechun, 2021
- Design and development of an oral remdesivir derivative W116 against SARS-CoV-2, Yuanchao Xie, Wanchao Yin, Yumin Zhang, Weijuan Shang, Zhen Wang, Xiaodong Luan, Guanghui Tian, Haji AAisa, Yechun Xu, Gengfu Xiao, Jia Li, Hualiang Jiang, Shuyang Zhanq, Leike Zhang, HEric Xu, Jingshan Shen, 2021
- SARS-CoV-2 ORF9b inhibits RIG-I-MAVS antiviral signaling by interrupting K63-linked ubiquitination of NEMO, Wu, Jing, Shi, Yuheng, Pan, Xiaoyan, Wu, Shuang, Hou, Ruixia, Zhang, Yong, Zhong, Tiansheng, Tang, Hao, Du, Wei, Wang, Luying, Wo, Jing, Mu, Jingfang, Qiu, Yang, Yang, Ke, Zhang, LeiKe, Ye, BangCe, Qi, Nan, 2021
- High-Throughput Screening of an FDA-Approved Drug Library Identifies Inhibitors against Arenaviruses and SARS-CoV-2, Wan, Weiwei, Zhu, Shenglin, Li, Shufen, Shang, Weijuan, Zhang, Ruxue, Li, Hao, Liu, Wei, Xiao, Gengfu, Peng, Ke, Zhang, Leike, 2021
- Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2, Xie, Yuanchao, Yin, Wanchao, Zhang, Yumin, Shang, Weijuan, Wang, Zhen, Luan, Xiaodong, Tian, Guanghui, Aisa, Haji A, Xu, Yechun, Xiao, Gengfu, Li, Jia, Jiang, Hualiang, Zhang, Shuyang, Zhang, Leike, Xu, H Eric, Shen, Jingshan, 2021
- Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin, Yin, Wanchao, Luan, Xiaodong, Li, Zhihai, Zhou, Ziwei, Wang, Qingxing, Gao, Minqi, Wang, Xiaoxi, Zhou, Fulai, Shi, Jingjing, You, Erli, Liu, Mingliang, Wang, Qingxia, Jiang, Yi, Jiang, Hualiang, Xiao, Gengfu, Zhang, Leike, Yu, Xuekui, Zhang, Shuyang, Eric Xu, H, 2021
- Clinical effect and antiviral mechanism of T-705 in treating severe fever with thrombocytopenia syndrome, Li, Hao, Jiang, XiaMing, Cui, Ning, Yuan, Chun, Zhang, ShaoFei, Lu, QingBin, Yang, ZhenDong, Xin, QinLin, Song, YaBin, Zhang, XiaoAi, Liu, HaiZhou, Du, Juan, Fan, XueJuan, Yuan, Lan, Yuan, YiMei, Wang, Zhen, Wang, Juan, Zhang, Lan, Zhang, DongNa, Wang, ZhiBo, Dai, Ke, Bai, JieYing, Hao, ZhaoNian, Fan, Hang, Fang, LiQun, Xiao, Gengfu, Yang, Yang, Peng, Ke, Wang, HongQuan, Li, JianXiong, Zhang, LeiKe, Liu, Wei, 2021
- Calcium channel blocker amlodipine besylate therapy is associated with reduced case fatality rate of COVID-19 patients with hypertension (vol 6, 96, 2020), Zhang, LeiKe, Sun, Yuan, Zeng, Haolong, Wang, Qingxing, Jiang, Xiaming, Shang, WeiJuan, Wu, Yan, Li, Shufen, Zhang, YuLan, Hao, ZhaoNian, Chen, Hongbo, Jin, Runming, Liu, Wei, Li, Hao, Peng, Ke, Xiao, Gengfu, 2021
- High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors, Zhao, Yao, Du, Xiaoyu, Duan, Yinkai, Pan, Xiaoyan, Sun, Yifang, You, Tian, Han, Lin, Jin, Zhenming, Shang, Weijuan, Yu, Jing, Guo, Hangtian, Liu, Qianying, Wu, Yan, Peng, Chao, Wang, Jun, Zhu, Chenghao, Yang, Xiuna, Yang, Kailin, Lei, Ying, Guddat, Luke W, Xu, Wenqing, Xiao, Gengfu, Sun, Lei, Zhang, Leike, Rao, Zihe, Yang, Haitao, 2021
- Absorbed plant MIR2911 in honeysuckle decoction inhibits SARS-CoV-2 replication and accelerates the negative conversion of infected patients, Zhou, LiKun, Zhou, Zhen, Jiang, XiaMing, Zheng, Yishan, Chen, Xi, Fu, Zheng, Xiao, Gengfu, Zhang, ChenYu, Zhang, LeiKe, Yi, Yongxiang, 2020
- Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients, Su, Haixia, Yao, Sheng, Zhao, Wenfeng, Li, Minjun, Liu, Jia, Shang, Weijuan, Xie, Hang, Ke, Changqiang, Hu, Hangchen, Gao, Meina, Yu, Kunqian, Liu, Hong, Shen, Jingshan, Tang, Wei, Zhang, Leike, Xiao, Gengfu, Ni, Li, Wang, Daowen, Zuo, Jianping, Jiang, Hualiang, Bai, Fang, Wu, Yan, Ye, Yang, Xu, Yechun, 2020
- Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro, Manli Wang, Ruiyuan Cao, Leike Zhang, Xinglou Yang, Jia Liu, Mingyue Xu, Zhengli Shi, Zhihong Hu, Wu Zhong, Gengfu Xiao, 2020
- Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease, Dai, Wenhao, Zhang, Bing, Jiang, XiaMing, Su, Haixia, Li, Jian, Zhao, Yao, Xie, Xiong, Jin, Zhenming, Peng, Jingjing, Liu, Fengjiang, Li, Chunpu, Li, You, Bai, Fang, Wang, Haofeng, Cheng, Xi, Cen, Xiaobo, Hu, Shulei, Yang, Xiuna, Wang, Jiang, Liu, Xiang, Xiao, Gengfu, Jiang, Hualiang, Rao, Zihe, Zhang, LeiKe, Xu, Yechun, Yang, Haitao, Liu, Hong, 2020
- Decreased HD-MIR2911 absorption in human subjects with the SIDT1 polymorphism fails to inhibit SARS-CoV-2 replication, Zhou, Zhen, Zhou, Yu, Jiang, XiaMing, Wang, Yanbo, Chen, Xi, Xiao, Gengfu, Zhang, ChenYu, Yi, Yongxiang, Zhang, LeiKe, Li, Liang, 2020
- Structure of M-pro from SARS-CoV-2 and discovery of its inhibitors, Jin, Zhenming, Du, Xiaoyu, Xu, Yechun, Deng, Yongqiang, Liu, Meiqin, Zhao, Yao, Zhang, Bing, Li, Xiaofeng, Zhang, Leike, Peng, Chao, Duan, Yinkai, Yu, Jing, Wang, Lin, Yang, Kailin, Liu, Fengjiang, Jiang, Rendi, Yang, Xinglou, You, Tian, Liu, Xiaoce, Yang, Xiuna, Bai, Fang, Liu
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