Areas of Focus
- Flavivirus
- Enterovirus
- Antiviral Drugs
Work Experience
- 2012-05 - Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Associate Researcher
Academic Background & Achievements
- 2001-09 - PhD: Huazhong University of Science and Technology
- 1998-09 - Master's Degree: Huazhong University of Science and Technology
- 1994-09 - Bachelor's Degree: Shandong University
Publications
- A safe replication-defective Zika virus vaccine protects mice from viral infection and vertical transmission, ANTIVIRAL RESEARCH, 2023
- Attenuated WNV-poly(A) exerts a broad-spectrum oncolytic effect by selective virus replication and CD8+ T cell-dependent immune response, BIOMEDICINE & PHARMACOTHERAPY, 2023
- An alphavirus replicon particle delivering prefusion-stabilized spike protein provides potent immunoprotection against SARS-CoV-2 Omicron variant, SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022
- Berbamine hydrochloride potently inhibits SARS-CoV-2 infection by blocking S protein-mediated membrane fusion, PLOS NEGLECTED TROPICAL DISEASES, 2022
- High-Titer Self-Propagating Capsidless Chikungunya Virus Generated in Vero Cells as a Strategy for Alphavirus Vaccine Development, JOURNAL OF VIROLOGY, 2022
- A new screening system for entry inhibitors based on cell-to-cell transmitted syncytia formation mediated by self-propagating hybrid VEEV-SARS-CoV-2 replicon, EMERGING MICROBES & INFECTIONS, 2022
- Sequence duplication in 3 ' UTR modulates virus replication and virulence of Japanese encephalitis virus, EMERGING MICROBES & INFECTIONS, 2022
- In Vitro Inhibition of Alphaviruses by Lycorine, Virol Sin, 2021
- Increased morbidity of obese mice infected with mouse-adapted SARS-CoV-2, CELL DISCOVERY, 2021
- Rational design of West Nile virus vaccine through large replacement of 3 ' UTR with internal poly(A), EMBO MOLECULAR MEDICINE, 2021
Awards
- A replication-defective Zika virus vaccine protects mice from viral infection and vertical transmission (2023): Antiviral Research
- Attenuated WNV-poly(A) exerts a broad-spectrum oncolytic effect by selective virus replication and CD8+ T cell-dependent immune response (2023): Biomedicine & Pharmacotherapy