Professor | 叶寒青 | 数字化转型顾问

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Name	叶寒青
Contact Information	yehq@wh.iov.cn
Language ability	中文, 英语
Province	湖北

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Name

叶寒青

Contact Information

yehq@wh.iov.cn

Language ability

中文, 英语

Province

湖北

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2001-09 - 博士学位: 华中科技大学 1998-09 - 硕士学位: 华中科技大学 1994-09 - 本科学位: 山东大学
Work Experience	2012-05 - 现在 - 中国科学院武汉病毒研究所 - 副研究员
Awards	一种缺失衣壳蛋白基因的基孔肯雅病毒感染性克隆及构建方法和在制备减毒疫苗中的应用 (2019): 专利号: CN109536464A 一种带有绿色荧光蛋白基因的CA16感染性克隆及构建方法和应用 (2014): 专利号: CN103805634A

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2001-09 - 博士学位: 华中科技大学
1998-09 - 硕士学位: 华中科技大学
1994-09 - 本科学位: 山东大学

Work Experience

2012-05 - 现在 - 中国科学院武汉病毒研究所 - 副研究员

Awards

一种缺失衣壳蛋白基因的基孔肯雅病毒感染性克隆及构建方法和在制备减毒疫苗中的应用 (2019): 专利号: CN109536464A
一种带有绿色荧光蛋白基因的CA16感染性克隆及构建方法和应用 (2014): 专利号: CN103805634A

Areas of Focus	黄病毒肠道病毒抗病毒药物
Publications	一种缺失衣壳蛋白基因的基孔肯雅病毒感染性克隆及构建方法和在制备减毒疫苗中的应用, 专利号: CN109536464A, 2019 一种带有绿色荧光蛋白基因的CA16感染性克隆及构建方法和应用, 专利号: CN103805634A, 2014 一种带有荧光素酶基因的JEV感染性克隆及构建方法和应用, 专利号: CN103497972A, 2014 A safe replication-defective Zika virus vaccine protects mice from viral infection and vertical transmission, ANTIVIRAL RESEARCH, 2023 Attenuated WNV-poly(A) exerts a broad-spectrum oncolytic effect by selective virus replication and CD8+ T cell-dependent immune response, BIOMEDICINE & PHARMACOTHERAPY, 2023 An alphavirus replicon particle delivering prefusion-stabilized spike protein provides potent immunoprotection against SARS-CoV-2 Omicron variant, SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022 Berbamine hydrochloride potently inhibits SARS-CoV-2 infection by blocking S protein-mediated membrane fusion, PLOS NEGLECTED TROPICAL DISEASES, 2022 High-Titer Self-Propagating Capsidless Chikungunya Virus Generated in Vero Cells as a Strategy for Alphavirus Vaccine Development, JOURNAL OF VIROLOGY, 2022 A new screening system for entry inhibitors based on cell-to-cell transmitted syncytia formation mediated by self-propagating hybrid VEEV-SARS-CoV-2 replicon, EMERGING MICROBES & INFECTIONS, 2022 Sequence duplication in 3 ' UTR modulates virus replication and virulence of Japanese encephalitis virus, EMERGING MICROBES & INFECTIONS, 2022

Areas of Focus

黄病毒
肠道病毒
抗病毒药物

Publications

一种缺失衣壳蛋白基因的基孔肯雅病毒感染性克隆及构建方法和在制备减毒疫苗中的应用, 专利号: CN109536464A, 2019
一种带有绿色荧光蛋白基因的CA16感染性克隆及构建方法和应用, 专利号: CN103805634A, 2014
一种带有荧光素酶基因的JEV感染性克隆及构建方法和应用, 专利号: CN103497972A, 2014
A safe replication-defective Zika virus vaccine protects mice from viral infection and vertical transmission, ANTIVIRAL RESEARCH, 2023
Attenuated WNV-poly(A) exerts a broad-spectrum oncolytic effect by selective virus replication and CD8+ T cell-dependent immune response, BIOMEDICINE & PHARMACOTHERAPY, 2023
An alphavirus replicon particle delivering prefusion-stabilized spike protein provides potent immunoprotection against SARS-CoV-2 Omicron variant, SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022
Berbamine hydrochloride potently inhibits SARS-CoV-2 infection by blocking S protein-mediated membrane fusion, PLOS NEGLECTED TROPICAL DISEASES, 2022
High-Titer Self-Propagating Capsidless Chikungunya Virus Generated in Vero Cells as a Strategy for Alphavirus Vaccine Development, JOURNAL OF VIROLOGY, 2022
A new screening system for entry inhibitors based on cell-to-cell transmitted syncytia formation mediated by self-propagating hybrid VEEV-SARS-CoV-2 replicon, EMERGING MICROBES & INFECTIONS, 2022
Sequence duplication in 3 ' UTR modulates virus replication and virulence of Japanese encephalitis virus, EMERGING MICROBES & INFECTIONS, 2022

黄病毒肠道病毒抗病毒药物寨卡病毒 Sars-Cov-2 疫苗开发溶瘤效应病毒复制免疫反应分子设计

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