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叶寒青
Life Science
中国科学院大学
湖北
Language: 中文, 英语
黄病毒
肠道病毒
抗病毒药物
寨卡病毒
Sars-Cov-2
疫苗开发
溶瘤效应
病毒复制
免疫反应
分子设计
Areas of Focus
- 黄病毒
- 肠道病毒
- 抗病毒药物
Work Experience
- 2012-05 - 现在 - 中国科学院武汉病毒研究所 - 副研究员
Academic Background & Achievements
- 2001-09 - 博士学位: 华中科技大学
- 1998-09 - 硕士学位: 华中科技大学
- 1994-09 - 本科学位: 山东大学
Publications
- 一种缺失衣壳蛋白基因的基孔肯雅病毒感染性克隆及构建方法和在制备减毒疫苗中的应用, 专利号: CN109536464A, 2019
- 一种带有绿色荧光蛋白基因的CA16感染性克隆及构建方法和应用, 专利号: CN103805634A, 2014
- 一种带有荧光素酶基因的JEV感染性克隆及构建方法和应用, 专利号: CN103497972A, 2014
- A safe replication-defective Zika virus vaccine protects mice from viral infection and vertical transmission, ANTIVIRAL RESEARCH, 2023
- Attenuated WNV-poly(A) exerts a broad-spectrum oncolytic effect by selective virus replication and CD8+ T cell-dependent immune response, BIOMEDICINE & PHARMACOTHERAPY, 2023
- An alphavirus replicon particle delivering prefusion-stabilized spike protein provides potent immunoprotection against SARS-CoV-2 Omicron variant, SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022
- Berbamine hydrochloride potently inhibits SARS-CoV-2 infection by blocking S protein-mediated membrane fusion, PLOS NEGLECTED TROPICAL DISEASES, 2022
- High-Titer Self-Propagating Capsidless Chikungunya Virus Generated in Vero Cells as a Strategy for Alphavirus Vaccine Development, JOURNAL OF VIROLOGY, 2022
- A new screening system for entry inhibitors based on cell-to-cell transmitted syncytia formation mediated by self-propagating hybrid VEEV-SARS-CoV-2 replicon, EMERGING MICROBES & INFECTIONS, 2022
- Sequence duplication in 3 ' UTR modulates virus replication and virulence of Japanese encephalitis virus, EMERGING MICROBES & INFECTIONS, 2022
Awards
- 一种缺失衣壳蛋白基因的基孔肯雅病毒感染性克隆及构建方法和在制备减毒疫苗中的应用 (2019): 专利号: CN109536464A
- 一种带有绿色荧光蛋白基因的CA16感染性克隆及构建方法和应用 (2014): 专利号: CN103805634A
