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Liguo Zhang
Life Science
University of Chinese Academy of Sciences
Beijing
Language: English, Chinese
Hiv
Infection
Pathogenesis
Immune Response
Cd4+ T Cells
Dendritic Cells
Humanized Mouse Models
Virology
Immunology
Chronic Infection
Areas of Focus
- Mechanisms of HIV infection and pathogenesis
Work Experience
- 2008-10 to Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
- 2000-09 to 2002-07 - Institute of Virology, Chinese Academy of Preventive Medicine - Assistant Researcher
Academic Background & Achievements
- 2004-11 to 2008-09 Postdoctoral: University of North Carolina at Chapel Hill
- 2002-07 to 2004-10 Postdoctoral: Yale University
- 1997-09 to 2000-07 Ph.D.: Institute of Virology, Chinese Academy of Preventive Medicine
- 1994-09 to 1997-07 Master's: Nanjing Agricultural University
- 1990-09 to 1994-07 Bachelor's: Hebei Agricultural University
Publications
- Type 1 interferon contributes to CD4+ T cell depletion in HIV-1 induced human thymus., Journal of Virology, 2011
- Preferential depletion of CD2low plasmacytoid dendritic cells in HIV-infected subjects., Cellular and Molecular Immunology, 2011
- A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease., Gastroenterology, 2011
- Efficient infection, activation, and impairment of pDCs in the BM and peripheral lymphoid organs during early HIV-1 infection in humanized rag2-/-gammaC-/- mice in vivo., Blood, 2011
- Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis., Sci China Life Sci, 2010
- Evolution of the HIV-1 env gene in the Rag2-/-gammaC-/- humanized mouse model., Journal of Virology, 2010
- The heptad repeat 2 domain is a major determinant for enhanced human immunodeficiency virus type 1 (HIV-1) fusion and pathogenicity of a highly pathogenic HIV-1 Env., Journal of Virology, 2009
