Professor | Liguo Zhang | Asia Growth Partners

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Name

Liguo Zhang

Contact Information

liguozhang@sun5.ibp.ac.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2004-11 to 2008-09 Postdoctoral: University of North Carolina at Chapel Hill 2002-07 to 2004-10 Postdoctoral: Yale University 1997-09 to 2000-07 Ph.D.: Institute of Virology, Chinese Academy of Preventive Medicine 1994-09 to 1997-07 Master's: Nanjing Agricultural University 1990-09 to 1994-07 Bachelor's: Hebei Agricultural University
Work Experience	2008-10 to Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher 2000-09 to 2002-07 - Institute of Virology, Chinese Academy of Preventive Medicine - Assistant Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2004-11 to 2008-09 Postdoctoral: University of North Carolina at Chapel Hill
2002-07 to 2004-10 Postdoctoral: Yale University
1997-09 to 2000-07 Ph.D.: Institute of Virology, Chinese Academy of Preventive Medicine
1994-09 to 1997-07 Master's: Nanjing Agricultural University
1990-09 to 1994-07 Bachelor's: Hebei Agricultural University

Work Experience

2008-10 to Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
2000-09 to 2002-07 - Institute of Virology, Chinese Academy of Preventive Medicine - Assistant Researcher

Areas of Focus	Mechanisms of HIV infection and pathogenesis
Publications	Type 1 interferon contributes to CD4+ T cell depletion in HIV-1 induced human thymus., Journal of Virology, 2011 Preferential depletion of CD2low plasmacytoid dendritic cells in HIV-infected subjects., Cellular and Molecular Immunology, 2011 A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease., Gastroenterology, 2011 Efficient infection, activation, and impairment of pDCs in the BM and peripheral lymphoid organs during early HIV-1 infection in humanized rag2-/-gammaC-/- mice in vivo., Blood, 2011 Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis., Sci China Life Sci, 2010 Evolution of the HIV-1 env gene in the Rag2-/-gammaC-/- humanized mouse model., Journal of Virology, 2010 The heptad repeat 2 domain is a major determinant for enhanced human immunodeficiency virus type 1 (HIV-1) fusion and pathogenicity of a highly pathogenic HIV-1 Env., Journal of Virology, 2009

Areas of Focus

Mechanisms of HIV infection and pathogenesis

Publications

Type 1 interferon contributes to CD4+ T cell depletion in HIV-1 induced human thymus., Journal of Virology, 2011
Preferential depletion of CD2low plasmacytoid dendritic cells in HIV-infected subjects., Cellular and Molecular Immunology, 2011
A humanized mouse model to study hepatitis C virus infection, immune response, and liver disease., Gastroenterology, 2011
Efficient infection, activation, and impairment of pDCs in the BM and peripheral lymphoid organs during early HIV-1 infection in humanized rag2-/-gammaC-/- mice in vivo., Blood, 2011
Current humanized mouse models for studying human immunology and HIV-1 immuno-pathogenesis., Sci China Life Sci, 2010
Evolution of the HIV-1 env gene in the Rag2-/-gammaC-/- humanized mouse model., Journal of Virology, 2010
The heptad repeat 2 domain is a major determinant for enhanced human immunodeficiency virus type 1 (HIV-1) fusion and pathogenicity of a highly pathogenic HIV-1 Env., Journal of Virology, 2009

Hiv Infection Pathogenesis Immune Response Cd4+ T Cells Dendritic Cells Humanized Mouse Models Virology Immunology Chronic Infection

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