Professor | Kun Chen | Asia Growth Partners

Name	Kun Chen
Contact Information	chenk@tongji.edu.cn
Language ability	Chinese, English
Province	Shanghai

Name

Kun Chen

Contact Information

chenk@tongji.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2009 - Bachelor's Degree: Beijing Normal University 2012 - Master's Degree in Cell Biology: Beijing Normal University 2017 - PhD in Immunology: Zhejiang University Published in journals like Cell, Science Advances, and Journal of Clinical Investigation Holds two national invention patents Selected for multiple young talent programs in China
Work Experience	2017-08 to 2020-08 - Postdoctoral Researcher at Peking Union Medical College, Chinese Academy of Medical Sciences 2020-11 to present - Faculty at Tongji University, School of Life Sciences and Technology
Awards	2020: Selected for the Young Talent Support Project by the China Association for Science and Technology 2021: Selected for the Shanghai Young Science and Technology Star Project 2022: Nominated for the Shanghai 'Top 35 Youth in Science and Technology' Plan

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2009 - Bachelor's Degree: Beijing Normal University
2012 - Master's Degree in Cell Biology: Beijing Normal University
2017 - PhD in Immunology: Zhejiang University
Published in journals like Cell, Science Advances, and Journal of Clinical Investigation
Holds two national invention patents
Selected for multiple young talent programs in China

Work Experience

2017-08 to 2020-08 - Postdoctoral Researcher at Peking Union Medical College, Chinese Academy of Medical Sciences
2020-11 to present - Faculty at Tongji University, School of Life Sciences and Technology

Awards

2020: Selected for the Young Talent Support Project by the China Association for Science and Technology
2021: Selected for the Shanghai Young Science and Technology Star Project
2022: Nominated for the Shanghai 'Top 35 Youth in Science and Technology' Plan

Areas of Focus	Infection immunity and inflammation Epigenetic and metabolic regulation
Publications	Cytotoxic CD161-CD8+ TEMRA cells contribute to the pathogenesis of systemic lupus erythematosus, Chen K, 2023 Methyltransferase SETD2-mediated methylation of STAT1 is critical for interferon antiviral activity, Chen K, 2017 lncRNA-GM targets Foxo1 to promote T cell–mediated autoimmunity, Chen K, 2022 Gasdermin D inhibition confers antineutrophil mediated cardioprotection in acute myocardial infarction, Chen K, 2022 cGAS-STING pathway in senescence-related inflammation, Chen K, 2018 RNA-binding protein ZCCHC4 promotes human cancer chemoresistance by disrupting DNA-damage-induced apoptosis, Chen K, 2022 Regulation of type I interferon signaling in immunity and inflammation: a comprehensive review, Chen K, 2017 CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis, Chen K, 2019 Methyltransferase Ash1l controls T cell autoimmunity by iTreg cell polarization via suppression of lncRNA lnc-Smad3, Chen K, 2017 Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO, Chen K, 2014

Areas of Focus

Infection immunity and inflammation
Epigenetic and metabolic regulation

Publications

Cytotoxic CD161-CD8+ TEMRA cells contribute to the pathogenesis of systemic lupus erythematosus, Chen K, 2023
Methyltransferase SETD2-mediated methylation of STAT1 is critical for interferon antiviral activity, Chen K, 2017
lncRNA-GM targets Foxo1 to promote T cell–mediated autoimmunity, Chen K, 2022
Gasdermin D inhibition confers antineutrophil mediated cardioprotection in acute myocardial infarction, Chen K, 2022
cGAS-STING pathway in senescence-related inflammation, Chen K, 2018
RNA-binding protein ZCCHC4 promotes human cancer chemoresistance by disrupting DNA-damage-induced apoptosis, Chen K, 2022
Regulation of type I interferon signaling in immunity and inflammation: a comprehensive review, Chen K, 2017
CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis, Chen K, 2019
Methyltransferase Ash1l controls T cell autoimmunity by iTreg cell polarization via suppression of lncRNA lnc-Smad3, Chen K, 2017
Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO, Chen K, 2014

Immunity Inflammation Epigenetics Metabolism Cross-Regulation Molecular Mechanisms Chronic Diseases Immune Therapy Stem Cell Therapy Clinical Translation

Dianjianyi Sun - Peking University

Kun Chen - Tongji University

Qiwei Zhai - University of Chinese Academy of Sciences

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