Professor | Kun Chen | Asia Growth Partners

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Name	Kun Chen
Contact Information	chenk@tongji.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Kun Chen

Contact Information

chenk@tongji.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Tongji University
Faculty	Life Sciences
Academic Background & Achievements	2009 - Bachelor's Degree: Beijing Normal University 2012 - Master's Degree in Cell Biology: Beijing Normal University 2017 - PhD in Immunology: Zhejiang University Published in journals like Cell, Science Advances, and Journal of Clinical Investigation Holds two national invention patents
Work Experience	2017-08 to 2020-08 - Postdoctoral Researcher at Peking Union Medical College, Chinese Academy of Medical Sciences 2020-11 to present - Faculty at School of Life Sciences and Technology, Tongji University
Awards	2020: Selected for the China Association for Science and Technology Youth Talent Lift Project 2021: Selected for the Shanghai Youth Science and Technology Star Project 2022: Nominated for the Shanghai 'Top 35 Youth in Science and Technology' Plan

University/Lab Affiliation and Title

Tongji University

Faculty

Life Sciences

Academic Background & Achievements

2009 - Bachelor's Degree: Beijing Normal University
2012 - Master's Degree in Cell Biology: Beijing Normal University
2017 - PhD in Immunology: Zhejiang University
Published in journals like Cell, Science Advances, and Journal of Clinical Investigation
Holds two national invention patents

Work Experience

2017-08 to 2020-08 - Postdoctoral Researcher at Peking Union Medical College, Chinese Academy of Medical Sciences
2020-11 to present - Faculty at School of Life Sciences and Technology, Tongji University

Awards

2020: Selected for the China Association for Science and Technology Youth Talent Lift Project
2021: Selected for the Shanghai Youth Science and Technology Star Project
2022: Nominated for the Shanghai 'Top 35 Youth in Science and Technology' Plan

Areas of Focus	Infection immunity and inflammation Epigenetic and metabolic regulation
Publications	Cytotoxic CD161-CD8+ TEMRA cells contribute to the pathogenesis of systemic lupus erythematosus, Xiong H, Cui M, Kong N, Jing J, Xu Y, Liu X, Yang F, Xu Z, Yan Y, Zhao D, Zou Z, Xia M, Cen J, Tan G, Huai C, Fu Q, Guo Q, Chen K, 2023 Methyltransferase SETD2-mediated methylation of STAT1 is critical for interferon antiviral activity, Chen K, Liu J, Liu S, Xia M, Zhang X, Han D, Jiang Y, Wang C, Cao X, 2017 lncRNA-GM targets Foxo1 to promote T cell–mediated autoimmunity, Chen Y, Liu J, Zhang X, hu H, Wang Y, Li Z, Liu Y, Liu S, Liu S, Li N, Chen K, Cao X, 2022 Gasdermin D inhibition confers antineutrophil mediated cardioprotection in acute myocardial infarction, Jiang K, Tu Z, Chen K, Xu Y, Chen F, Xu S, Shi T, Qian J, Shen L, Hwa J, Wang D, Xiang Y, 2022 cGAS-STING pathway in senescence-related inflammation, Chen K, Liu J, Cao X, 2018 RNA-binding protein ZCCHC4 promotes human cancer chemoresistance by disrupting DNA-damage-induced apoptosis, Zhu H, Chen K, Chen Y, Liu J, Zhang X, Zhou, Y Liu Q, Wang B, Chen T, Cao X, 2022 Regulation of type I interferon signaling in immunity and inflammation:a comprehensive review, Chen K, Liu J, Cao X, 2017 CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis, Liu J, Zhang X, Chen K, Cheng Y, Liu S, Xia M, Chen Y, Zhu H, Li Z, Cao X, 2019 Methyltransferase Ash1l controls T cell autoimmunity by iTreg cell polarization via suppression of lncRNA lnc-Smad3, Xia M, Liu J, Liu S, Chen K, Lin H, Jiang M, Xu X, Xue Y, Liu W, Gu Y, 2017 Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO, Liu J, Han C, Xie B, Wu Y, Liu S, Chen K, Xia M, Zhang Y, Song L, Li Z, 2014

Areas of Focus

Infection immunity and inflammation
Epigenetic and metabolic regulation

Publications

Cytotoxic CD161-CD8+ TEMRA cells contribute to the pathogenesis of systemic lupus erythematosus, Xiong H, Cui M, Kong N, Jing J, Xu Y, Liu X, Yang F, Xu Z, Yan Y, Zhao D, Zou Z, Xia M, Cen J, Tan G, Huai C, Fu Q, Guo Q, Chen K, 2023
Methyltransferase SETD2-mediated methylation of STAT1 is critical for interferon antiviral activity, Chen K, Liu J, Liu S, Xia M, Zhang X, Han D, Jiang Y, Wang C, Cao X, 2017
lncRNA-GM targets Foxo1 to promote T cell–mediated autoimmunity, Chen Y, Liu J, Zhang X, hu H, Wang Y, Li Z, Liu Y, Liu S, Liu S, Li N, Chen K, Cao X, 2022
Gasdermin D inhibition confers antineutrophil mediated cardioprotection in acute myocardial infarction, Jiang K, Tu Z, Chen K, Xu Y, Chen F, Xu S, Shi T, Qian J, Shen L, Hwa J, Wang D, Xiang Y, 2022
cGAS-STING pathway in senescence-related inflammation, Chen K, Liu J, Cao X, 2018
RNA-binding protein ZCCHC4 promotes human cancer chemoresistance by disrupting DNA-damage-induced apoptosis, Zhu H, Chen K, Chen Y, Liu J, Zhang X, Zhou, Y Liu Q, Wang B, Chen T, Cao X, 2022
Regulation of type I interferon signaling in immunity and inflammation:a comprehensive review, Chen K, Liu J, Cao X, 2017
CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis, Liu J, Zhang X, Chen K, Cheng Y, Liu S, Xia M, Chen Y, Zhu H, Li Z, Cao X, 2019
Methyltransferase Ash1l controls T cell autoimmunity by iTreg cell polarization via suppression of lncRNA lnc-Smad3, Xia M, Liu J, Liu S, Chen K, Lin H, Jiang M, Xu X, Xue Y, Liu W, Gu Y, 2017
Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO, Liu J, Han C, Xie B, Wu Y, Liu S, Chen K, Xia M, Zhang Y, Song L, Li Z, 2014

Immunity Inflammation Epigenetics Metabolism Cross-Regulation Molecular Mechanisms Chronic Diseases Immune Therapy Stem Cell Therapy Clinical Translation

Kun Chen - Tongji University

Dianjianyi Sun - Peking University

Qiwei Zhai - University of Chinese Academy of Sciences

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