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Yan Zhao
Life Science
University of Chinese Academy of Sciences
Beijing
Language: Chinese, English
Membrane Proteins
Structure
Function
Biophysics
Cryo-Em
Protein Complexes
Ion Channels
Transport Mechanisms
Synaptic Transmission
Molecular Biology
Areas of Focus
- Structure and Function of Membrane Proteins
Work Experience
- 2020-01 to Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher, Group Leader
- 2015-07 to 2019-12 - Oregon Health & Science University/Howard Hughes Medical Institute - Postdoctoral Researcher
- 2010-09 to 2015-07 - University of Science and Technology of China & Institute of Biophysics, Chinese Academy of Sciences - PhD Student
- 2006-09 to 2010-07 - Texas College, Department of Physics - Bachelor's Student
Academic Background & Achievements
- 2010-09 to 2015-07 PhD: University of Science and Technology of China & Institute of Biophysics, Chinese Academy of Sciences
- 2006-09 to 2010-07 Bachelor's Degree: Texas College, Department of Physics
Publications
- Structural basis for modulation of human Na(V)1.3 by clinical drug and selective antagonist, 12th Author, Corresponding Author, 2022
- TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells, 6th Author, 2021
- Closed-state inactivation and pore-blocker modulation mechanisms of human Ca(V)2.2, 13th Author, Corresponding Author, 2021
- Kainate receptor modulation by NETO2, 13th Author, Corresponding Author, 2021
- Structure of human glycosylphosphatidylinositol transamidase, 1st Author, Corresponding Author, 2021
- Structure and mechanism of the human NHE1-CHP1 complex, 9th Author, Corresponding Author, 2021
- Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM, 1st Author, 2019
- Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion, 2nd Author, 2018
- Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion, 1st Author, 2018
- Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM, 2nd Author, 2017
- Thermodynamics of ABC transporters, 3rd Author, 2016
- Crystal structure of E. coli lipoprotein diacylglyceryl transferase, 2nd Author, 2016
- Architecture of fully occupied GluA2 AMPA receptor – TARP complex elucidated by cryo-EM, 1st Author, 2016
- Proton transfer-mediated GPCR activation, 4th Author, 2015
- Substrate-bound structure of the E. coli multidrug resistance transporter MdfA., 2nd Author, 2015
- Energy coupling mechanisms of MFS transporters, 2nd Author, 2015
- How does transmembrane electrochemical potential drive the rotation of Fo motor in an ATP synthase?, 3rd Author, 2015
- Proton transfer-mediated GPCR activation, 4th Author, 2015
- Crystal structure and biochemical studies of Brucella melitensis 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase, 2nd Author, 2014
- Structural basis for lipopolysaccharide insertion in the bacterial outer membrane, 3rd Author, 2014
- Crystal Structure of the E.coli Peptide Transporter YbgH, 1st Author, 2014
- Structure of the nonameric bacterial amyloid secretion channel, 2nd Author, 2014
- Crystal structure of lipid phosphatase Escherichia coli phosphatidylglycerophosphate phosphatase B., 3rd Author, 2014
- Atomic resolution structure of the E. coli YajR transporter YAM domain, 2nd Author, 2014
- Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A, 2nd Author, 2013
- Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum, 4th Author, 2012
- Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum, 4th Author, 2012
