Professor | Yan Zhao | Asia Growth Partners

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Name	Yan Zhao
Contact Information	zhaoy@ibp.ac.cn
Language ability	Chinese, English
Province	Beijing

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Name

Yan Zhao

Contact Information

zhaoy@ibp.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2010-09 to 2015-07 PhD: University of Science and Technology of China & Institute of Biophysics, Chinese Academy of Sciences 2006-09 to 2010-07 Bachelor's Degree: Texas College, Department of Physics
Work Experience	2020-01 to Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher, Group Leader 2015-07 to 2019-12 - Oregon Health & Science University/Howard Hughes Medical Institute - Postdoctoral Researcher 2010-09 to 2015-07 - University of Science and Technology of China & Institute of Biophysics, Chinese Academy of Sciences - PhD Student 2006-09 to 2010-07 - Texas College, Department of Physics - Bachelor's Student

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2010-09 to 2015-07 PhD: University of Science and Technology of China & Institute of Biophysics, Chinese Academy of Sciences
2006-09 to 2010-07 Bachelor's Degree: Texas College, Department of Physics

Work Experience

2020-01 to Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher, Group Leader
2015-07 to 2019-12 - Oregon Health & Science University/Howard Hughes Medical Institute - Postdoctoral Researcher
2010-09 to 2015-07 - University of Science and Technology of China & Institute of Biophysics, Chinese Academy of Sciences - PhD Student
2006-09 to 2010-07 - Texas College, Department of Physics - Bachelor's Student

Areas of Focus	Structure and Function of Membrane Proteins
Publications	Structural basis for modulation of human Na(V)1.3 by clinical drug and selective antagonist, 12th Author, Corresponding Author, 2022 TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells, 6th Author, 2021 Closed-state inactivation and pore-blocker modulation mechanisms of human Ca(V)2.2, 13th Author, Corresponding Author, 2021 Kainate receptor modulation by NETO2, 13th Author, Corresponding Author, 2021 Structure of human glycosylphosphatidylinositol transamidase, 1st Author, Corresponding Author, 2021 Structure and mechanism of the human NHE1-CHP1 complex, 9th Author, Corresponding Author, 2021 Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM, 1st Author, 2019 Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion, 2nd Author, 2018 Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion, 1st Author, 2018 Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM, 2nd Author, 2017 Thermodynamics of ABC transporters, 3rd Author, 2016 Crystal structure of E. coli lipoprotein diacylglyceryl transferase, 2nd Author, 2016 Architecture of fully occupied GluA2 AMPA receptor – TARP complex elucidated by cryo-EM, 1st Author, 2016 Proton transfer-mediated GPCR activation, 4th Author, 2015 Substrate-bound structure of the E. coli multidrug resistance transporter MdfA., 2nd Author, 2015 Energy coupling mechanisms of MFS transporters, 2nd Author, 2015 How does transmembrane electrochemical potential drive the rotation of Fo motor in an ATP synthase?, 3rd Author, 2015 Proton transfer-mediated GPCR activation, 4th Author, 2015 Crystal structure and biochemical studies of Brucella melitensis 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase, 2nd Author, 2014 Structural basis for lipopolysaccharide insertion in the bacterial outer membrane, 3rd Author, 2014 Crystal Structure of the E.coli Peptide Transporter YbgH, 1st Author, 2014 Structure of the nonameric bacterial amyloid secretion channel, 2nd Author, 2014 Crystal structure of lipid phosphatase Escherichia coli phosphatidylglycerophosphate phosphatase B., 3rd Author, 2014 Atomic resolution structure of the E. coli YajR transporter YAM domain, 2nd Author, 2014 Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A, 2nd Author, 2013 Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum, 4th Author, 2012 Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum, 4th Author, 2012

Areas of Focus

Structure and Function of Membrane Proteins

Publications

Structural basis for modulation of human Na(V)1.3 by clinical drug and selective antagonist, 12th Author, Corresponding Author, 2022
TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells, 6th Author, 2021
Closed-state inactivation and pore-blocker modulation mechanisms of human Ca(V)2.2, 13th Author, Corresponding Author, 2021
Kainate receptor modulation by NETO2, 13th Author, Corresponding Author, 2021
Structure of human glycosylphosphatidylinositol transamidase, 1st Author, Corresponding Author, 2021
Structure and mechanism of the human NHE1-CHP1 complex, 9th Author, Corresponding Author, 2021
Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM, 1st Author, 2019
Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion, 2nd Author, 2018
Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion, 1st Author, 2018
Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM, 2nd Author, 2017
Thermodynamics of ABC transporters, 3rd Author, 2016
Crystal structure of E. coli lipoprotein diacylglyceryl transferase, 2nd Author, 2016
Architecture of fully occupied GluA2 AMPA receptor – TARP complex elucidated by cryo-EM, 1st Author, 2016
Proton transfer-mediated GPCR activation, 4th Author, 2015
Substrate-bound structure of the E. coli multidrug resistance transporter MdfA., 2nd Author, 2015
Energy coupling mechanisms of MFS transporters, 2nd Author, 2015
How does transmembrane electrochemical potential drive the rotation of Fo motor in an ATP synthase?, 3rd Author, 2015
Proton transfer-mediated GPCR activation, 4th Author, 2015
Crystal structure and biochemical studies of Brucella melitensis 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase, 2nd Author, 2014
Structural basis for lipopolysaccharide insertion in the bacterial outer membrane, 3rd Author, 2014
Crystal Structure of the E.coli Peptide Transporter YbgH, 1st Author, 2014
Structure of the nonameric bacterial amyloid secretion channel, 2nd Author, 2014
Crystal structure of lipid phosphatase Escherichia coli phosphatidylglycerophosphate phosphatase B., 3rd Author, 2014
Atomic resolution structure of the E. coli YajR transporter YAM domain, 2nd Author, 2014
Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A, 2nd Author, 2013
Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum, 4th Author, 2012
Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum, 4th Author, 2012

Membrane Proteins Structure Function Biophysics Cryo-Em Protein Complexes Ion Channels Transport Mechanisms Synaptic Transmission Molecular Biology

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