Areas of Focus
- 膜蛋白的结构与功能研究
Work Experience
- 2020-01至今 - 中国科学院生物物理研究所 - 研究员、课题组长
- 2015-07至2019-12 - 美国俄勒冈健康与科学大学/霍华德·休斯医学研究所 - 博士后
- 2010-09至2015-07 - 中国科学技术大学 & 中科院生物物理所 - 博士生
- 2006-09至2010-07 - 德州学院物理系 - 学士生
Academic Background & Achievements
- 2010-09至2015-07 博士学位: 中国科学技术大学 & 中科院生物物理所
- 2006-09至2010-07 学士学位: 德州学院物理系
Publications
- Structural basis for modulation of human Na(V)1.3 by clinical drug and selective antagonist, 第12作者,通讯作者, 2022
- TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells, 第6作者, 2021
- Closed-state inactivation and pore-blocker modulation mechanisms of human Ca(V)2.2, 第13作者,通讯作者, 2021
- Kainate receptor modulation by NETO2, 第13作者,通讯作者, 2021
- Structure of human glycosylphosphatidylinositol transamidase, 第1作者,通讯作者, 2021
- Structure and mechanism of the human NHE1-CHP1 complex, 第9作者,通讯作者, 2021
- Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM, 第1作者, 2019
- Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion, 第2作者, 2018
- Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion, 第1作者, 2018
- Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM, 第2作者, 2017
- Thermodynamics of ABC transporters, 第3作者, 2016
- Crystal structure of E. coli lipoprotein diacylglyceryl transferase, 第2作者, 2016
- Architecture of fully occupied GluA2 AMPA receptor – TARP complex elucidated by cryo-EM, 第1作者, 2016
- Proton transfer-mediated GPCR activation, 第4作者, 2015
- Substrate-bound structure of the E. coli multidrug resistance transporter MdfA., 第2作者, 2015
- Energy coupling mechanisms of MFS transporters, 第2作者, 2015
- How does transmembrane electrochemical potential drive the rotation of Fo motor in an ATP synthase?, 第3作者, 2015
- Proton transfer-mediated GPCR activation, 第4作者, 2015
- Crystal structure and biochemical studies of Brucella melitensis 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase, 第2作者, 2014
- Structural basis for lipopolysaccharide insertion in the bacterial outer membrane, 第3作者, 2014
- Crystal Structure of the E.coli Peptide Transporter YbgH, 第1作者, 2014
- Structure of the nonameric bacterial amyloid secretion channel, 第2作者, 2014
- Crystal structure of lipid phosphatase Escherichia coli phosphatidylglycerophosphate phosphatase B., 第3作者, 2014
- Atomic resolution structure of the E. coli YajR transporter YAM domain, 第2作者, 2014
- Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A, 第2作者, 2013
- Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum, 第4作者, 2012
- Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum, 第4作者, 2012