Professor | 赵岩 | 数字化转型顾问

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Name	赵岩
Contact Information	zhaoy@ibp.ac.cn
Language ability	中文, 英语
Province	北京

Upload Avatar (500 x 500)

Name

赵岩

Contact Information

zhaoy@ibp.ac.cn

Language ability

中文, 英语

Province

北京

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2010-09至2015-07 博士学位: 中国科学技术大学 & 中科院生物物理所 2006-09至2010-07 学士学位: 德州学院物理系
Work Experience	2020-01至今 - 中国科学院生物物理研究所 - 研究员、课题组长 2015-07至2019-12 - 美国俄勒冈健康与科学大学/霍华德·休斯医学研究所 - 博士后 2010-09至2015-07 - 中国科学技术大学 & 中科院生物物理所 - 博士生 2006-09至2010-07 - 德州学院物理系 - 学士生

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2010-09至2015-07 博士学位: 中国科学技术大学 & 中科院生物物理所
2006-09至2010-07 学士学位: 德州学院物理系

Work Experience

2020-01至今 - 中国科学院生物物理研究所 - 研究员、课题组长
2015-07至2019-12 - 美国俄勒冈健康与科学大学/霍华德·休斯医学研究所 - 博士后
2010-09至2015-07 - 中国科学技术大学 & 中科院生物物理所 - 博士生
2006-09至2010-07 - 德州学院物理系 - 学士生

Areas of Focus	膜蛋白的结构与功能研究
Publications	Structural basis for modulation of human Na(V)1.3 by clinical drug and selective antagonist, 第12作者，通讯作者, 2022 TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells, 第6作者, 2021 Closed-state inactivation and pore-blocker modulation mechanisms of human Ca(V)2.2, 第13作者，通讯作者, 2021 Kainate receptor modulation by NETO2, 第13作者，通讯作者, 2021 Structure of human glycosylphosphatidylinositol transamidase, 第1作者，通讯作者, 2021 Structure and mechanism of the human NHE1-CHP1 complex, 第9作者，通讯作者, 2021 Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM, 第1作者, 2019 Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion, 第2作者, 2018 Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion, 第1作者, 2018 Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM, 第2作者, 2017 Thermodynamics of ABC transporters, 第3作者, 2016 Crystal structure of E. coli lipoprotein diacylglyceryl transferase, 第2作者, 2016 Architecture of fully occupied GluA2 AMPA receptor – TARP complex elucidated by cryo-EM, 第1作者, 2016 Proton transfer-mediated GPCR activation, 第4作者, 2015 Substrate-bound structure of the E. coli multidrug resistance transporter MdfA., 第2作者, 2015 Energy coupling mechanisms of MFS transporters, 第2作者, 2015 How does transmembrane electrochemical potential drive the rotation of Fo motor in an ATP synthase?, 第3作者, 2015 Proton transfer-mediated GPCR activation, 第4作者, 2015 Crystal structure and biochemical studies of Brucella melitensis 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase, 第2作者, 2014 Structural basis for lipopolysaccharide insertion in the bacterial outer membrane, 第3作者, 2014 Crystal Structure of the E.coli Peptide Transporter YbgH, 第1作者, 2014 Structure of the nonameric bacterial amyloid secretion channel, 第2作者, 2014 Crystal structure of lipid phosphatase Escherichia coli phosphatidylglycerophosphate phosphatase B., 第3作者, 2014 Atomic resolution structure of the E. coli YajR transporter YAM domain, 第2作者, 2014 Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A, 第2作者, 2013 Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum, 第4作者, 2012 Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum, 第4作者, 2012

Areas of Focus

膜蛋白的结构与功能研究

Publications

Structural basis for modulation of human Na(V)1.3 by clinical drug and selective antagonist, 第12作者，通讯作者, 2022
TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells, 第6作者, 2021
Closed-state inactivation and pore-blocker modulation mechanisms of human Ca(V)2.2, 第13作者，通讯作者, 2021
Kainate receptor modulation by NETO2, 第13作者，通讯作者, 2021
Structure of human glycosylphosphatidylinositol transamidase, 第1作者，通讯作者, 2021
Structure and mechanism of the human NHE1-CHP1 complex, 第9作者，通讯作者, 2021
Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM, 第1作者, 2019
Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion, 第2作者, 2018
Structure of YidC from Thermotoga maritima and its implications for YidC-mediated membrane protein insertion, 第1作者, 2018
Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM, 第2作者, 2017
Thermodynamics of ABC transporters, 第3作者, 2016
Crystal structure of E. coli lipoprotein diacylglyceryl transferase, 第2作者, 2016
Architecture of fully occupied GluA2 AMPA receptor – TARP complex elucidated by cryo-EM, 第1作者, 2016
Proton transfer-mediated GPCR activation, 第4作者, 2015
Substrate-bound structure of the E. coli multidrug resistance transporter MdfA., 第2作者, 2015
Energy coupling mechanisms of MFS transporters, 第2作者, 2015
How does transmembrane electrochemical potential drive the rotation of Fo motor in an ATP synthase?, 第3作者, 2015
Proton transfer-mediated GPCR activation, 第4作者, 2015
Crystal structure and biochemical studies of Brucella melitensis 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase, 第2作者, 2014
Structural basis for lipopolysaccharide insertion in the bacterial outer membrane, 第3作者, 2014
Crystal Structure of the E.coli Peptide Transporter YbgH, 第1作者, 2014
Structure of the nonameric bacterial amyloid secretion channel, 第2作者, 2014
Crystal structure of lipid phosphatase Escherichia coli phosphatidylglycerophosphate phosphatase B., 第3作者, 2014
Atomic resolution structure of the E. coli YajR transporter YAM domain, 第2作者, 2014
Structure of the YajR transporter suggests a transport mechanism based on the conserved motif A, 第2作者, 2013
Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum, 第4作者, 2012
Crystal structure of 1,3Gal43A, an exo-beta-1,3-galactanase from Clostridium thermocellum, 第4作者, 2012

膜蛋白结构功能生物物理冷冻电镜蛋白质复合物离子通道运输机制突触传递分子生物学

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